Macrophage Fusion Is Controlled by the Cytoplasmic Protein Tyrosine Phosphatase PTP-PEST/PTPN12

The Phosphatase PTP-PEST/PTPN12 Regulates Endothelial Cell Migration and Adhesion, but Not Permeability, and Controls Vascular Development and Embryonic Viability

(2012) Cleiton Martins Souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lack of TNF-α–Induced MMP-9 Production and Abnormal E-Cadherin Redistribution Associated with Compromised Fusion in MCP-1–Null Macrophages

(2011) Eleni A. Skokos et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase

(2011) Tingting Sun et al.   CELL

Inositol Polyphosphate 4-Phosphatase B as a Regulator of Bone Mass in Mice and Humans

(2011) Mathieu Ferron et al.   Cell Metabolism

Understanding the Impact of the P-loop Conformation on Kinase Selectivity

(2011) Cristiano R. W. Guimarães et al.   Journal of Chemical Information and Modeling

The Phosphatase PTP-PEST Promotes Secondary T Cell Responses by Dephosphorylating the Protein Tyrosine Kinase Pyk2

(2010) Dominique Davidson et al.   IMMUNITY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Phosphoproteomic characterization of PYK2 signaling pathways involved in osteogenesis

(2010) Peter C. Bonnette et al.   Journal of Proteomics

A Transgenic Mouse Model of Inducible Macrophage Depletion

(2009) Itamar Goren et al.   AMERICAN JOURNAL OF PATHOLOGY

Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes

(2009) J. Van den Bossche et al.   BLOOD

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation

(2009) Parag J. Bhavsar et al.   EXPERIMENTAL CELL RESEARCH

PEST family phosphatases in immunity, autoimmunity, and autoinflammatory disorders

(2009) André Veillette et al.   IMMUNOLOGICAL REVIEWS

B Cell Receptor-induced Phosphorylation of Pyk2 and Focal Adhesion Kinase Involves Integrins and the Rap GTPases and Is Required for B Cell Spreading

(2009) Kathy W. K. Tse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mediators of macrophage fusion

(2009) Laura Helming et al.   TRENDS IN CELL BIOLOGY

A tal(in) of cell spreading

(2008) Margaret Frame et al.   NATURE CELL BIOLOGY

Essential Role of DAP12 Signaling in Macrophage Programming into a Fusion-Competent State

(2008) L. Helming et al.   Science Signaling