Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes

The RNA Polymerase I Transcription Machinery: An Emerging Target for the Treatment of Cancer

(2010) Denis Drygin et al.   Annual Review of Pharmacology and Toxicology

Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

(2010) A. El Hage et al.   GENES & DEVELOPMENT

Yeast Pre-rRNA Processing and Modification Occur Cotranscriptionally

(2010) Martin Koš et al.   MOLECULAR CELL

Torsional regulation of hRPA-induced unwinding of double-stranded DNA

(2010) Iwijn De Vlaminck et al.   NUCLEIC ACIDS RESEARCH

Ribonuclease H: the enzymes in eukaryotes

(2009) Susana M. Cerritelli et al.   FEBS Journal

A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage

(2009) François-Michel Boisvert et al.   MOLECULAR & CELLULAR PROTEOMICS

In the absence of writhe, DNA relieves torsional stress with localized, sequence-dependent structural failure to preserve B-form

(2009) Graham L. Randall et al.   NUCLEIC ACIDS RESEARCH

The Paf1 complex is required for efficient transcription elongation by RNA polymerase I

(2009) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nuclear poly(A) polymerase and Exosome cofactor Trf5 is recruited cotranscriptionally to nucleolar surveillance

(2009) M. Wery et al.   RNA

Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics

(2009) Zhihua Li et al.   PLOS BIOLOGY

Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules

(2008) K. Merz et al.   GENES & DEVELOPMENT

Hypernegative Supercoiling Inhibits Growth by Causing RNA Degradation

(2008) I. Baaklini et al.   JOURNAL OF BACTERIOLOGY

Supercoiling and Local Denaturation of Plasmids with a Minimalist DNA Model

(2008) Fabio Trovato et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Transcription of Multiple Yeast Ribosomal DNA Genes Requires Targeting of UAF to the Promoter by Uaf30

(2008) R. D. Hontz et al.   MOLECULAR AND CELLULAR BIOLOGY

The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae

(2008) Brian Luke et al.   MOLECULAR CELL

Topoisomerase II Inactivation Prevents the Completion of DNA Replication in Budding Yeast

(2008) Jonathan Baxter et al.   MOLECULAR CELL

DNA torsional stress propagates through chromatin fiber and participates in transcriptional regulation

(2008) Christophe Lavelle   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The functional response of upstream DNA to dynamic supercoiling in vivo

(2008) Fedor Kouzine et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

(2008) Allyn J. Schoeffler et al.   QUARTERLY REVIEWS OF BIOPHYSICS