A Transcriptional Regulatory Role of the THAP11-HCF-1 Complex in Colon Cancer Cell Function

THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death

(2010) Meenakshi P. Balakrishnan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

(2010) M. Dejosez et al.   GENES & DEVELOPMENT

The THAP-Zinc Finger Protein THAP1 Associates with Coactivator HCF-1 andO-GlcNAc Transferase

(2010) Raoul Mazars et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

(2010) H. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Deconstructing repression: evolving models of co-repressor action

(2010) Valentina Perissi et al.   NATURE REVIEWS GENETICS

Structural determinants of specific DNA-recognition by the THAP zinc finger

(2010) Sébastien Campagne et al.   NUCLEIC ACIDS RESEARCH

Praf2 Is a Novel Bcl-xL/Bcl-2 Interacting Protein with the Ability to Modulate Survival of Cancer Cells

(2010) Maria Teresa Vento et al.   PLoS One

THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death

(2009) Meenakshi P. Balakrishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Transcriptional dysregulation: a cause of dystonia?

(2009) Gen Tamiya   LANCET NEUROLOGY

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia

(2009) Tania Fuchs et al.   NATURE GENETICS

THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

(2009) Alex Sabogal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ronin Is Essential for Embryogenesis and the Pluripotency of Mouse Embryonic Stem Cells

(2008) Marion Dejosez et al.   CELL

Cell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc

(2008) C-Y Zhu et al.   CELL DEATH AND DIFFERENTIATION

Upregulation of Annexin A1 Expression by Butyrate in Human Colon Adenocarcinoma Cells: Role of p53, NF-Y, and p38 Mitogen-Activated Protein Kinase

(2008) E. Lecona et al.   MOLECULAR AND CELLULAR BIOLOGY

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE