Systematic humanization of yeast genes reveals conserved functions and genetic modularity

Galactose metabolic genes in yeast respond to a ratio of galactose and glucose

(2015) Renan Escalante-Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Functional and evolutionary implications of gene orthology

(2013) Toni Gabaldón et al.   NATURE REVIEWS GENETICS

Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions

(2012) Adam Frost et al.   CELL

Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

(2012) Colm J. Ryan et al.   MOLECULAR CELL

The Ortholog Conjecture Is Untestable by the Current Gene Ontology but Is Supported by RNA Sequencing Data

(2012) Xiaoshu Chen et al.   PLoS Computational Biology

Significant liver disease in a patient with Y116H mutation in the MVK gene

(2011) Melissa Leyva-Vega et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Prioritizing candidate disease genes by network-based boosting of genome-wide association data

(2011) I. Lee et al.   GENOME RESEARCH

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

(2011) Zhijian Li et al.   NATURE BIOTECHNOLOGY

Testing the Ortholog Conjecture with Comparative Functional Genomic Data from Mammals

(2011) Nathan L. Nehrt et al.   PLoS Computational Biology

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action

(2010) Laura Kapitzky et al.   Molecular Systems Biology

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Characterization of the proteome, diseases and evolution of the human postsynaptic density

(2010) Àlex Bayés et al.   NATURE NEUROSCIENCE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

The Use of Orthologous Sequences to Predict the Impact of Amino Acid Substitutions on Protein Function

(2010) Nicholas J. Marini et al.   PLoS Genetics

Intrinsic Protein Disorder and Interaction Promiscuity Are Widely Associated with Dosage Sensitivity

(2009) Tanya Vavouri et al.   CELL

The completion of the Mammalian Gene Collection (MGC)

(2009) et al.   GENOME RESEARCH

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE