期刊
MOLECULAR BIOLOGY
卷 46, 期 2, 页码 175-182出版社
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S0026893312020136
关键词
CRISPR systems; Cas proteins; small RNAs; adaptive immunity
资金
- Presidium of the Russian Academy of Sciences
- Russian Foundation for Basic Research [1-04-01373]
- philanthropic research-supporting foundation
CRISPR (clustered regularly interspaced short palindromic repeats) systems were found in the genomes of many eubacteria and the vast majority of archaea. Their unique feature is that CRISPR-mediated immunity is adaptive and can be programmed to protect cells against mobile genetic elements. The review describes the general principles of CRISPR-mediated immunity and characterizes the CRISPR systems of various microorganisms.
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