Article
Neurosciences
Piaoliu Yuan, Zhouhui Lian, Yuanyuan Wang, Chunyu Zhang, Hongfang Jin, Junbao Du, Yaqian Huang, Ying Liao
Summary: This study investigates the use of Poincare plot in predicting the curative effect of metoprolol for pediatric POTS. The results suggest that a T < 573.9 ms combined with an L/T > 2.9 in the Poincare plot can help predict the effectiveness of metoprolol treatment.
FRONTIERS IN NEUROSCIENCE
(2023)
Review
Endocrinology & Metabolism
Huamin Zeng, Ying Zhang, Sikai Huang, Jinghua Wu, Wenrui Ren, Lingru Zhou, Leneng Huang, Yuyin Ye
Summary: Metformin combined with spironolactone therapy may be more effective in reducing BMI and serum androgen levels in PCOS patients. However, it does not have a significant effect on hirsutism score or gonadotropin hormone levels, and is not associated with an elevation in side-effects. When the treatment course is greater than 6 months, combination therapy can effectively reduce FBG and improve insulin resistance.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Education & Educational Research
Irem Demirbas, Ayfer Sahin
Summary: This study aimed to investigate the impact of digital stories on the creative writing abilities of fourth-grade primary school students. A quasi-experimental research model with a pretest-posttest control group was employed in the study, which took place in Sanliurfa, Turkey during the second semester of the 2018-2019 academic year. The results showed that digital stories significantly improved the creative writing scores of the students in the experimental group compared to the control group, indicating that the digital story intervention was more effective than a paper-based approach.
EDUCATION AND INFORMATION TECHNOLOGIES
(2023)
Article
Rheumatology
Wei Lin, Zhifei Xin, Xiaoran Ning, Yang Li, Xiuying Ren, Yashuang Su, Meilu Liu, Shaoying Guo, Liu Yang, Yixuan Liu, Fengxiao Zhang, Wen Zhang
Summary: The study aimed to investigate RP in pSS patients, finding that pSS patients with RP were younger, had higher disease activity, and higher prevalence of lung involvement. Furthermore, they had higher positivity rates for ANA, anti-RNP, and ACA antibodies. Lung involvement, anti-RNP positivity, and ACA were identified as prognostic factors for pSS-RP.
CLINICAL RHEUMATOLOGY
(2021)
Article
Medicine, General & Internal
Maria Maddalena Sirufo, Lina Maria Magnanimi, Lia Ginaldi, Massimo De Martinis
Summary: Raynaud's phenomenon is a common clinical finding that can be distinguished using nailfold videocapillaroscopy. However, the variety of nomenclature and the presence of non specific vascular changes make it difficult to differentiate different types of Raynaud's phenomenon.
CURRENT MEDICAL RESEARCH AND OPINION
(2022)
Article
Cardiac & Cardiovascular Systems
Li-Jun Liu, Guo-Hua Zhu, Hong-Yu Luo, Xi-Peng Sun, Jing Li, Qi Hua
Summary: The combination of Tongmai Yangxin Pill (TMYXP) and metoprolol tartrate showed greater efficacy in reducing the frequency of premature ventricular complex (PVC) and relieving PVC-related symptoms compared to metoprolol tartrate alone. It also improved cardiac function in patients with symptomatic PVC.
JOURNAL OF GERIATRIC CARDIOLOGY
(2022)
Review
Medicine, General & Internal
Gjin Ndrepepa, Adnan Kastrati
Summary: Coronary no-reflow (CNR) is a common occurrence in patients with ST-segment elevation myocardial infarction (STEMI) after reperfusion therapy. It is caused by microvascular obstruction (MVO) resulting from myocardial ischemia, distal embolization, and reperfusion-related injury. Currently, there is no therapy that consistently prevents or reverses CNR and provides clinical benefit in STEMI patients undergoing reperfusion.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biology
Maria Maddalena Sirufo, Alessandra Catalogna, Francesca De Pietro, Lia Ginaldi, Massimo De Martinis
Summary: Drummers are at risk of microvascular abnormalities and Raynaud's phenomenon due to prolonged exposure to vibration. Nailfold video capillaroscopy is a useful tool for detecting and monitoring these issues with low cost and high sensitivity.
