期刊
MOLECULAR BREEDING
卷 30, 期 2, 页码 831-843出版社
SPRINGER
DOI: 10.1007/s11032-011-9667-6
关键词
Barley; Association genetics studies; Linkage disequilibrium; Population structure; SNPs; Marker-assisted selection
资金
- German Research Foundation (DFG), part of the Collaborative Research Centre at University of Giessen [(SFB) 299]
- Federal Ministry of Education and Research (BMBF) [FKZ 03115066 A-E]
A genome-wide association mapping approach for grain yield and traits of high agronomic relevance was carried out on basis of a set of 61 six-rowed and 48 two-rowed German winter barley (Hordeum vulgare L.) cultivars representing breeding progress in the period 1959-2003. Extensive phenotyping was conducted in field trials carried out at 12 locations in 3 years. Heritability was estimated at between 0.45 for grain yield and 0.94 for grains per spike. By using the Illumina Golden Gate Bead Array technology, 833 single nucleotide polymorphisms with an allele frequency higher than 5% were obtained. Linkage disequilibrium on the whole genome extends to 7.35 cM. Based on a mixed linear model approach taking into account the population structure estimated on the basis of 72 simple sequence repeat markers covering the whole barley genome, 91 significant marker-trait associations were detected, corresponding to 48 different genomic regions.
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