Article
Energy & Fuels
Nabil Amghar, Antonio Perejon, Carlos Ortiz, Luis A. Perez Maqueda, Pedro E. Sanchez-Jimenez
Summary: Long-term storage capability is an advantage of the calcium looping process. Experimental results show that storing solids at low temperatures does not substantially affect the multicycle performance, while storing them at high temperatures leads to easier heat integration, better plant efficiency, and higher energy density.
Article
Green & Sustainable Science & Technology
Zhixiong Ding, Wei Wu, Michael K. H. Leung
Summary: This study compares different absorption thermal battery cycles from various criteria perspectives, including energy storage efficiency, energy storage density, and exergy efficiency. The results show that the double-effect compression-assisted cycle can simultaneously improve energy storage efficiency and density and bridge the temperature gap. This is of great importance for achieving high-density and high-efficiency thermal energy storage.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2022)
Article
Oncology
Liang Pan, Xingyu Liu, Weidong Wang, Linhai Zhu, Wenfeng Yu, Wang Lv, Jian Hu
Summary: The study showed that in patients with T1 stage esophageal cancer, there was no difference in overall survival between non-esophagectomy and esophagectomy, but patients treated with non-esophagectomy had significantly better esophagus cancer specific survival.
FRONTIERS IN ONCOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Kokouvi Edem N'Tsoukpoe, Frederic Kuznik
Summary: This paper focuses on the challenges and questioning of long-term thermochemical heat storage for household applications, highlighting the significant thermal losses in seasonal thermochemical storage. The study suggests that the energy storage density based on solid hydrates or aqueous solutions may not be practical for long-term thermal energy storage for domestic hot water and heating.
RENEWABLE & SUSTAINABLE ENERGY REVIEWS
(2021)
Article
Biochemistry & Molecular Biology
Nghi M. Nguyen, Neetha N. Vellichirammal, Chittibabu Guda, Gurudutt Pendyala
Summary: This study investigates the potential impact of long-term exposure to midazolam (MDZ), a common benzodiazepine used as a sedative in the neonatal intensive care unit (NICU), on synaptic function. The results suggest that both short-term and long-term exposure to MDZ can lead to learning disturbances and perturb neurobehavioral outcomes at later stages of life.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Energy & Fuels
H. Rattez, F. Disidoro, J. Sulem, M. Veveakis
Summary: Velocity stepping experiments were conducted on simulated calcite gouge with dissolution, showing that dissolution leads to disappearance of small grains and a decrease in friction coefficient, promoting slip triggering but potentially reducing seismic potential.
GEOMECHANICS FOR ENERGY AND THE ENVIRONMENT
(2021)
Article
Polymer Science
Magdalena Krystyjan, Anna Dobosz-Kobedza, Marek Sikora, Hanna Maria Baranowska
Summary: This study investigated the effect of different concentrations of xanthan gum on the short- and long-term retrogradation of corn starch gels, and found that xanthan gum stabilized the starch in the short term, but did not inhibit retrogradation caused by amylopectin. The findings provide a possible mechanism for the retrogradation of corn starch.
Article
Engineering, Chemical
Abdullah Sadeq, Alexander Frank, Matthias Tyslik, Julian Jagers, Swantje Pietsch-Braune, Viktor Scherer, Stefan Heinrich
Summary: The water content of wood pellets has a significant impact on their stability. Exceeding a certain moisture level leads to pellet swelling and loss of stability. However, during drying, the pellets can recover their stability to a high degree, with high porosity pellets showing better long-term storage stability.
Article
Engineering, Biomedical
Johannes Windisch, Olena Reinhardt, Sarah Duin, Kathleen Schuetz, Nuria Juliana Novoa Rodriguez, Suihong Liu, Anja Lode, Michael Gelinsky
Summary: Bioprinting, a key technology for future space missions, is being established on the International Space Station (ISS). Researchers have investigated the storability of bioinks, aiming to produce bioinks on Earth and transport them to the ISS. The study shows that bioinks containing microalgae or human cells can be stored at 4 degrees C for four weeks without losing printability, but the viability of human cells decreases during storage. This research provides a promising starting point for future studies on storing bioinks and improving complex printing processes.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Environmental Sciences
Laela S. Sayigh, Vincent M. Janik, Frants H. Jensen, Michael D. Scott, Peter L. Tyack, Randall S. Wells
Summary: Common bottlenose dolphins produce individually distinctive signature whistles to recognize and maintain contact with conspecifics. These signature whistles show great variety in structure, but tend to be highly stereotyped and easily distinguishable. Studies have found that signature whistles have an unusually high capacity to convey information on individual identity.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Fisheries
Mariola A. Dietrich, Sylwia Judycka, Mariola Slowinska, Natalia Kodzik, Andrzej Ciereszko
Summary: This study investigated the impact of short-term storage on carp sperm proteome, revealing a decrease in sperm quality, increase in oxidative stress, and significant alterations in protein composition. The findings offer important insights into the mechanisms of sperm damage and potential protein markers for future research in aquaculture.