Review
Integrative & Complementary Medicine
Fangwen Zhou, Emma Huang, Elena Zheng, Jiawen Deng
Summary: This study evaluated the effectiveness of acupuncture for the treatment of Raynaud's syndrome through a systematic review and meta-analysis. The results suggest that acupuncture may increase remission incidence, decrease daily number of attacks, and increase incidences of positive cold stimulation tests. However, due to small sample sizes, low quality of evidence, and high risk of bias, larger randomized controlled trials are needed to confirm these findings.
ACUPUNCTURE IN MEDICINE
(2023)
Article
Endocrinology & Metabolism
Qing Wen, Song Fang, Yanjing Liang, Yuting Tian, Yiding Chen, Jun Yuan, Qiu Chen
Summary: This study aimed to observe the effect of beinaglutide combined with metformin versus metformin alone on weight loss and metabolic profiles in obese patients with polycystic ovary syndrome. The results showed that the combined treatment was more effective in reducing weight, body mass index, waist circumference, and waist to height ratio compared to metformin monotherapy.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Rheumatology
Daniel Ennis, Zareen Ahmad, Melanie A. Anderson, Sindhu R. Johnson
Summary: This article reviews the effectiveness of botulinum toxin injections in treating Raynaud's phenomenon and discusses formulations, dosages, administration sites, and adverse effects. The evidence for botulinum toxin in the treatment of Raynaud's phenomenon is promising, but further research is needed to ensure consistency in treatment outcomes across different patient populations and treatment options.
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
(2021)
Article
Obstetrics & Gynecology
Marissa Steinberg Weiss, Andrea Hsu Roe, Kelly C. Allison, William C. Dodson, Penny M. Kris-Etherton, Allen R. Kunselman, Christy M. Stetter, Nancy I. Williams, Carol L. Gnatuk, Stepanie J. Estes, David B. Sarwer, Christos Coutifaris, Richard S. Legro, Anuja Dokras
Summary: The study found a high prevalence of female sexual dysfunction among women with PCOS, but lifestyle intervention and the combined treatment of lifestyle intervention and oral contraceptive pills can improve sexual function in these patients, especially in terms of sexual desire.
FERTILITY AND STERILITY
(2021)
Article
Health Care Sciences & Services
Linda C. Hendriksen, Grace Omes-Smit, Birgit C. P. Koch, M. Arfan Ikram, Bruno H. Stricker, Loes E. Visser
Summary: Women using Metoprolol have a higher risk of bradycardia and a lower heart rate compared to men, possibly due to higher plasma concentration of the drug.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Rehabilitation
Musa Sani Danazumi, Shehu Usman Ibrahim, Abdulsalam Mohammed Yakasai, Gordana Dermody, Bashir Bello, Bashir Kaka
Summary: The study concludes that both Kinesio taping + combined chain exercises and combined chain exercises were effective in managing individuals with knee osteoarthritis, with the former showing superior effectiveness.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2021)
Article
Pharmacology & Pharmacy
Fangfang Miao, Kunpeng Feng, Xuexin Feng, Long Fan, Yu Lang, Qingfang Duan, Ruixue Hou, Di Jin, Tianlong Wang
Summary: This study investigated the optimal concentrations of ropivacaine and sufentanil for controlling postoperative pain after cesarean section. The results showed that the combination of 0.15% ropivacaine and 0.5 mu g/ml sufentanil administered epidurally led to lower pain scores, improved patient satisfaction, and shorter time to first flatus, but also increased the incidence of pruritus and numbness.
