Article
Engineering, Marine
Bo Liu, Yali Yan, Nan Zhang, Huayang Guo, Baosuo Liu, Jingwen Yang, Kecheng Zhu, Dianchang Zhang
Summary: Species markers can be assessed quickly and accurately using DNA barcoding. In this study, we used DNA barcoding to investigate the parrotfish family Scaridae in Hainan, and found that DNA barcoding can be an effective tool for monitoring, protecting, and managing fisheries, as well as for addressing taxonomic issues.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Biotechnology & Applied Microbiology
Qian Tang, Q. Luo, Qian Duan, Lei Deng, Renyi Zhang
Summary: This study conducted in Guiyang, Guizhou Province, China, revealed the presence of commercial fraud in fish products, with a significant percentage of samples being inconsistent with their labels. The use of DNA barcoding was shown to be an effective tool for identifying mislabeled fish products and potentially enhancing transparency and fair trade in domestic fisheries.
JOURNAL OF FOOD PROTECTION
(2022)
Article
Food Science & Technology
Bo Liu, Jing-Wen Yang, Bao-Suo Liu, Nan Zhang, Liang Guo, Hua-Yang Guo, Dian-Chang Zhang
Summary: This study used DNA barcoding to identify fish species in Guangzhou supermarkets and sushi restaurants, and found that a significant proportion of the products were mislabeled or had insufficient information on the label, indicating a need for improved global regulation of fish product labeling.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Entomology
Wolfgang Paill, Stephan Koblmueller, Thomas Friess, Barbara-Amina Gereben-Krenn, Christian Mairhuber, Michael J. Raupach, Lukas Zangl
Summary: The study provides the first reliable record of Pterostichus adstrictus in the Austrian Alps, confirming its southernmost distribution edge. Further research demonstrates the seasonal occurrence and habitat preferences of P. adstrictus in the region.
Article
Marine & Freshwater Biology
Sara M. Francisco, Cristina S. Lima, Ines Moreira, Adel A. Basyouny Shahin, Abderraouf Ben Faleh
Summary: This study established a reference library for commercially important marine fish species along the Tunisian coast using DNA barcoding. The results confirmed the effectiveness of the barcode approach in species identification and provided valuable information for the monitoring, conservation, and management of fisheries.
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM
(2022)
Review
Zoology
Cheng-Qi Zhu, Xiao-Dong Xu, Ying Zhen
Summary: The Luciolinae genus Emeia was studied and classified in this research. Phylogenetic analysis based on DNA barcoding sequences determined the classification of Emeia genus and revealed a new species. A key for identifying Emeia species using males is provided in the article.
Article
Ecology
Lijuan Wang, Zhihao Wu, Guiqing Sun, Hui Chen, Hongjun Liu, Feng You
Summary: This study conducted DNA barcoding analysis on 309 fish species in Chinese coastal waters, confirming that DNA barcoding is a reliable method for fish species identification. The establishment of a barcode library will facilitate the monitoring and management of marine fishery resources in China.
REGIONAL STUDIES IN MARINE SCIENCE
(2022)
Article
Zoology
Chengqi Zhu, Xiaodong Xu, Ying Zhen
Summary: Two new species of the genus Pyrocoelia were described from Mt. Cenwanglaoshan of Guangxi, Southwest China. These new species were distinguished from other known species based on external morphological characters and male genitalia. In addition, the distribution of Pyrocoelia species in China was summarized.
Article
Biodiversity Conservation
Rodrigue Orobiyi Edeya Pelebe, Ibrahim Imorou Toko, Erik Verheyen, Maarten Van Steenberge
Summary: The study revealed that the population of Sarotherodon melanotheron in the Atchakpa reservoir may have resulted from a natural range extension within Benin. The subspecies S. m. melanotheron has also been previously introduced in the Philippines. Further research is necessary to investigate the socioeconomic, ecological, and environmental impacts of this species in the reservoir.
Article
Biodiversity Conservation
Nikolaus Helmer, Christoph Hoerweg, Helmut Sattmann, Susanne Reier, Nikolaus U. Szucsich, Jana Bulantova, Elisabeth Haring
Summary: We developed and evaluated species-specific PCR primers for detecting Trichobilharzia species using eDNA barcoding in Austrian water bodies. The primers successfully identified T. szidati and T. physellae from both field eDNA samples and lab-generated samples. However, there was considerable variation in replicate results. PCR tests on aquarium water, where cercariae had been released, still detected eDNA even after 44 days. Sensitivity tests showed successful amplification down to concentrations of 0.83 pg/mu L and 0.008 pg/mu L for genomic DNA and PCR products of T. szidati, respectively. The study highlights the potential misidentification risks associated with presumed species-specific PCR primers.
