Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity

Novel HldE-K Inhibitors Leading to Attenuated Gram Negative Bacterial Virulence

(2013) Nicolas Desroy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression

(2013) R. J. Malott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intermolecular Binding between TIFA-FHA and TIFA-pT Mediates Tumor Necrosis Factor Alpha Stimulation and NF- B Activation

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Structural Insights into the Assembly of Large Oligomeric Signalosomes in the Toll-Like Receptor-Interleukin-1 Receptor Superfamily

(2012) R. Ferrao et al.   Science Signaling

A comprehensive platform for highly multiplexed mammalian functional genetic screens

(2011) Troy Ketela et al.   BMC GENOMICS

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

(2011) Leif E. Sander et al.   NATURE

STING is a direct innate immune sensor of cyclic di-GMP

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Essential Gene Profiles in Breast, Pancreatic, and Ovarian Cancer Cells

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Regulation of Adaptive Immunity by the Innate Immune System

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Approaching the Asymptote: 20 Years Later

(2009) Ruslan Medzhitov   IMMUNITY