FRONTIERS IN PHARMACOLOGY
(2021)
Letter
Otorhinolaryngology
Amir H. Shemirani
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2016)
Article
Medicine, Research & Experimental
Nora Homorodi, Emese G. Kovacs, Sarolta Lee, Eva Katona, Amir H. Shemirani, Gizella Haramura, Laszlo Balogh, Zsuzsanna Bereczky, Gabriella Szoke, Hajna Peterfy, Robert G. Kiss, Istvan Edes, Laszlo Muszbek
JOURNAL OF TRANSLATIONAL MEDICINE
(2016)
Letter
Hematology
G. Kecskemetine, Z. Csiki, M. Mile, K. S. Zsori, A. H. Shemirani
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
(2017)
Review
Cell Biology
Sandor Kovacs, Zoltan Csiki, Katalin S. Zsori, Zsuzsanna Bereczky, Amir H. Shemirani
Letter
Hematology
Edit Szomjak, Zoltan Csiki, Kalatalin Szilvia Zsori, Csilla Andras, Amir-Houshang Shemirani
BLOOD COAGULATION & FIBRINOLYSIS
(2013)
Article
Hematology
Amir-Houshang Shemirani, Balint Antalfi, Endre Pongracz, Zoltan Andras Mezei, Zsuzsanna Bereczky, Zoltan Csiki
BLOOD COAGULATION & FIBRINOLYSIS
(2014)
Article
Hematology
E. Katona, L. Muszbek, K. Devreese, K. B. Kovacs, Z. Bereczky, M. Jonkers, A. H. Shemirani, V. Mondelaers, A. A. M. Ermens
Article
Cardiac & Cardiovascular Systems
Katalin S. Zsori, Zoltan Csiki, Eva Katona, Zsuzsnna Bereczky, Amir-Houshang Shemirani
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2013)
Article
Rheumatology
Alajos-Tamas Takats, Amir-Houshang Shemirani, Katalin-Szilvia Zsori, Csilla Andras, Zoltan Csiki
RHEUMATOLOGY INTERNATIONAL
(2013)
Article
Biochemistry & Molecular Biology
Zsuzsanna Z. Orosz, Helga Bardos, Amir H. Shemirani, Ildiko Beke Debreceni, Riitta Lassila, Antti S. Riikonen, Johanna A. Kremer Hovinga, Theo G. Seiler, Hendrika A. van Dorland, Verena Schroeder, Zoltan Boda, Laszlo Nemes, Beatrice Frueh Eppstein, Bence Nagy, Andrea Facsko, Janos Kappelmayer, Laszlo Muszbek
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Review
Cell Biology
Farzaneh Sadeghi, Sandor Kovacs, Katalin Szilvia Zsori, Zoltan Csiki, Zsuzsanna Bereczky, Amir Houshang Shemirani
Article
Health Care Sciences & Services
Farzaneh Sadeghi, Ferenc Sarkady, Katalin S. Zsori, Istvan Szegedi, Rita Orban-Kalmandi, Edina G. Szekely, Nikolett Vasas, Ervin Berenyi, Laszlo Csiba, Zsuzsa Bagoly, Amir H. Shemirani
Summary: This study demonstrated for the first time that a high NLR-low LMR combination observed at 24 hours after thrombolysis can serve as an independent predictor of poor 3-months outcome in acute ischemic stroke patients. This simple and readily available data may help clinicians to improve the prognostic estimation of patients and may provide guidance in selecting patients for personalized and intensified care post-thrombolysis.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Environmental Sciences
Balazs Fabian, Ildiko Fanny Horvath, Amir Houshang Shemirani, Zoltan Csiki
Summary: The study showed positive correlation of mean platelet volume (MPV) with anxiety and depression, and negative correlation of platelet distribution width (PDW) with anxiety and depression. Logistic regression analysis revealed significant association of MPV with both depression and anxiety.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Chemistry, Multidisciplinary
Gabriella Kecskemetine, Katalin Szilvia Zsori, Sandor Komives, Maria Sohajda, Zoltan Csiki, Janos Matyus, Laszlo Ujhelyi, Jozsef Balla, Attila Nagy, Amir Houshang Shemirani
Summary: This study aimed to investigate the association between chronic kidney disease (CKD) and rs11959928, rs626277, and rs7805747 polymorphisms, and compared the findings between male and female patients and controls. The results showed that these genetic variants have different effects in males and females. Therefore, further studies in larger cohorts are needed.
