期刊
MITOCHONDRION
卷 13, 期 6, 页码 846-851出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.mito.2013.06.001
关键词
mtDNA; Primates; Positive selection
资金
- Conselho Nacional de Desenvolvimento (CNPq) [303306/2010-6]
- Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ) [E26/103.012/2011]
- FAPERJ/CAPES from Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro [E26/102.810/2011]
- Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES-Brazil)
The mitochondrial genomes of four neotropical primates, Aotus infulatus, Chiropotes israelita, Callimico goeldii and Callicebus lugens were sequenced and annotated. Phylogenetic reconstructions with mitochondrial genes of other 66 primates showed a similar arrangement to a topology based on nuclear genes. Screening for positive selection identified 15 codons in 7 genes along 9 independent lineages, three with two or more genes and five in internal nodes, ruling out false positive estimates. Mitochondrial genes of the electron transport chain (ETC.) complexes evolved with high substitution rates. A study of nuclear ETC. genes might elucidate whether they co-evolved with their mitochondrial counterparts. (C) 2013 Elsevier B.V. and Mitochondria Research Society. All rights reserved.
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