Review
Biochemistry & Molecular Biology
Bruno Benedetti, Annika Weidenhammer, Maximilian Reisinger, Sebastien Couillard-Despres
Summary: Evidence suggests that cortical disinhibition can be either beneficial or detrimental in a context-dependent manner. Careful examination of clinical data and research using SCI animal models can help to better understand this mechanism and improve treatment outcomes through targeted pharmacological and rehabilitative interventions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Physiology
James L. Nuzzo, David S. Kennedy, Harrison T. Finn, Janet L. Taylor
Summary: The contemporary procedure for assessing voluntary activation of the knee extensor muscles with TMS is invalid, but a modified procedure may improve validity in select individuals meeting rigorous eligibility criteria.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Neurosciences
C. Barbi, G. Vernillo, M. Emadi Andani, G. Giuriato, F. G. Laginestra, A. Cavicchia, G. Fiorini Aloisi, C. Martignon, A. Pedrinolla, F. Schena, M. Venturelli
Summary: Researchers evaluated the accuracy of neuronavigated TMS (nTMS) and a standardized function-guided procedure for maintaining TMS coil position during neuromuscular evaluations. The study found that the spatial accuracy of TMS coil position did not affect corticospinal excitability and inhibition in knee extensors. Variability in MEP and SP responses was attributed to spontaneous fluctuations in corticospinal excitability and inhibition, unaffected by the stability of the stimulation point.
NEUROSCIENCE LETTERS
(2023)
Article
Neurosciences
Gianluca Vernillo, Chiara Barbi, John Temesi, Gaia Giuriato, Fabio Giuseppe Laginestra, Camilla Martignon, Federico Schena, Massimo Venturelli
Summary: This study aimed to assess the reliability of muscle relaxation induced by transcranial magnetic stimulation (TMS). The results showed that TMS can reliably measure changes in knee-extensor muscle relaxation rates, both in unfatigued and fatigued conditions.
NEUROSCIENCE LETTERS
(2022)
Review
Medicine, General & Internal
Leandro Ryuchi Iuamoto, Fabio Luis Kenji Ito, Thales Augusto Tome, Wu Tu Hsing, Alberto Meyer, Marta Imamura, Linamara Rizzo Battistella
Summary: This study contributes to a better understanding of the neurophysiological changes associated with knee osteoarthritis by observing neuroplasticity. These findings may aid in the early diagnosis of knee OA in the future. However, further research is still needed.
Article
Biochemistry & Molecular Biology
Kevin Pacheco-Barrios, Danielle Carolina Pimenta, Anne Victorio Pessotto, Felipe Fregni
Summary: The clinical correlates of transcranial magnetic stimulation (TMS) measures, such as resting motor threshold (MT), motor-evoked potential (MEP), short intracortical inhibition (SICI), and intracortical facilitation (ICF), in fibromyalgia syndrome (FMS) patients were investigated. It was found that SICI was associated with sleepiness, comorbidities, disease duration, and anxiety, while ICF showed a positive correlation with pain levels and a negative correlation with body mass index (BMI). These findings suggest that SICI and ICF metrics may serve as potential phenotyping biomarkers in FMS.
Article
Physiology
Olivier Girard, Martin Buchheit, Stuart Goodall, Sebastien Racinais
Summary: Exercise capacity decreases with increasing severity of hypoxia during exhaustive intermittent cycling, but neuromuscular fatigue characteristics do not differ significantly at task failure, and cardiovascular solicitation approaches maximal values in all conditions.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physiology
R. Buhmann, G. S. Trajano, G. K. Kerr, A. J. Shield
Summary: The study found that athletes with previous hamstring strain injuries exhibited increased levels of SICI in the biceps femoris muscle, which was associated with lower levels of muscle strength.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Geriatrics & Gerontology
Douglas N. Martini, Rosie Morris, Tara M. Madhyastha, Thomas J. Grabowski, John Oakley, Shu-Ching Hu, Cyrus P. Zabetian, Karen L. Edwards, Amie Hiller, Kathryn Chung, Katrina Ramsey, Jodi A. Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay B. Horak
Summary: The study found that impaired cortical sensorimotor inhibition was associated with slower gait in PD patients and increased gait variability and postural sway in OAs. However, no significant relationship was observed among mobility, cognition, and cortical sensorimotor inhibition.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Medicine, General & Internal
Linbo Peng, Kexin Wang, Yi Zeng, Yuangang Wu, Haibo Si, Bin Shen
Summary: This study found that postoperative NMES can improve quadriceps muscle strength, short to mid-term pain, and mid-term function following TKA based on analysis of 9 RCTs. However, some outcomes did not achieve statistically significant changes and minimal clinically important difference, requiring further confirmation of clinical benefits.
