期刊
SCIENCE CHINA-LIFE SCIENCES
卷 58, 期 2, 页码 170-177出版社
SCIENCE PRESS
DOI: 10.1007/s11427-015-4806-7
关键词
fish directional breeding; polyploidy breeding; nuclear transfer; transgenic fish; genome editing
类别
资金
- National Basic Research Program of China [2010CB126306, 2012CB944504]
- National Science Fund for Excellent Young Scholars of the National Natural Science Foundation of China [31222052]
- Chinese Academy of Sciences [KSCX2-EW-N-004-4]
- State Key Laboratory of Freshwater Ecology and Biotechnology [2011FBZ23]
Aquaculture is one of the fastest developing agricultural industries worldwide. One of the most important factors for sustainable aquaculture is the development of high performing culture strains. Genome manipulation offers a powerful method to achieve rapid and directional breeding in fish. We review the history of fish breeding methods based on classical genome manipulation, including polyploidy breeding and nuclear transfer. Then, we discuss the advances and applications of fish directional breeding based on transgenic technology and recently developed genome editing technologies. These methods offer increased efficiency, precision and predictability in genetic improvement over traditional methods.
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