APPLIED SCIENCES-BASEL
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
L. Muszbek, N. Homorodi, E. G. Kovacs, E. Katona, Z. Bereczky, L. Balogh, A. G. Shemirani, H. Peterfy, R. G. Kiss, I. Edes
Article
Peripheral Vascular Disease
Jingting Yao, Justin D. Sprick, Jinhee Jeong, Jeanie Park, David A. Reiter
Summary: This study used time-frequency spectral analysis of resting near-infrared spectroscopy (NIRS) signals to evaluate the regulation of peripheral microvascular perfusion in CKD patients. The findings suggest that CKD patients have impaired neurogenic and endothelial functions, which may be associated with increased sympathetic activity and reduced endothelial function in CKD.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Yoh Sugawara, Yusuke Mizuno, Shinya Oku, Yuri Sawada, Takahisa Goto
Summary: This study investigated the role of Protein kinase D (PKD) in aortic contraction and hemodynamics, finding that PKD1 plays a crucial role in these processes through phosphorylation of MYPT1 and actin polymerization in a calcium-independent manner.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Xuenan Zhuang, Guiqin He, Yunkao Zeng, Miaoling Li, Yongyue Su, Xuelin Chen, Yining Zhang, Yuhong Gan, Feng Wen, Xiongze Zhang
Summary: This study assessed the impact of acute, heavy alcohol consumption on the ocular microvasculature. The findings suggest that excessive alcohol consumption leads to vasoconstriction in ocular arterioles and vasodilation in capillaries, particularly evident 1-hour post-consumption.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Ayuki Nakano, Akane Morita, Shiho Arima, Tohru Nagamitsu, Tsutomu Nakahara
Summary: This study examines the preventative and therapeutic effects of inhibiting mammalian target of rapamycin complex 1 (mTORC1) on abnormal retinal blood vessels in a rat model of retinopathy of prematurity (ROP). The results suggest that mTORC1 activation in proliferating endothelial cells contributes to the appearance and progression of ROP-like retinal blood vessels. Inhibition of mTORC1 may be a promising approach for selectively targeting abnormal retinal blood vessels in ROP.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Bing Wang, Xiaohong Song, Xu Zhang, Yuan Li, Mengting Xu, Xueting Liu, Bingwei Li, Sunjing Fu, Hao Ling, Yingyu Wang, Xiaoyan Zhang, Ailing Li, Mingming Liu
Summary: This study found that glycine supplementation can improve pancreatic microcirculation in T1DM mice and reverse the production of inflammatory cytokines. Furthermore, glycine supplementation also alleviates damage to pancreatic islet and vascular tissues, suggesting a potential therapeutic effect for T1DM.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Merve Erkisa Genel, Kaan Adacan, Selin Selvi, Deniz Erol Kutucu, Ayca Uvez, Elif Ilkay Armutak, Abdurrahman Sengul, Engin Ulukaya, Ebru Gurel Gurevin
Summary: This study investigated the anti-growth/cytotoxic effect of a dinuclear Pd(II) complex on breast cancer cell lines and confirmed its anti-migration and antiangiogenic properties. The results suggest the potential of this complex in the treatment of breast cancer.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Cedric Mueller, Christoph Hauser, Justin Carrard, Konstantin Gugleta, Timo Hinrichs, Arno Schmidt-Trucksass, Henner Hanssen, Lukas Streese
Summary: This study aimed to evaluate the differences in microvascular health between normotensive individuals and patients with arterial hypertension and to assess the effects of short-term high-intensity interval training (HIIT) on microvascular health in patients with arterial hypertension. The study found that short-term HIIT can ameliorate hypertension-induced retinal microvascular abnormalities in patients with arterial hypertension.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Yuyang Hou, Wenjing Du, Qiong Wu, Xinyu Chai, Yinan Wang, Yingqian Mi, Yuan Tian, Mengyan Tang, Jun Li, Dongmei Yan
