期刊
MOLECULAR CELL
卷 45, 期 4, 页码 433-434出版社
CELL PRESS
DOI: 10.1016/j.molcel.2012.02.003
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资金
- NHGRI NIH HHS [R01 HG004659, R01 HG004659-05] Funding Source: Medline
- NIGMS NIH HHS [R01 GM049369-19, R01 GM052872, R01 GM052872-14, R01 GM049369] Funding Source: Medline
Transcription is coupled with pre-mRNA splicing in metazoans. In the current issue of Molecular Cell, Huang et al. (2012) show that Med23 interacts with the RNA binding protein hnRNP L to regulate alternative splicing, thus expanding Mediator's function beyond transcriptional control.
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