An omics perspective of protein disorder

Intrinsically disordered chaperones in plants and animalsThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.

(2010) Peter Tompa et al.   Biochemistry and Cell Biology

Molecular simulations of protein disorderThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.

(2010) Sarah Rauscher et al.   Biochemistry and Cell Biology

Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be

(2010) Christian Schaefer et al.   BIOINFORMATICS

Charge-Rich Regions Modulate the Anti-Aggregation Activity of Hsp90

(2010) Natalie Wayne et al.   JOURNAL OF MOLECULAR BIOLOGY

Evolution of Characterized Phosphorylation Sites in Budding Yeast

(2010) A. N. Nguyen Ba et al.   MOLECULAR BIOLOGY AND EVOLUTION

Consistent refinement of submitted models at CASP using a knowledge-based potential

(2010) Gaurav Chopra et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs

(2010) J. Mok et al.   Science Signaling

Protein disorder in the human diseasome: unfoldomics of human genetic diseases

(2009) Uros Midic et al.   BMC GENOMICS

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

(2009) Vladimir N Uversky et al.   BMC GENOMICS

Intrinsic Protein Disorder and Interaction Promiscuity Are Widely Associated with Dosage Sensitivity

(2009) Tanya Vavouri et al.   CELL

Disorder, Promiscuity, and Toxic Partnerships

(2009) Edward M. Marcotte et al.   CELL

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response

(2009) Peter Tsvetkov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Investigating the disorder-order transition of calmodulin binding domain upon binding calmodulin using molecular dynamics simulation

(2009) Yong Zhang et al.   JOURNAL OF MOLECULAR RECOGNITION

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90

(2009) Martin Hessling et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ELM: the status of the 2010 eukaryotic linear motif resource

(2009) Cathryn M. Gould et al.   NUCLEIC ACIDS RESEARCH

Improved Disorder Prediction by Combination of Orthogonal Approaches

(2009) Avner Schlessinger et al.   PLoS One

Modularity of intrinsic disorder in the human proteome

(2009) Melissa M. Pentony et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Assessment of disorder predictions in CASP8

(2009) Orly Noivirt-Brik et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases

(2009) C. S. H. Tan et al.   Science Signaling

Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species

(2009) Pedro Beltrao et al.   PLOS BIOLOGY

Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins

(2009) Raffi Tonikian et al.   PLOS BIOLOGY

Integrated Assessment of Genomic Correlates of Protein Evolutionary Rate

(2009) Yu Xia et al.   PLoS Computational Biology

Intrinsic Disorder in Protein Interactions: Insights From a Comprehensive Structural Analysis

(2009) Jessica H. Fong et al.   PLoS Computational Biology

Prediction of disordered regions in proteins based on the meta approach

(2008) T. Ishida et al.   BIOINFORMATICS

The unfoldomics decade: an update on intrinsically disordered proteins

(2008) A Keith Dunker et al.   BMC GENOMICS

Understanding eukaryotic linear motifs and their role in cell signaling and regulation

(2008) Francesca Diella   Frontiers in Bioscience-Landmark

Hydrophilic Residues526KNDAAD531in the Flexible C-terminal Region of the Chaperonin GroEL Are Critical for Substrate Protein Folding within the Central Cavity

(2008) Kodai Machida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoproteomic Analysis of the Mouse Brain Cytosol Reveals a Predominance of Protein Phosphorylation in Regions of Intrinsic Sequence Disorder

(2008) Mark O. Collins et al.   MOLECULAR & CELLULAR PROTEOMICS

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

(2008) H. Yu et al.   SCIENCE

An in Vivo Map of the Yeast Protein Interactome

(2008) K. Tarassov et al.   SCIENCE

Tight Regulation of Unstructured Proteins: From Transcript Synthesis to Protein Degradation

(2008) J. Gsponer et al.   SCIENCE

Linear Motif Atlas for Phosphorylation-Dependent Signaling

(2008) M. L. Miller et al.   Science Signaling

Structural disorder serves as a weak signal for intracellular protein degradation

(2007) P. Tompa et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

(2007) Peter Tompa et al.   TRENDS IN BIOCHEMICAL SCIENCES