Mutation of SIMPLE in Charcot–Marie–Tooth 1C alters production of exosomes

LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: Implications for Charcot-Marie-Tooth disease

(2012) Christian Somandin et al.   GLIA

p38 MAPK Activation Promotes Denervated Schwann Cell Phenotype and Functions as a Negative Regulator of Schwann Cell Differentiation and Myelination

(2012) D. P. Yang et al.   JOURNAL OF NEUROSCIENCE

Exosomal cell-to-cell transmission of alpha synuclein oligomers

(2012) Karin M Danzer et al.   Molecular Neurodegeneration

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Intercellular communication: diverse structures for exchange of genetic information

(2012) Maria Mittelbrunn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intercellular (Mis)communication in Neurodegenerative Disease

(2012) Gwenn A. Garden et al.   NEURON

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

(2012) J. F. Nabhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways

(2011) S. M. Lee et al.   JOURNAL OF CELL SCIENCE

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

(2011) Rebecca A. Dragovic et al.   Nanomedicine-Nanotechnology Biology and Medicine

Shaping development with ESCRTs

(2011) Tor Erik Rusten et al.   NATURE CELL BIOLOGY

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission

(2011) Lydia Alvarez-Erviti et al.   NEUROBIOLOGY OF DISEASE

SIMPLE/LITAF Expression Induces the Translocation of the Ubiquitin Ligase Itch towards the Lysosomal Compartments

(2011) Heather E. Eaton et al.   PLoS One

The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein

(2011) Takafumi Hasegawa et al.   PLoS One

Whole-body deletion of LPS-induced TNF-  factor (LITAF) markedly improves experimental endotoxic shock and inflammatory arthritis

(2011) J. C. Merrill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Membrane Budding

(2010) James H. Hurley et al.   CELL

Rab7: Role of its protein interaction cascades in endo-lysosomal traffic

(2010) Tuanlao Wang et al.   CELLULAR SIGNALLING

Beneficial Dysregulation of the Time Course of Inflammatory Mediators in Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Factor-Deficient Mice

(2010) S. Srinivasan et al.   Clinical and Vaccine Immunology

The ESCRT complexes

(2010) James H. Hurley   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cell-Produced  -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

(2010) E. Emmanouilidou et al.   JOURNAL OF NEUROSCIENCE

Multiple Interactions between the ESCRT Machinery and Arrestin-Related Proteins: Implications for PPXY-Dependent Budding

(2010) S. Rauch et al.   JOURNAL OF VIROLOGY

Membrane budding and scission by the ESCRT machinery: it's all in the neck

(2010) James H. Hurley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signals to promote myelin formation and repair

(2010) Carla Taveggia et al.   Nature Reviews Neurology

Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages

(2010) Pramod K. Giri et al.   PROTEOMICS

Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence

(2009) Bradley M. Coleman et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ESCRTs and human disease

(2009) Suraj Saksena et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

Charcot–Marie–Tooth disease

(2009) Kinga Szigeti et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Missense mutations in the SH3TC2 protein causing Charcot-Marie-Tooth disease type 4C affect its localization in the plasma membrane and endocytic pathway

(2009) Vincenzo Lupo et al.   HUMAN MOLECULAR GENETICS

Hereditary motor and sensory neuropathy caused by a novel mutation in LITAF

(2009) Wanda Maria Gerding et al.   NEUROMUSCULAR DISORDERS

ExoCarta: A compendium of exosomal proteins and RNA

(2009) Suresh Mathivanan et al.   PROTEOMICS

ESCRT proteins in physiology and disease

(2008) Susanne Stuffers et al.   EXPERIMENTAL CELL RESEARCH

Molecular assemblies and membrane domains in multivesicular endosome dynamics

(2008) Thomas Falguières et al.   EXPERIMENTAL CELL RESEARCH

Negative regulation of myelination: Relevance for development, injury, and demyelinating disease

(2008) Kristján R. Jessen et al.   GLIA

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE

Exosomes Derived from M. Bovis BCG Infected Macrophages Activate Antigen-Specific CD4+ and CD8+ T Cells In Vitro and In Vivo

(2008) Pramod K. Giri et al.   PLoS One

Proteomic profiling of exosomes: Current perspectives

(2008) Richard J. Simpson et al.   PROTEOMICS

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

Systems Biology of Growth Factor-Induced Receptor Endocytosis

(2008) Yaara Zwang et al.   TRAFFIC