Regulation of Focal Adhesion Kinase Activation, Breast Cancer Cell Motility, and Amoeboid Invasion by the RhoA Guanine Nucleotide Exchange Factor Net1

Neuroepithelial Transforming Gene 1 (Net1) Binds to Caspase Activation and Recruitment Domain (CARD)- and Membrane-associated Guanylate Kinase-like Domain-containing (CARMA) Proteins and Regulates Nuclear Factor κB Activation

(2012) Mariangela Vessichelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac1 Controls the Subcellular Localization of the Rho Guanine Nucleotide Exchange Factor Net1A To Regulate Focal Adhesion Formation and Cell Spreading

(2012) Heather S. Carr et al.   MOLECULAR AND CELLULAR BIOLOGY

Life at the Leading Edge

(2011) Anne J. Ridley   CELL

Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition

(2011) E Papadimitriou et al.   ONCOGENE

The Nuclear Guanine Nucleotide Exchange Factors Ect2 and Net1 Regulate RhoB-Mediated Cell Death after DNA Damage

(2011) Melissa C. Srougi et al.   PLoS One

Estrogen Regulation and Physiopathologic Significance of Alternative Promoters in Breast Cancer

(2010) Martin Dutertre et al.   CANCER RESEARCH

The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

(2010) Victoria Sanz-Moreno et al.   CURRENT OPINION IN CELL BIOLOGY

Over-expression of Neuroepithelial-transforming Protein 1 Confers Poor Prognosis of Patients with Gliomas

(2010) Y. Tu et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

(2010) Rebecca W. Scott et al.   JOURNAL OF CELL BIOLOGY

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

(2009) Shuh Narumiya et al.   CANCER AND METASTASIS REVIEWS

Coexpression of  6 4 Integrin and Guanine Nucleotide Exchange Factor Net1 Identifies Node-Positive Breast Cancer Patients at High Risk for Distant Metastasis

(2009) M. Z. Gilcrease et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Interaction of the RhoA Exchange Factor Net1 with Discs Large Homolog 1 Protects It from Proteasome-mediated Degradation and Potentiates Net1 Activity

(2009) Heather S. Carr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer

(2008) D Murray et al.   BRITISH JOURNAL OF CANCER

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

The actin cytoskeleton in cancer cell motility

(2008) Michael F. Olson et al.   CLINICAL & EXPERIMENTAL METASTASIS

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

(2008) Yangmi Lim et al.   JOURNAL OF CELL BIOLOGY

FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts

(2008) M. P. Iwanicki et al.   JOURNAL OF CELL SCIENCE

Expression and clinical significance of NET-1 and PCNA in hepatocellular carcinoma

(2008) Shi-Qiang Shen et al.   MEDICAL ONCOLOGY

Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

(2008) Ssang-Taek Lim et al.   MOLECULAR CELL

RhoA and microtubule dynamics control cell–basement membrane interaction in EMT during gastrulation

(2008) Yukiko Nakaya et al.   NATURE CELL BIOLOGY