A novel DNA intercalator, 8-methoxy pyrimido[4′,5′:4,5]thieno (2,3-b)quinoline-4(3H)-one induces apoptosis in cancer cells, inhibits the tumor progression and enhances lifespan in mice with tumor

Efficiency of nonhomologous DNA end joining varies among somatic tissues, despite similarity in mechanism

(2010) Sheetal Sharma et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Intercalative pyrimido[4′,5′:4,5]thieno(2,3-b)quinolines induce apoptosis in leukemic cells: a comparative study of methoxy and morpholino substitution

(2010) M. S. Shahabuddin et al.   INVESTIGATIONAL NEW DRUGS

A natural compound, methyl angolensate, induces mitochondrial pathway of apoptosis in Daudi cells

(2010) Kishore K. Chiruvella et al.   INVESTIGATIONAL NEW DRUGS

A novel structural derivative of natural alkaloid ellipticine, MDPSQ, induces necrosis in leukemic cells

(2010) M. S. Shahabuddin et al.   INVESTIGATIONAL NEW DRUGS

Anti-apoptotic Protein BCL2 Down-regulates DNA End Joining in Cancer Cells

(2010) Tadi Satish Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiangiogenic and antiproliferative effects of substituted-1,3,4-oxadiazole derivatives is mediated by down regulation of VEGF and inhibition of translocation of HIF-1α in Ehrlich ascites tumor cells

(2009) Akhilesh Kumar et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A novel DNA intercalator, butylamino-pyrimido[4′,5′:4,5]selenolo(2,3-b)quinoline, induces cell cycle arrest and apoptosis in leukemic cells

(2009) M. S. Shahabuddin et al.   INVESTIGATIONAL NEW DRUGS

Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells

(2008) C.V. Kavitha et al.   BIOCHEMICAL PHARMACOLOGY

Bcl-2-family proteins and hematologic malignancies: history and future prospects

(2008) J. C. Reed   BLOOD

Antioxidant potential by arabinoxylan rice bran, MGN-3/biobran, represents a mechanism for its oncostatic effect against murine solid Ehrlich carcinoma

(2008) Eman Noaman et al.   CANCER LETTERS

Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells

(2008) Kishore K. Chiruvella et al.   FEBS LETTERS

Intercalating, cytotoxic, antitumour activity of 8-chloro and 4-morpholinopyrimido [4′,5′:4,5]thieno(2,3-b)quinolines

(2008) M.S. Shahabuddin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY