Article
Energy & Fuels
Zakiullah Zaidi, Laxmi Gayatri Sorokhaibam
Summary: A novel chemical-biological approach using molybdenum and Rhodococcus erythropolis for liquid fuel desulfurization was investigated. The results show that Rh-Mo@FAT can significantly reduce the concentration of organosulfur compounds in fuel oil.
Article
Energy & Fuels
Hussein N. Nassar, Hager R. Ali, Nour Sh El-Gendy
Summary: A novel method using superparamagnetic iron oxide nanoparticles prepared from mandarin peels was applied to enhance the desulfurizing activity of Rhodococcus erythropolis HN2. The biofunctionalized nanoparticles proved to be non-toxic for HN2 and improved its desulfurization efficiency at high oil feed concentrations, with easy separability.
Article
Microbiology
Zachary J. Butz, Alexander Hendricks, Kanda Borgognoni, Christopher J. Ackerson
Summary: A Rhodococcus erythropolis bacterium was identified to tolerate normally lethal concentrations of various metal ions, with a mycothione reductase (Mtr) showing remarkable selectivity for TeO32- reduction. The selectivity for TeO32- is attributed to aromatic residues near the active site of the enzyme, resulting in a Te-0 enzymatic product resembling Te nanowires.
FEMS MICROBIOLOGY ECOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Valentine E. Anyanwu, Stephen J. Hall, Gill Stephens, Anca Pordea
Summary: This study demonstrates the potential of putrescine oxidase from Rhodococcus erythropolis for the bioproduction of N-heterocycles from cadaverine. The enzyme showed good activity under optimal temperature and pH conditions, with complete biotransformation of cadaverine observed in whole cells. A direct assay of enzyme activity for cadaverine oxidation was successfully implemented, confirming the efficiency of the enzyme for this biotechnological application.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2021)
Article
Microbiology
Dawid Hernik, Francesco Gatti, Elisabetta Brenna, Ewa Szczepanska, Teresa Olejniczak, Filip Boratynski
Summary: This study developed an efficient and highly stereoselective method for the synthesis of individual enantiomeric forms of whisky lactones. Among various bacteria, R. erythropolis effectively oxidized diols to corresponding enantiomerically pure whisky lactones. The newly developed method provides an improved approach for the synthesis of chiral whisky lactones.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Plant Sciences
Dinara Oshanova, Assylay Kurmanbayeva, Aizat Bekturova, Aigerim Soltabayeva, Zhadyrassyn Nurbekova, Dominic Standing, Arvind Kumar Dubey, Moshe Sagi
Summary: The study highlights the important role of sulfite oxidase (SO) in carbon and sulfur metabolism in plants, not only protecting against elevated sulfite toxicity but also maintaining optimal levels. Results showed that impairment of SO led to an overflow of organic S accumulation and oxidative stress, contributing to lower biomass accumulation rates in Arabidopsis plants.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Engineering, Environmental
Tieyue Qi, Shuo Zhang, Jingzhao Zhang, Tong Li, Lei Xing, Zhimo Fang, Shanlong An, Zhongfei Xu, Huining Xiao, Lidong Wang
Summary: This study proposes a waste control method to treat wastewater containing highly toxic Cr(VI) and sulfite. Through the redox reaction of Cr(VI)-sulfite, highly toxic Cr(VI) is converted into non-toxic substances and enriched on a novel biochar-induced cobalt-based silica composite. This method effectively reduces the harm to aquatic life and human health.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Microbiology
Miao Yu, Zhiwen Zhu, Bing Chen, Yiqi Cao, Baiyu Zhang
Summary: This study evaluated a biosurfactant produced by Rhodococcus erythropolis M25 as an effective and eco-friendly herding agent. The impact of environmental and operational factors on its performance was investigated and the results showed that higher temperature and a higher dose of herder could increase the herding effectiveness.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Seokho Hong, Jinshil Kim, Eunshin Cho, Soohui Na, Yeon-Ji Yoo, You-Hee Cho, Sangryeol Ryu, Nam-Chul Ha
Summary: Cronobacter sakazakii is an emerging pathogenic bacterium that causes various diseases in infants. The study identified YeiE as a global virulence regulator and investigated its role in the response to sulfite and its toxicity during bacterial growth. The research revealed the structural changes of YeiE in the presence of sulfite and its functional roles in H2S production and survival capability from neutrophils.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Plant Sciences
Aizat Bekturova, Dinara Oshanova, Poonam Tiwari, Zhadyrassyn Nurbekova, Assylay Kurmanbayeva, Aigerim Soltabayeva, Dmitry Yarmolinsky, Sudhakar Srivastava, Veronika Tureckova, Miroslav Strnad, Moshe Sagi
Summary: The study revealed the important roles of adenosine-5'-phosphosulphate reductase (APR) and sulfite oxidase (SO) in sulfite homeostasis, affecting water consumption and stomatal aperture in plants.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Microbiology
Cristina Parada, Isabel Cecilia Neri-Badillo, Antonio J. Vallecillo, Erika Segura, Mayra Silva-Miranda, Silvia Laura Guzman-Gutierrez, Paola A. Ortega, Enrique Wenceslao Coronado-Aceves, Laura Cancino-Villeda, Alfredo Torres-Larios, Michel de Jesus Aceves Sanchez, Mario Alberto Flores Valdez, Clara Espitia
Summary: The study highlights the importance of protein methylation in modulating immune response and fatty acid transport in Mycobacterium tuberculosis. This provides new insights into the pathogenesis of tuberculosis and underscores the significance of heterologous expression systems in obtaining modified proteins.
Article
Engineering, Environmental
Tieyue Qi, Shuo Zhang, Tong Li, Lei Xing, Shanlong An, Qiangwei Li, Lidong Wang
Summary: This study fabricates nitrogen-doped porous carbon coembedded with lanthanum and cobalt (La-Co@NPC) as a dual-functional catalyst for sulfite oxidation and arsenic removal in the desulfurization process. The La-Co@NPC/S(IV) catalytic system generates strongly oxidizing free radicals for sulfite oxidation and oxidizes As(III) into As(V). The results show high efficiency in ammonium sulfite oxidation and arsenic removal, making it significant for the high-value recovery of sulfur resources in coal-fired desulfurization.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Food Science & Technology
Sujin Park, YoonA Kim, Jaewang Lee, Hyunsoo Seo, Sang-Jip Nam, Dong-Gyu Jo, Dong-Hoon Hyun
Summary: This study investigates the neuroprotective effects of 4-hydroxycinnamic acid (HCA) by analyzing cell survival, abnormal protein levels, and mitochondrial functions. The results show that HCA protects neuronal cells by increasing the expression of plasma membrane redox enzymes and improving the NAD+/NADH ratio. HCA also enhances mitochondrial activities, ATP production, and promotes mitochondrial fusion while decreasing mitochondrial fission. These findings suggest that HCA could be a promising therapeutic approach for neurodegenerative diseases.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Review
Engineering, Environmental
Shuai Liu, Zewei Liu, Hengxi Zhu, Zixuan Wang, Junjiang Guo, Xiaoyue Zhang, Hongxin Yu, Xiangdong Yue, Ping Ning, Bin Li
Summary: This paper is a review of the role of red mud in flue gas desulfurization and denitrification. It compares new technologies with traditional ones and summarizes the characteristics, advantages, and disadvantages of new technologies, providing a foundation for their large-scale application. The review also gives suggestions for future research on red mud utilization, desulfurization technology, and denitration technology.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Daniel T. Murray, Kevin L. Weiss, Christopher B. Stanley, Gergely Nagy, M. Elizabeth Stroupe
Summary: The study presents the solution structures of Sulfite reductase (SiR) heterodimers, showing how the subunits bind and how both subunit binding and oxidation state impact SiRF's conformation. SiRHP binding induces a change in SiRFP's position, while reduction of SiRFP leads to a more open structure for electron transfer between the subunits. These results provide insights into the mechanisms of electron transfer within SiR.
JOURNAL OF STRUCTURAL BIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Hock Chuan Yeo, Seo-Young Park, Tessa Tan, Say K. Ng, Meiyappan Lakshmanan, Dong-Yup Lee
Summary: This study combined partial least square regression (PLS-R) with flux balance analysis to systematically investigate the metabolic bottlenecks of CHO cells under different media conditions. By analyzing metabolite exchanges and metabolic states, the study identified the factors hindering cell growth and productivity, providing nutrient targets for media reformulation.
BIOTECHNOLOGY AND BIOENGINEERING
(2022)
Article
Chemistry, Physical
Xiaodong Hong, Sushant S. Garud, Vaishali B. Thaore, Iftekhar A. Karimi, Shamsuzzaman Farooq, Xiaonan Wang, Adam K. Usadi, Bryan R. Chapman, Robert A. Johnson
Summary: This paper introduces a tool called HEART for assessing and planning the hydrogen economy in the ASEAN region. The tool enables techno-enviro-economic analysis, demand projection, and supply chain optimization of hydrogen. The case study demonstrates the tool's capability to provide useful results and optimize the hydrogen industry.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Energy & Fuels
Hani Ababneh, Ahmed AlNouss, Iftekhar A. Karimi, Shaheen A. Al-Muhtaseb
Summary: This article presents a new solid-vapor separation unit for removing acid gases from sour natural gas. The unit offers advantages in terms of energy and capital costs, and outperforms conventional methods used by the industry.
Article
Engineering, Chemical
Anikesh Kumar, Lakshminarayanan Samavedham, Iftekhar A. Karimi, Rajagopalan Srinivasan
Summary: Safety and economic constraints in industrial processes are not well handled by conventional control systems, leading to the addition of ad hoc elements and more sophisticated control strategies. Recent developments suggest model predictive control (MPC) as a more natural approach. This work evaluates the efficacy of ad hoc additions to handle constraints and applies it to a continuously stirred tank reactor model and a heat exchanger system, demonstrating the limitations of the approach and the improvement achieved with MPC.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2022)
Article
Energy & Fuels
Shivom Sharma, Iftekhar A. Karimi, Shamsuzzaman Farooq, Lakshminarayanan Samavedham, Rajagopalan Srinivasan
Summary: Mathematical models were developed for spring-loaded and lever-type regulators to diagnose faults, track prognoses, and estimate remaining useful life. The proposed methodologies were validated using real data and packaged into a user-friendly dashboard for industrial use.
Article
Biotechnology & Applied Microbiology
Jong Kwang Hong, Dong-Hyuk Choi, Seo-Young Park, Yaron R. Silberberg, Fumi Shozui, Eiji Nakamura, Takashi Kayahara, Dong-Yup Lee
Summary: A systematic media design framework combining statistical approaches and in silico analysis was proposed to improve cell culture performance by identifying target media components.
METABOLIC ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Chi Hung Vo, Javier Perez-Ramirez, Shamsuzzaman Farooq, Iftekhar A. Karimi
Summary: Higher alcohols have the potential to be widely used in large-scale CO2 utilization, serving as chemical energy carriers and fuel additives. In this study, prospective techno-economic and environmental evaluations were conducted to examine the synthesis of 1-propanol, 1-butanol, 1-pentanol, and 1-hexanol from captured CO2 and green H2. The results showed that 1-pentanol and 1-hexanol plants are economically viable, while the costs of manufacturing the other two alcohols exceed their revenues. Sensitivity analysis suggested that the cost of H2 needs to be reduced for the processes to break even. A hybrid process combining a recently studied synthesis route and the novel route based solely on CO2 was found to reduce carbon footprint and be profitable.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Thermodynamics
Zuming Liu, Arijit Chakraborty, Tianbiao He, Iftekhar A. Karimi
Summary: The chemical industry relies heavily on fossil fuels, resulting in significant carbon emissions. Implementing combined heat and power (CHP) systems can effectively reduce both energy consumption and carbon emissions. This study presents a bi-objective optimization framework for CHP systems in chemical plants, considering steam turbine network design and renewable integration. The results demonstrate the trade-off between total annual cost and carbon emissions, showing the potential for emissions reduction through CHP systems.