FRONTIERS IN MEDICINE
(2021)
Article
Clinical Neurology
Han Zhang, Yu Zhao, Yun Qu, Yunyun Huang, Zhu Chen, Hong Lan, Yi Peng, Hongying Ren
Summary: Cognitive impairment is a serious complication of traumatic brain injury (TBI) that impacts patients' quality of life. This study aims to investigate whether repetitive transcranial magnetic stimulation (rTMS) can improve memory and executive function in TBI patients. A randomized controlled trial will be conducted with 36 participants, and neuropsychological assessments will be performed. The preliminary results suggest positive effects of rTMS on memory and executive function in TBI patients.
FRONTIERS IN NEUROLOGY
(2022)
Review
Physiology
Alexandre Foure, Julien Gondin
Summary: This review focuses on the functional, structural, and cellular consequences of electrically evoked submaximal isometric contractions that can lead to severe and localized skeletal muscle damage, as well as discussing hypotheses related to the underlying physiological and mechanical processes involved.
EXERCISE AND SPORT SCIENCES REVIEWS
(2021)
Article
Neurosciences
Gianluca Vernillo, Arash Khassetarash, Guillaume Y. Millet, John Temesi
Summary: The study demonstrates that transcranial magnetic stimulation (TMS) can reliably assess muscle relaxation rates and is more sensitive and suitable than traditional femoral nerve stimulation for observing fatigue-induced changes in muscle relaxation in knee extensors.
EXPERIMENTAL BRAIN RESEARCH
(2021)
Article
Medicine, General & Internal
Seung Yeon Jeon, Jung Ho Choi, Sun Seong Kang, Yong-Hwi An, Hyun Joon Shim
Summary: Personalized neuromodulation, where treatment modalities are chosen based on the patient's responses in a pilot trial, is an advantageous strategy for treating tinnitus. The study found that the improvement in Tinnitus Handicap Inventory (THI) score after 10 sessions of each neuromodulation was significantly greater in the personalized group compared to the randomized group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Behavioral Sciences
Francesca Vitale, Ilaria Monti, Ivan Padron, Alessio Avenanti, Manuel de Vega
Summary: Applying negation in action contexts reduces motor system activation. The right inferior frontal gyrus (rIFG), a key area of the inhibitory control system, was found to contribute to the processing of negated action-sentences in the primary motor cortex (M1). Modulating rIFG suppressed the inhibitory effect of negation, resulting in equal motor excitability for negative and affirmative action sentences.
Article
Orthopedics
Kyle B. Kosik, Masafumi Terada, Ryan McCann, Abbey Thomas, Nathan Johnson, Phillip Gribble
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2020)
Article
Rehabilitation
Kyle B. Kosik, Nathan F. Johnson, Masafumi Terada, Abbey C. Thomas, Carl G. Mattacola, Phillip A. Gribble
PHYSICAL THERAPY IN SPORT
(2020)
Editorial Material
Sport Sciences
Abbey Thomas, Jeffrey B. Driban
INTERNATIONAL JOURNAL OF ATHLETIC THERAPY & TRAINING
(2020)
Article
Neurosciences
Katherine A. Collins, Michael J. Turner, Tricia Hubbard-Turner, Abbey C. Thomas
Article
Sport Sciences
Rachel R. Kleis, Janet E. Simon, Michael Turner, Luzita Vela, Abbey C. Thomas, Phillip A. Gribble
INTERNATIONAL JOURNAL OF ATHLETIC THERAPY & TRAINING
(2020)
Article
Neurosciences
Fatemeh Aghakeshizadeh, Amir Letafatkar, Abbey C. Thomas
Summary: The study found that males and females with Patellofemoral pain may benefit from completing a hip-knee strengthening training program with an external focus over an internal focus, leading to improvements in knee valgus and external rotator strength. Further research with larger sample sizes and longer follow-up periods could strengthen these findings.