Summary: This study identified a prognostic signature consisting of four genes in bladder cancer patients and utilized angiogenesis-related genes and molecular subtypes to construct this signature, which could help predict survival outcomes. The study also evaluated immune cell infiltration and predicted chemotherapeutic responses, confirming the effectiveness of this prognostic signature.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Sean D. Mcgarry, Cynthia Adjekukor, Suchit Ahuja, Jasper Greysson-Wong, Idy Vien, Kristina D. Rinker, Sarah J. Childs
Summary: The article introduces a software tool called Vessel Metrics for analyzing developmental vascular microscopy images, which can expedite the analysis process and ensure consistency between research groups. The tool includes a segmentation algorithm that accurately quantifies different image types and has been validated in zebrafish and mouse models.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Y. P. Latul, C. Ince, N. E. van Trommel, A. van den Brandhof-van den Berg, J. P. W. R. Roovers, A. W. Kastelein
Summary: This study evaluated the real-time detection capability of handheld vital microscopy (HVM) for cervical intraepithelial neoplasia (CIN) and cervical cancer (CC). The results showed that HVM enables easy, real-time, and non-invasive assessment of cervical lesions through the detection of microvascular alterations. This method has the potential to be used for point-of-care screening, reducing unnecessary surgical interventions.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Zhifei Liu, Jieqiong Zhang, Xue Li, Qiumei Hu, Xi Chen, Linlin Luo, Liqianyu Ai, Jian Ye
Summary: The study revealed that astrocytic YAP can alleviate retinal pathological angiogenesis by inhibiting overactivation of astrocytes, thereby suppressing excessive VEGF-A production and neuroinflammation.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Robert G. Hahn
Summary: The fast-exchange interstitial fluid compartment is directly connected to the circulating blood, while the slow-exchange compartment is not.
MICROVASCULAR RESEARCH
(2024)
Review
Peripheral Vascular Disease
Nadia Hamjane, Mohcine Bennani Mechita, Naima Ghailani Nourouti, Amina Barakat
Summary: Gut microbiota dysbiosis plays a crucial role in the development of obesity-related metabolic abnormalities, including insulin resistance, type 2 diabetes, and cardiovascular diseases. Inflammation is a major mechanism linking gut microbiota dysbiosis to obesity-associated metabolic complications.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Guangzhen Zhou, Yan Gao, Yanbin Shi, Shengnan Qiu, Guimei Lin, Xinbing Ding, Wenguang Wang, Yihua Feng, Fei Wang, Jinwei Qiao
Summary: This study utilized an in vitro biomimetic experimental system to investigate the transvascular transport of nano-preparations, and found that the pressure gradient between vascular fluid pressure and interstitial fluid pressure determines the existence of the enhanced penetration and retention effect of nanopreparations.
MICROVASCULAR RESEARCH
(2024)
Article
Peripheral Vascular Disease
Kenji Chamoto, Barry C. Gibney, Willi L. Wagner, Maximilian Ackermann, Hassan A. Khalil, Steven J. Mentzer
Summary: In the study, the process of angiogenesis in adult regenerating tissue was investigated by grafting portions of the regenerating lung onto the chick chorioallantoic membrane. The results showed peri-graft angiogenesis, particularly in the cardiac lobe. Functional vascular connections were observed between the cardiac lobe and the chick chorioallantoic membrane vascular network. Elevated gene expression levels were found in the cardiac lobe compared to other lobes.
MICROVASCULAR RESEARCH
(2024)