Article
Geography, Physical
Thomas Servais, Borja Cascales-Minana, David A. T. Harper, Bertrand Lefebvre, Axel Munnecke, Wenhui Wang, Yuandong Zhang
Summary: During the late Precambrian and early Cambrian, there was a gradual increase in the diversity of life, with the appearance of almost all animal phyla. However, there is no clear Cambrian explosion and Ordovician event, but rather a continuous and complex radiation of life throughout the Ordovician.
PALAEOGEOGRAPHY PALAEOCLIMATOLOGY PALAEOECOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ilitch Diaz-Gutierrez, Alexandria J. Robbins, Benjamin Zhang, Madhuri V. Rao, Amit Bhargava, Rafael S. Andrade
Summary: This study reviewed the midterm to long-term results of diaphragmatic hernia repair in patients who underwent sequential LVAD explantation and heart transplantation at the University of Minnesota since 1995. Among 21 patients who developed diaphragmatic hernia after heart transplantation, 16 underwent surgical repair with a 6.2% recurrence rate.
ANNALS OF THORACIC SURGERY
(2021)
Article
Energy & Fuels
Julian David Hunt, Behnam Zakeri, Andreas Nascimento, Jonas Rafael Gazoli, Fabio Tales Bindemann, Yoshihide Wada, Bas van Ruijven, Keywan Riahi
Summary: This paper presents a novel isothermal compressed air energy storage (CAES) system that uses two floating storage vessels in the deep ocean to balance the pressure with the oceanic pressure. The system has a maximum compression ratio of four, significantly increasing efficiency and reducing costs. The estimated cost for electric energy storage is between 10 and 50 USD/kWh, and for the installed power capacity is between 800 and 1500 USD/kW. It provides an alternative option for long-term energy storage in islands and coastal regions.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Cell Biology
Liangxia Ai, Yafei Li, Li Zhou, Wenrong Yao, Hao Zhang, Zhaoyu Hu, Jinyu Han, Weijie Wang, Junmiao Wu, Pan Xu, Ruiyue Wang, Zhangyi Li, Zhouwang Li, Chengliang Wei, Jianqun Liang, Haobo Chen, Zhimiao Yang, Ming Guo, Zhixiang Huang, Xin Wang, Zhen Zhang, Wenjie Xiang, Dazheng Sun, Lianqiang Xu, Meiyan Huang, Bin Lv, Peiqi Peng, Shangfeng Zhang, Xuhao Ji, Huiyi Luo, Nanping Chen, Jianping Chen, Ke Lan, Yong Hu
Summary: Lyophilized SARS-CoV-2 mRNA-lipid nanoparticle vaccines with long-term thermostability have been developed. These vaccines showed no change in physiochemical properties and bioactivities after being stored at 25 degrees C for 6 months. They elicited potent humoral and cellular immunity in animal models and humans, and significantly increased neutralizing antibody titers against specific variants.
Article
Biochemical Research Methods
Andrew R. Jones, Eric W. Deutsch, Juan Antonio Vizcaino
Summary: DIA proteomics techniques have made significant progress in recent years, but there is still room for improvement in terms of FAIR data principles. To enhance the current situation for DIA data, recommendations include developing an open data standard for spectral libraries, mandating the availability of spectral libraries in ProteomeXchange resources, improving support for DIA data in data standards, and enhancing support for DIA datasets in ProteomeXchange resources.
Article
Biochemical Research Methods
Ananth Prakash, David Garcia-Seisdedos, Shengbo Wang, Deepti Jaiswal Kundu, Andrew Collins, Nancy George, Pablo Moreno, Irene Papatheodorou, Andrew R. Jones, Juan Antonio Vizcaino
Summary: The availability of proteomics datasets, especially in the PRIDE database, has significantly increased in recent years, providing an opportunity for combined analyses of datasets to obtain organism-wide protein abundance data. In this study, we reanalyzed 24 public proteomics datasets to assess baseline protein abundance in 31 organs of healthy individuals. We compared protein abundances between organs, studied protein distribution, and performed gene ontology and pathway-enrichment analyses. The results are integrated into the Expression Atlas resource to enhance accessibility for life scientists.
JOURNAL OF PROTEOME RESEARCH
(2023)
Article
Biochemical Research Methods
Eric W. Deutsch, Juan Antonio Vizcaino, Andrew R. Jones, Pierre-Alain Binz, Henry Lam, Joshua Klein, Wout Bittremieux, Yasset Perez-Riverol, David L. Tabb, Mathias Walzer, Sylvie Ricard-Blum, Henning Hermjakob, Steffen Neumann, Tytus D. Mak, Shin Kawano, Luis Mendoza, Tim Van Den Bossche, Ralf Gabriels, Nuno Bandeira, Jeremy Carver, Benjamin Pullman, Zhi Sun, Nils Hoffmann, Jim Shofstahl, Yunping Zhu, Luana Licata, Federica Quaglia, Silvio C. E. Tosatto, Sandra E. Orchard
Summary: The Human Proteome Organization (HUPO) Proteomics Standards Initiative (PSI) has been developing guidelines and standards for the proteomics community for 20 years. The organization describes its operation, the current state of existing standards, and the proposals currently being developed. They emphasize the importance of community participation and collaboration with other organizations to promote data sharing and accelerate progress in proteomics.
JOURNAL OF PROTEOME RESEARCH
(2023)
Article
Biochemical Research Methods
Tobias G. Rehfeldt, Ralf Gabriels, Robbin Bouwmeester, Siegfried Gessulat, Benjamin A. Neely, Magnus Palmblad, Yasset Perez-Riverol, Tobias Schmidt, Juan Antonio Vizcaino, Eric W. Deutsch
Summary: Data set acquisition and curation are challenging in machine learning, particularly for proteomics-based LC-MS data sets due to data reduction. ProteomicsML is introduced as an online resource for accessing proteomics-based data sets and tutorials. It simplifies data access and provides tutorials for interacting with advanced algorithms. ProteomicsML enables comparison of machine learning algorithms and offers introductory material for newcomers in the field. The platform is freely available at https://www.proteomicsml.org/, and contributions are welcome at https://github.com/ProteomicsML/ProteomicsML.
JOURNAL OF PROTEOME RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Matthew Thakur, Alex Bateman, Cath Brooksbank, Mallory Freeberg, Melissa Harrison, Matthew Hartley, Thomas Keane, Gerard Kleywegt, Andrew Leach, Mariia Levchenko, Sarah Morgan, Ellen M. McDonagh, Sandra Orchard, Irene Papatheodorou, Sameer Velankar, Juan Antonio Vizcaino, Rick Witham, Barbara Zdrazil, Johanna McEntyre
Summary: EMBL-EBI is one of the world's leading sources of public biomolecular data, offering sustainable, high-quality data that can serve as training sets for deep learning and artificial intelligence applications. The open availability of their extensive curated databases makes them ideal for research in the life sciences.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Eric W. Deutsch, Nuno Bandeira, Yasset Perez-Riverol, Vagisha Sharma, Jeremy J. Carver, Luis Mendoza, Deepti J. Kundu, Shengbo Wang, Chakradhar Bandla, Selvakumar Kamatchinathan, Suresh Hewapathirana, Benjamin S. Pullman, Julie Wertz, Zhi Sun, Shin Kawano, Shujiro Okuda, Yu Watanabe, Brendan MacLean, Michael J. MacCoss, Yunping Zhu, Yasushi Ishihama, Juan Antonio Vizcaino
Summary: This article describes the recent developments in the ProteomeXchange (PX) consortium, which aims to standardize data submission and dissemination of MS proteomics data. The article highlights the increase in the number of datasets submitted to PX resources and the growing data re-use activities.
NUCLEIC ACIDS RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Yasmin Borutzki, Lukas Skos, Christopher Gerner, Samuel M. Meier-Menches
Summary: In recent years, metal-based candidate drugs have shown promise as modulators of cytoskeletal and cytoskeleton-associated proteins. Actin, vimentin, and plectin have been identified as targets of ruthenium(II) and platinum(II)-based modulators. However, there is limited structural information available on molecular interactions. This article compiles scattered reports on metal-based candidate molecules influencing the cytoskeleton and its associated proteins, exploring their potential in cancer-related processes.
Article
Biochemical Research Methods
Benjamin A. Neely, Viktoria Dorfer, Lennart Martens, Isabell Bludau, Robbin Bouwmeester, Sven Degroeve, Eric W. Deutsch, Siegfried Gessulat, Lukas Kaell, Pawel Palczynski, Samuel H. Payne, Tobias Greisager Rehfeldt, Tobias Schmidt, Veit Schwaemmle, Julian Uszkoreit, Juan Antonio Vizcaino, Mathias Wilhelm, Magnus Palmblad
Summary: In recent years, machine learning has made significant progress in modeling mass spectrometry data for proteomics analysis. A workshop was conducted to evaluate and explore machine learning applications in multidimensional mass spectrometry-based proteomics analysis. The workshop helped identify knowledge gaps, define needs, and discuss the possibilities, challenges, and future opportunities. The summary of the discussions conveys excitement about the potential of machine learning in proteomics and aims to inspire future research.
