期刊
MOLECULAR CELL
卷 43, 期 5, 页码 697-698出版社
CELL PRESS
DOI: 10.1016/j.molcel.2011.08.012
关键词
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资金
- NIDDK NIH HHS [R01 DK078024] Funding Source: Medline
In this issue of Molecular Cell, Wu et al. (2011) reveal an essential role for a chromatin modifier, histone deacetylase 3 (HDAC3), in hypoxia-induced epithelial-mesenchymal transition (EMT); HIF-activated HDAC3 integrates with WDR5 to impose chromatin modifications that culminate in EMT.
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