Article
Zoology
David Selnekovic, Katarina Goffova, Jan Soltys, Eva Kovacova, Jan Kodada
Summary: The study describes a new species of Mordellistena (s. str.) platypoda found on the island of Ischia in Italy, based on morphological characters and genetic analysis. The analysis shows that M. platypoda is closely related to M. tarsata, but they differ significantly in vestiture colouration, presence of lateral ctenidia on the third metatarsomere, and presence of sexual dimorphism on the protibia. Interestingly, the new species is currently known only from Ischia and no additional specimens were found in museum material.
Article
Microbiology
Mikel Alexander Gonzalez, Daniel Bravo-Barriga, Maria Altagracia Rodriguez-Sosa, Juan Rueda, Eva Frontera, Pedro Maria Alarcon-Elbal
Summary: This study assessed the occurrence and blood meal sources of biting dipteran species in different habitats in the Dominican Republic using CDC downdraft suction traps with UV light. A total of 18 mosquito species, 6 Culicoides species, 2 black fly species, and 1 muscid fly species were identified. The results showed that engorged mosquitoes and Culicoides females had host preferences for mammals, except for Culex species which had blood from chickens. The study also provided new records for the Dominican dipteran catalogue, COI DNA sequences in GenBank, diagnostic feature pictures, spatial distribution, and feeding preferences in the Caribbean region.
Article
Environmental Sciences
Yawen Mu, Chao Song, Jianghua Yang, Yong Zhang, Xiaowei Zhang
Summary: This study used DNA barcoding to identify species and assess biodiversity of fish in Tai Lake. High-throughput sequencing greatly improved the capture rate of barcode sequences of fish, and barcode gap analysis successfully delineated species in all specimens. The results are expected to provide new insights into fish diversity conservation in Tai Lake.
Article
Multidisciplinary Sciences
Jeganathan Pandiyan, Arun Zachariah, Bathrachalam Chandramohan, Shahid Mahboob, Khalid A. Al-Ghanim, Zaib-Un-Nisa, Marcello Nicoletti, Marimuthu Govindarajan
Summary: This study used cytochrome c oxidase I (COI) to analyze the DNA barcodes and assess the relationship among waterbird species. The phylogenetic tree and sequence alignment of COI revealed genetic differences and conserved haplotypes among the species.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Veterinary Sciences
Luis M. Hernandez-Triana, Javier A. Garza-Hernandez, Aldo Ortega Morales, Sean W. J. Prosser, Paul D. N. Hebert, Nadya Nikolova, Elsa Barrero, Erick de J. de Luna-Santillana, Vicente H. Gonzalez-Alvarez, Ramon Mendez-Lopez, Rahuel J. Chan-Chable, Anthony R. Fooks, Mario A. Rodriguez-Perez
Summary: This study in Mexico analyzed mosquito feeding preferences and blood meal sources from RNA extracts, identifying multiple organisms from a single extract for the first time. A total of 1,634 mosquito specimens were collected, with four new species records for Mexico and nine new records for Chiapas State. High intraspecific divergence values were observed in certain taxa, and blood meal analysis revealed feeding preferences of different mosquito species.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Chemistry, Medicinal
Ellen Watts, David Heidenreich, Elizabeth Tucker, Monika Raab, Klaus Strebhardt, Louis Chesler, Stefan Knapp, Benjamin Bellenie, Swen Hoelder
JOURNAL OF MEDICINAL CHEMISTRY
(2019)
Article
Oncology
Monika Raab, Mourad Sanhaji, Shengtao Zhou, Franz Roedel, Ahmed El-Balat, Sven Becker, Klaus Strebhardt
Article
Oncology
Monika Raab, Nene F. Kobayashi, Sven Becker, Elisabeth Kurunci-Csacsko, Andrea Kraemer, Klaus Strebhardt, Mourad Sanhaji
INTERNATIONAL JOURNAL OF CANCER
(2020)
Article
Multidisciplinary Sciences
Monika Raab, Klaus Strebhardt, Christopher E. Rudd
SCIENTIFIC REPORTS
(2019)
Article
Oncology
Max Fleischmann, Daniel Martin, Samuel Pena-Llopis, Julius Oppermann, Jens von der Gruen, Markus Diefenhardt, Georgios Chatzikonstantinou, Emmanouil Fokas, Claus Roedel, Klaus Strebhardt, Sven Becker, Franz Roedel, Nikolaos Tselis
FRONTIERS IN ONCOLOGY
(2019)
Article
Multidisciplinary Sciences
Youg Raj Thaker, Monika Raab, Klaus Strebhardt, Christopher E. Rudd
NATURE COMMUNICATIONS
(2019)
Review
Biochemistry & Molecular Biology
Ranadip Mandal, Joan Compte Barron, Izabela Kostova, Sven Becker, Klaus Strebhardt
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
(2020)
Review
Oncology
Izabela Kostova, Ranadip Mandal, Sven Becker, Klaus Strebhardt
Summary: Caspase-8, a key regulator in multiple signaling pathways, not only controls cell cycle and behavior but also immune response and cytokine production within the tumor microenvironment. Dysregulated expression of caspase-8 in ovarian cancer influences tumor aggressiveness and immune resistance, highlighting its potential as a therapeutic target for developing new treatment strategies against the complex tumor microenvironment.
