The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors

Insights into the oncogenic effects of /PIK3CA/ mutations from the structure of p110α/p85α

(2011) Chuan-Hsiang Huang et al.   CELL CYCLE

Statistical method on nonrandom clustering with application to somatic mutations in cancer

(2010) Jingjing Ye et al.   BMC BIOINFORMATICS

Inferring the functional effects of mutation through clusters of mutations in homologous proteins

(2010) Peng Yue et al.   HUMAN MUTATION

Structural and Functional Restraints on the Occurrence of Single Amino Acid Variations in Human Proteins

(2010) Sungsam Gong et al.   PLoS One

Accumulation of driver and passenger mutations during tumor progression

(2010) I. Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-Specific High-Throughput Annotation of Somatic Mutations: Computational Prediction of Driver Missense Mutations

(2009) H. Carter et al.   CANCER RESEARCH

The SAAPdb web resource: A large-scale structural analysis of mutant proteins

(2009) Jacob M. Hurst et al.   HUMAN MUTATION

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Prediction of Cancer Driver Mutations in Protein Kinases

(2008) A. Torkamani et al.   CANCER RESEARCH

Functional classification analysis of somatically mutated genes in human breast and colorectal cancers

(2008) Thomas W. Chittenden et al.   GENOMICS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE