Metal-organic frameworks as a very suitable reaction inductor for selective solvent-free multicomponent reaction: IRMOF-3 as a heterogeneous nanocatalyst for Kabachnik-Fields three-component reaction

IRMOF-3 is found to be an active, selective and stable solid catalyst for three-component, one-pot reaction of amines, aldehydes and dimethyl phosphite to form the corresponding alpha-aminophosphonates in high yields. The catalyst can be isolated from the reaction mixture and reused at least four times. (C) 2013 Elsevier Inc. All rights reserved.