Article
Engineering, Biomedical
Allison M. Knuckles, Danielle M. Torp, Tricia Hubbard-Turner, Luke Donovan, Abbey C. Thomas
Summary: This study assessed the impact of a multi-axis destabilisation device on plantar pressure and muscle activity in adults with chronic ankle instability during walking. The findings indicate that the destabilisation device effectively shifts plantar pressure while worn, but this effect is not retained after its removal. Further research is needed to determine the prolonged effects of the device beyond a single training session.
SPORTS BIOMECHANICS
(2022)
Article
Rehabilitation
Mohamad Ghaderi, Amir Letafatkar, Abbey C. Thomas, Sohrab Keyhani
Summary: The study investigated the effects of neuromuscular training with external focus of attention cueing on athletes post-ACL reconstruction. The experimental group showed improved biomechanics, knee proprioception, and patient-reported function after the intervention, while the control group showed no changes over the same time period.
BMC SPORTS SCIENCE MEDICINE AND REHABILITATION
(2021)
Article
Neurosciences
Bahram Sheikhi, Amir Letafatkar, Abbey C. Thomas
Summary: This study compared the front and back functional lines muscle activation in patients with ACLR and healthy participants during single leg vertical drop jump. Patients after ACLR may present with an alteration in BFL and FFL muscles activation during a drop jump task, potentially increasing the risk of ACL injury.
Article
Sport Sciences
Zohre Khosrokiani, Amir Letafatkar, Bahram Sheikhi, Abbey C. Thomas, Peyman Aghaie-ataabadi, Mohamad-Taghi Hedayati
Summary: The study suggests that side bridge and back bridge exercises are effective in improving gluteal muscle activation, while hand-knee exercise shows the least effectiveness in this aspect.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2022)
Article
Sport Sciences
Mohammad Fallah Mohammadi, Komeil Dashti Rostami, Sedighe Shabanzadeh, Sayed Esmaeil Hosseininejad, Salman Ghaffari, Abbey Thomas
Summary: This study found that core stability training can effectively reduce between-limb asymmetries in single-leg hopping and triple hopping tests among athletes post-ACL reconstruction. While there was no significant change in kinetics, functional performance was more symmetrical following core stability training.
RESEARCH IN SPORTS MEDICINE
(2022)
Article
Rehabilitation
Luke Donovan, Danielle M. Torp, Abbey C. Thomas
Summary: By observing the effects of auditory biofeedback training on center of pressure (COP) location during gait, it was found that patients with chronic ankle instability can significantly shift their COP location medially after approximately 15 minutes of training and require 4 sessions to retain the adapted gait pattern.
PHYSICAL THERAPY IN SPORT
(2023)
Article
Multidisciplinary Sciences
Mahsa Emamvirdi, Mahdi Hosseinzadeh, Amir Letafatkar, Abbey C. Thomas, Thomas Dos'Santos, Nicola Smania, Giacomo Rossettini
Summary: This study found that female basketball athletes with chronic ankle instability (CAI) and patellofemoral pain (PFP) exhibit asymmetries in ankle dorsiflexion range of motion and dynamic knee valgus kinematics, which are associated with the Lateral Step-Down Test (LSD). These findings highlight the importance of evaluating and reducing limb asymmetries in these populations.
SCIENTIFIC REPORTS
(2023)
Article
Sport Sciences
Danielle M. Torp, Abbey C. Thomas, Tricia Hubbard-Turner, Luke Donovan
Summary: The study showed that visual and auditory biofeedback can improve balance strategies and promote proper biomechanics in individuals with chronic ankle instability.
JOURNAL OF ATHLETIC TRAINING
(2021)
Article
Rehabilitation
Mohammad H. Izadi Farhadi, Foad Seidi, Hooman Minoonejad, Abbey C. Thomas
JOURNAL OF SPORT REHABILITATION
(2020)