JOURNAL OF PROTEOME RESEARCH
(2023)
Article
Cell Biology
Huriye Ercan, Ulrike Resch, Felicia Hsu, Goran Mitulovic, Andrea Bileck, Christopher Gerner, Jae-Won Yang, Margarethe Geiger, Ingrid Miller, Maria Zellner
Summary: Proteomics is an essential analytical technique for studying biological systems using different proteins. The study compared the qualitative and quantitative performance of two commonly used proteomics techniques, label-free shotgun and 2D-DIGE, using six technical and three biological replicates of the human prostate carcinoma cell line DU145. The results showed that label-free shotgun quickly provides an annotated proteome but with reduced robustness compared to 2D-DIGE, which offers qualitative and quantitative information on proteoforms and post-translational modifications. However, the 2D-DIGE technique requires more time and manual work. Ultimately, this work highlights the different outputs and applications of these two techniques for biological research.
Article
Biochemistry & Molecular Biology
Franziska Ferk, Miroslav Misik, Benjamin Ernst, Gerhard Prager, Christoph Bichler, Doris Mejri, Christopher Gerner, Andrea Bileck, Michael Kundi, Sabine Langie, Klaus Holzmann, Siegfried Knasmueller
Summary: Obesity causes genetic instability, which is a key factor in the development of cancer and aging. This study investigated the effects of bariatric surgery on DNA repair, oxidative DNA damage, telomere lengths, antioxidant enzymes, and inflammation-related proteins. The results showed that after 6 months, bariatric surgery led to weight reduction, decreased DNA damage and oxidized DNA bases, lower levels of malondealdehyde, increased DNA repair and telomere lengths, and downregulation of inflammation-related proteins. These findings suggest that bariatric surgery can reduce DNA damage and inflammation, resulting in long-term health benefits.
Article
Biochemical Research Methods
Mathias Walzer, Kyowon Jeong, David L. Tabb, Juan Antonio Vizcaino
Summary: Although Top-down (TD) proteomics techniques are gaining popularity in intact protein and proteoform analysis, efforts are required to promote their adoption at different levels. Open science practices, including data sharing and open data analysis workflows, need to be improved and implemented.
Article
Cell Biology
Alexander Ries, Astrid Slany, Christine Pirker, Johanna C. C. Mader, Doris Mejri, Thomas Mohr, Karin Schelch, Daniela Flehberger, Nadine Maach, Muhammad Hashim, Mir Alireza Hoda, Balazs Dome, Georg Krupitza, Walter Berger, Christopher Gerner, Klaus Holzmann, Michael Grusch
Summary: In this study, novel hTERT-transduced mesothelial cell and Meso-CAF models were generated and characterized, and their impact on PM cell growth was investigated.
Article
Biochemistry & Molecular Biology
Nancy George, Silvie Fexova, Alfonso Munoz Fuentes, Pedro Madrigal, Yalan Bi, Haider Iqbal, Upendra Kumbham, Nadja Francesca Nolte, Lingyun Zhao, Anil S. Thanki, Iris D. Yu, Jose C. Marugan Calles, Karoly Erdos, Liora Vilmovsky, Sandeep R. Kurri, Anna Vathrakokoili-Pournara, David Osumi-Sutherland, Ananth Prakash, Shengbo Wang, Marcela K. Tello-Ruiz, Sunita Kumari, Doreen Ware, Damien Goutte-Gattat, Yanhui Hu, Nick Brown, Norbert Perrimon, Juan Antonio Vizcaino, Tony Burdett, Sarah Teichmann, Alvis Brazma, Irene Papatheodorou
Summary: Expression Atlas and Single Cell Expression Atlas are knowledgebases for gene and protein expression and localisation, covering bulk and single cell levels of data respectively. Users can search genes or metadata across species and explore data through dimensionality reduction plots and heatmaps to understand the expression patterns.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Mathematical & Computational Biology
Panni Simona, Kalpana Panneerselvam, Pablo Porras, Margaret Duesbury, Livia Perfetto, Luana Licata, Henning Hermjakob, Sandra Orchard
Summary: In this paper, the authors present a method of annotating microRNA-mRNA interactions from the scientific literature. They focus on microRNAs that regulate genes associated with rare diseases and provide a detailed description of cell types and experimental conditions to enhance the information about the interactions. The authors also highlight the importance of mapping the binding sites of microRNAs on target genes' mRNA transcripts.
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
(2023)