Antiproliferative effects of pomegranate extract in MCF-7 breast cancer cells are associated with reduced DNA repair gene expression and induction of double strand breaks

DNA Repair by Homologous Recombination, But Not by Nonhomologous End Joining, Is Elevated in Breast Cancer Cells

(2015) Zhiyong Mao et al.   NEOPLASIA

MicroRNAs in cancer management and their modulation by dietary agents

(2012) Tommy Karius et al.   BIOCHEMICAL PHARMACOLOGY

Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells

(2011) Lei Wang et al.   Integrative Biology

Rad51 and BRCA2 - New Molecular Targets for Sensitizing Glioma Cells to Alkylating Anticancer Drugs

(2011) Steve Quiros et al.   PLoS One

Pomegranate Ellagitannin-Derived Compounds Exhibit Antiproliferative and Antiaromatase Activity in Breast Cancer Cells In vitro

(2010) L. S. Adams et al.   Cancer Prevention Research

Homologous recombination in cancer development, treatment and development of drug resistance

(2010) T. Helleday   CARCINOGENESIS

Collaboration and competition between DNA double-strand break repair pathways

(2010) Elizabeth M. Kass et al.   FEBS LETTERS

Colon Cancer Chemopreventive Activities of Pomegranate Ellagitannins and Urolithins

(2010) Sashi G. Kasimsetty et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Suppression of human prostate cancer PC-3 cell growth by N-acetylcysteine involves over-expression of Cyr61

(2010) Yoon-Jin Lee et al.   TOXICOLOGY IN VITRO

Intestinal Mucosal Inflammation Leads to Systemic Genotoxicity in Mice

(2009) A. M. Westbrook et al.   CANCER RESEARCH

Pomegranate Fruit Extract Impairs Invasion and Motility in Human Breast Cancer

(2009) Gazala N. Khan et al.   INTEGRATIVE CANCER THERAPIES

MRE11-RAD50-NBS1 Complex Dictates DNA Repair Independent of H2AX

(2009) Jingsong Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-κB in human KU812 cells

(2009) Zafar Rasheed et al.   Journal of Inflammation-London

Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity

(2009) A. Choudhury et al.   MOLECULAR CANCER THERAPEUTICS

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

(2009) Ashish Lal et al.   MOLECULAR CELL

Cancer Chemoprevention by Pomegranate: Laboratory and Clinical Evidence

(2009) Vaqar Mustafa Adhami et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Safety assessment of pomegranate fruit extract: Acute and subchronic toxicity studies

(2008) Chintan Patel et al.   FOOD AND CHEMICAL TOXICOLOGY

Accurate Assessment of the Bioactivities of Redox-Active Polyphenolics in Cell Culture

(2008) Kimberly N. Wisman et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Comparison of Antioxidant Potency of Commonly Consumed Polyphenol-Rich Beverages in the United States

(2008) Navindra P. Seeram et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pomegranate Juice and Extracts Provide Similar Levels of Plasma and Urinary Ellagitannin Metabolites in Human Subjects

(2008) Navindra P. Seeram et al.   JOURNAL OF MEDICINAL FOOD

Rad50 Is Dispensable for the Maintenance and Viability of Postmitotic Tissues

(2008) C. A. Adelman et al.   MOLECULAR AND CELLULAR BIOLOGY