High-content Analysis of Antibody Phage-display Library Selection Outputs Identifies Tumor Selective Macropinocytosis-dependent Rapidly Internalizing Antibodies

Enhancing Chemotherapy Response with Sustained EphA2 Silencing Using Multistage Vector Delivery

(2013) H. Shen et al.   CLINICAL CANCER RESEARCH

Methods for site-specific drug conjugation to antibodies

(2013) Christopher R Behrens et al.   mAbs

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Antibody-Drug Conjugates in Cancer Therapy

(2012) Eric L. Sievers et al.   Annual Review of Medicine

Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors

(2012) Christina M. Annunziata et al.   INVESTIGATIONAL NEW DRUGS

Kaposi's sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection

(2012) S. Chakraborty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors

(2011) S. I. Rudnick et al.   CANCER RESEARCH

Trastuzumab Emtansine (T-DM1): A Novel Agent for Targeting HER2+ Breast Cancer

(2011) Howard A. Burris et al.   Clinical Breast Cancer

Structural and Functional Characterization of an Agonistic Anti-Human EphA2 Monoclonal Antibody

(2011) Li Peng et al.   JOURNAL OF MOLECULAR BIOLOGY

Sustained Small Interfering RNA Delivery by Mesoporous Silicon Particles

(2010) Takemi Tanaka et al.   CANCER RESEARCH

A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism

(2010) E. M. Reyes-Reyes et al.   CANCER RESEARCH

Emerging strategies for EphA2 receptor targeting for cancer therapeutics

(2010) Manish Tandon et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Internalizing Cancer Antibodies from Phage Libraries Selected on Tumor Cells and Yeast-Displayed Tumor Antigens

(2010) Yu Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of Internalizing Human Single-Chain Antibodies Targeting Brain Tumor Sphere Cells

(2010) X. Zhu et al.   MOLECULAR CANCER THERAPEUTICS

A Clathrin Independent Macropinocytosis-Like Entry Mechanism Used by Bluetongue Virus-1 during Infection of BHK Cells

(2010) Sarah Gold et al.   PLoS One

Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer

(2010) Helenia Ansuini et al.   Journal of Oncology

Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion

(2009) Fraser Conrad et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

(2009) Kenneth Smith et al.   Nature Protocols

A Human Antibody-Drug Conjugate Targeting EphA2 Inhibits Tumor Growth In vivo

(2008) D. Jackson et al.   CANCER RESEARCH

The EphA2 Receptor and EphrinA1 Ligand in Solid Tumors: Function and Therapeutic Targeting

(2008) J. Wykosky et al.   MOLECULAR CANCER RESEARCH

Targeted drug delivery to mesothelioma cells using functionally selected internalizing human single-chain antibodies

(2008) F. An et al.   MOLECULAR CANCER THERAPEUTICS