期刊
MODERN RHEUMATOLOGY
卷 25, 期 6, 页码 954-957出版社
SPRINGER
DOI: 10.3109/14397595.2013.844403
关键词
APLS; Anakinra; Macrophage activation syndrome; PET-CT; SLE
类别
A patient with antiphospholipid syndrome, SLE and refractory fever is described. The cause for the fever was macrophage activation syndrome (MAS). The diagnosis of MAS was made with the help of PET-CT. Since the syndrome was refractory to conventional therapy with high-dose steroids and cyclosporin, anakinra was administered with complete recovery of the patient. The present case illustrates the difficulties in diagnosing MAS when multiple bone marrow biopsies fail to show hemophagocytosis. It emphasizes the significance of PET-CT in the diagnosis and evaluation of treatment of MAS. Finally, it describes the important role of Anakinra in treating refractory cases of MAS.
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