APPLIED THERMAL ENGINEERING
(2023)
Article
Chemistry, Physical
Xiaodong Hong, Vaishali B. Thaore, Sushant S. Garud, Iftekhar A. Karimi, Shamsuzzaman Farooq, Xiaonan Wang, Adam K. Usadi, Bryan R. Chapman
Summary: The interest in low emissions hydrogen as a means to achieve deep decarbonization goals has been increasing. This paper explores the local production of blue hydrogen from natural gas with CO2 capture and sequestration in order to support Singapore's efforts in reducing carbon emissions. A model is used to analyze the costs and emissions associated with the entire supply chain, and it is found that decarbonizing Singapore through the local production of blue hydrogen will involve a relatively high carbon avoidance cost.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Biotechnology & Applied Microbiology
Seo-Young Park, Sun-Jong Kim, Cheol-Hwan Park, Jiyong Kim, Dong-Yup Lee
Summary: Recent advances in process analytical technology and artificial intelligence have made it possible to generate large culture data sets from biomanufacturing processes. Exploiting these data sets is crucial for improving the reliability and efficiency of RTP-producing culture processes and reducing potential faults.
BIOTECHNOLOGY AND BIOENGINEERING
(2023)
Article
Biochemical Research Methods
Seo-Young Park, Dong-Hyuk Choi, Jinsung Song, Uiseon Park, Hyeran Cho, Bee Hak Hong, Yaron R. Silberberg, Dong-Yup Lee
Summary: Designing and selecting cell culture media and feed is crucial for maximizing culture performance in biopharmaceutical processes. This study focused on investigating the effect of growth media and feed on Chinese hamster ovary (CHO) cell culture and identified target components for improving cell longevity, specific growth rate, and productivity. The findings suggest that adjusting the amounts of targeted amino acids in the feed can significantly enhance cell culture outcomes.
BIOTECHNOLOGY JOURNAL
(2023)
Article
Thermodynamics
Wenliang Meng, Dongliang Wang, Huairong Zhou, Yong Yang, Hongwei Li, Zuwei Liao, Siyu Yang, Xiaodong Hong, Guixian Li
Summary: A high proportion of renewable energy integration is a characteristic of future electric power grid, and power-to-NH3 technologies will be crucial for inter-quarter long-term energy storage. In addition, CO2 capture in coal-based power plants is essential for peak regulation. This study developed a novel urea synthesis process based on renewable energy, which resulted in significantly lower CO2 emissions compared to traditional coal and natural gas-based processes. While the production cost of the new process is higher, it becomes more economical when considering carbon tax values.
Article
Engineering, Chemical
Dnyanesh Deshpande, Mohd Shahrukh, Rajagopalan Srinivasan, Iftekhar A. Karimi
Summary: This study investigates the annual delivery program (ADP) problem for natural gas suppliers, incorporating customer inventory and berth management, customer demand satisfaction, and the delivery of multiple LNG grades. A mathematical programming model is proposed to maximize the supplier's profit.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Aruna Coimbatore Meenakshi Sundaram, Iftekhar A. Karimi
Summary: IMO's 2020 regulation aims to replace heavy fuel oil with cleaner and sustainable bunkering fuels in the maritime industry. Liquefied natural gas (LNG) is a promising solution for meeting emission standards, but requires new infrastructures and protocols for bunkering. This study evaluates LNG bunkering procedure using dynamic simulation, estimating bunkering time, costs, and emissions for different scenarios.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Yoon-Mi Choi, Dong-Hyuk Choi, Yi Qing Lee, Lokanand Koduru, Nathan E. Lewis, Meiyappan Lakshmanan, Dong-Yup Lee
Summary: The biomass equation in genome-scale metabolic models is used as the de facto objective function in flux balance analysis. However, the macromolecular composition of cells can change across different environmental conditions, raising concerns about the use of the same biomass equation in multiple conditions. Through qualitative and quantitative investigations, it was found that while macromolecular building blocks vary notably, the fundamental biomass monomer units are not appreciably different. Based on these findings, ensemble representations of the biomass equation were proposed to account for the natural variation of cellular constituents, leading to more accurate flux predictions.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
(2023)