CANCER AND METASTASIS REVIEWS
(2021)
Review
Cell Biology
Monika Kressin, Daniela Fietz, Sven Becker, Klaus Strebhardt
Summary: Polo-like kinases (PLKs) are a group of highly conserved serine/threonine kinases that play crucial roles in tumorigenesis, particularly with the overexpression of PLK1 being associated with poor prognosis in different cancers. Current research is focusing on investigating the multiple functions of PLKs and their potential as cancer targets, with a specific emphasis on PLK1 and PLK4 inhibition in various cancer trials.
Article
Oncology
Monika Raab, Marcel Rak, Roberta Tesch, Khayal Gasimli, Sven Becker, Stefan Knapp, Klaus Strebhardt, Mourad Sanhaji
Summary: The study found that MRIA9 enhances the efficacy of paclitaxel in eliminating ovarian cancer cells and inhibits the activity of SIK2, leading to abnormal mitosis. Additionally, MRIA9 increases sensitivity to paclitaxel, suggesting selective targeting of SIK2 in ovarian cancer as a potential therapeutic strategy for overcoming paclitaxel resistance.
Article
Biochemistry & Molecular Biology
Monika Raab, Yves Matthess, Christopher A. Raab, Niklas Gutfreund, Volker Doetsch, Sven Becker, Mourad Sanhaji, Klaus Strebhardt
Summary: PLK1 activation during the G2 phase is controlled by dimerization supported by Bora and dissociation triggered by Aurora-A phosphorylation, allowing timely entry into mitosis. Interfering with this dimer/monomer switch affects PLK1's nuclear shuttling and localization during the G2-M transition, suggesting potential for novel PLK1 inhibitors.
Review
Oncology
Maximilian Fleischmann, Georgios Chatzikonstantinou, Emmanouil Fokas, Jorn Wichmann, Hans Christiansen, Klaus Strebhardt, Claus Roedel, Nikolaos Tselis, Franz Roedel
Summary: Despite advancements in screening and vaccination programs, uterine cervical cancer remains a leading cause of cancer-related mortality in women worldwide. New therapeutic approaches have not significantly improved treatment response and prognosis, highlighting the urgent need for robust molecular markers to predict therapy response and clinical outcome.
Article
Biochemistry & Molecular Biology
Khayal Gasimli, Monika Raab, Morva Tahmasbi Rad, Elisabeth Kurunci-Csacsko, Sven Becker, Klaus Strebhardt, Mourad Sanhaji
Summary: This study found that amplification of KRAS may be the underlying cause of PARPi resistance in BRCA2-deficient high-grade serous ovarian cancer (HGSOC). Inhibition of PLK1 has shown to restore sensitivity to PARPi in KRAS-amplified HGSOC and enhance the cellular apoptotic response to carboplatin-based chemotherapy. These findings shed new light on the role of PLK1 in reversing PARPi resistance and offer a potential therapeutic strategy for ovarian cancer patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Oncology
Maximilian Fleischmann, Ranadip Mandal, Izabela Kostova, Monika Raab, Mourad Sanhaji, Stephanie Hehlgans, Markus Diefenhardt, Claus Roedel, Emmanouil Fokas, Klaus Strebhardt, Franz Roedel
Summary: Elevated levels of caspase-8 and CDK9 are associated with improved outcomes in cervical cancer patients treated with primary platinum-based chemoradiation, while higher levels of phosphorylated CDK9 predict worse survival. Biomarker research can help improve treatment strategies for cervical cancer patients.
Correction
Biochemistry & Molecular Biology
Monika Raab, Yves Matthess, Christopher A. Raab, Niklas Gutfreund, Volker Doetsch, Sven Becker, Mourad Sanhaji, Klaus Strebhardt