Enhanced Leptin Sensitivity, Reduced Adiposity, and Improved Glucose Homeostasis in Mice Lacking Exchange Protein Directly Activated by Cyclic AMP Isoform 1

Medical Therapy for the Patient With Obesity

(2012) George A. Bray et al.   CIRCULATION

Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

(2012) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice

(2012) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

EPAC Null Mutation Impairs Learning and Social Interactions via Aberrant Regulation of miR-124 and Zif268 Translation

(2012) Ying Yang et al.   NEURON

Isoform-specific antagonists of exchange proteins directly activated by cAMP

(2012) T. Tsalkova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

8-Phenylthio-adenines stimulate the expression of steroid hydroxylases, Cav3.2 Ca2+ channels, and cortisol synthesis by a cAMP-independent mechanism

(2011) Judith A. Enyeart et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Induction of Leptin Resistance by Activation of cAMP-Epac Signaling

(2011) Makoto Fukuda et al.   Cell Metabolism

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

(2011) Mariel M Finucane et al.   LANCET

Increased Hypothalamic Signal Transducer and Activator of Transcription 3 Phosphorylation after Hindbrain Leptin Injection

(2010) Marieke Ruiter et al.   ENDOCRINOLOGY

PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

(2010) Ryoichi Banno et al.   JOURNAL OF CLINICAL INVESTIGATION

8-pCPT-conjugated cyclic AMP analogs exert thromboxane receptor antagonistic properties

(2010) Maria Grandoch et al.   THROMBOSIS AND HAEMOSTASIS

The effect of obesity on health outcomes

(2009) John B. Dixon   MOLECULAR AND CELLULAR ENDOCRINOLOGY

cAMP Analogs and Their Metabolites Enhance TREK-1 mRNA and K+ Current Expression in Adrenocortical Cells

(2009) J. A. Enyeart et al.   MOLECULAR PHARMACOLOGY

Validation of Computed Tomographic Estimates of Intra-abdominal and Subcutaneous Adipose Tissue in Rats and Mice

(2009) Jacquelien J.G. Hillebrand et al.   Obesity

Metabolites of an Epac-Selective cAMP Analog Induce Cortisol Synthesis by Adrenocortical Cells through a cAMP-Independent Pathway

(2009) Judith A. Enyeart et al.   PLoS One

The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs

(2009) C.-L. Zhang et al.   SCIENCE

Epac and PKA: a tale of two intracellular cAMP receptors

(2008) Xiaodong Cheng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Development of Diabesity in Mice with Neuronal Deletion of Shp2 Tyrosine Phosphatase

(2008) Maryla Krajewska et al.   AMERICAN JOURNAL OF PATHOLOGY

Cyclic AMP (cAMP)-Mediated Stimulation of Adipocyte Differentiation Requires the Synergistic Action of Epac- and cAMP-Dependent Protein Kinase-Dependent Processes

(2008) R. K. Petersen et al.   MOLECULAR AND CELLULAR BIOLOGY

PKA-dependent and independent cAMP signaling in 3T3-L1 fibroblasts differentiation

(2008) Claudia N. Martini et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cyclic nucleotide analogs as probes of signaling pathways

(2008) Heiko Poppe et al.   NATURE METHODS

Mechanisms of Leptin Action and Leptin Resistance

(2007) Martin G. Myers et al.   Annual Review of Physiology