Article
Chemistry, Analytical
Yanming Xia, Chao Song, Yingchao Meng, Peng Xue, Andrew J. deMello, Quan Gao, Stavros Stavrakis, Shenglin Ma, Xiaobao Cao
Summary: Centrifugal microfluidic platforms integrate and perform complex biological and chemical processes within disc-like substrates and valving using centrifugal forces and the Coriolis effect. Researchers have developed and tested an addressable electrowetting centrifugal (EWC) valve, which can be triggered to open by altering its wettability through an external electric field. The valve demonstrates good performance in multiple operations on different fluid samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Iman Frozanpoor, Michael D. Cooke, Vibin Ambukan, Andrew J. Gallant, Claudio Balocco
Summary: This work introduces a new technology for actuating droplets without the need for high voltages or active control systems. Through experiments, it has been demonstrated that this technology is feasible on various platforms. The technology not only has potential applications in microfluidics, but also in industries such as automotive for self-cleaning platforms.
Article
Nanoscience & Nanotechnology
Ali Reza Bahari, Mobin Abdar Esfahani, Mojtaba Taghipoor
Summary: Transparent electrowetting is a branch of EWOD devices that use transparent electrodes for optical applications. This paper introduces a transparent EWOD with permanent liquid electrodes. Liquid electrodes were used instead of conventional solid-state ones. The concept of Liquid Electrode EWOD (LEWOD) is successfully implemented on both rigid and flexible substrates. Results show promising performance similar to PCBs, indicating potential future applications of liquid electrodes in EWOD systems.
MICROFLUIDICS AND NANOFLUIDICS
(2023)
Article
Materials Science, Multidisciplinary
Dorina T. Papanastasiou, Abderrahime Sekkat, Viet Huong Nguyen, Carmen Jimenez, David Munoz-Rojas, Franz Bruckert, Daniel Bellet
Summary: This paper introduces a transparent heater based on silver nanowire networks, protected with a transparent zinc oxide film, for temperature control in biological experiments under transparent microscopic observation. The experimental results demonstrate that the nanocomposites allow rapid and reproducible heating under low applied voltage, and achieve selective heating in different zones of microchannels or adjacent microchannels at different temperatures.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Chemistry, Analytical
Nafisat Gyimah, Ott Scheler, Toomas Rang, Tamas Pardy
Summary: 3D printing technology shows potential in microfluidic chip fabrication and is mature enough for use in research labs. However, challenges still need to be overcome.
Article
Physics, Applied
Rui Zhou, Xiaoting Fang, Qi Cheng, Lei Zhuang, Hui Li, Biao Tang, Guofu Zhou
Summary: This study demonstrates that fluid motion control and device performance in optical electrowetting devices can be improved by introducing an inkjet-printed polytitanosiloxane layer. Experimentally, different structural parameters of the IPP layer were found to affect both microscopic and macroscopic performances of the device.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Chemistry, Multidisciplinary
Hui Liu, Guangyi Shi, Rashid Khan, Shenglong Chu, Zongming Huang, Tongfei Shi, Haiding Sun, Yaping Li, Hongmin Zhou, Peng Xiao, Tao Chen, Zhengguo Xiao
Summary: A robust inkjet printing strategy is developed to fabricate large-area flexible perovskite light-emitting diodes (PeLEDs). By using a wetting interlayer and solvent engineering, uniform perovskite films are obtained on flexible substrates, resulting in efficient PeLEDs with a peak external quantum efficiency of 14.3%. The red, green, and sky-blue large-area (28 cm2) flexible PeLEDs also exhibit uniform emission.
ADVANCED MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Hyunji Shim, Siwon Hwang, Eunjeong Byun, Minyoung Choi, Bongjun Kim, Seunghyun Song
Summary: This study develops a method to embed patterned plasmonic metal nanoparticles in silicone elastomer by inkjet printing metal ion solution. The capability of patterning is demonstrated and a photothermal microfluidic pump is fabricated, showing the potential utility of the inkjet patterned metal nanoparticles in silicone elastomer.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Biochemical Research Methods
He Wang, Liguo Chen
Summary: Flexible printed electronic technology enables low-cost fabrication of digital microfluidic chips, with inkjet printing on flexible substrates being a cost-effective method. The surface quality, conductivity, and resolution of silver lines on two types of flexible DMF chips were comprehensively analyzed. Droplet motion between closed and open regions was studied, and experiments showed that the performance of droplets can be comparable to traditional technology.
IEEE TRANSACTIONS ON NANOBIOSCIENCE
(2022)
Article
Chemistry, Analytical
Shiyu Chen, Zhidong He, Suhwan Choi, Igor V. Novosselov
Summary: This study investigates the use of inkjet printing for fabricating digital microfluidics (DMF) devices and compares different dielectric coatings. The results show that devices utilizing Kapton as the coating are more robust, even functioning normally at actuation voltages up to 100 V.
Article
Materials Science, Multidisciplinary
Anatolii Makhinia, Pooya Azizian, Valerio Beni, Jasmina Casals-Terre, Joan M. Cabot, Peter Andersson Ersman
Summary: Microfluidic surface chemistry allows for control of capillary-driven flow without bulky external instrumentation. A novel nonhomogeneous coating is used to define regions with different wetting properties on microchannel walls, leading to different capillary pressures and automatic flow control. This method employs inkjet printing to deposit hydrophilic coatings on the surfaces of 3D-printed microfluidic devices, enabling capillary flow control in 3D-printed microfluidics for the first time. The method is further utilized to create stop and delay valves and integrated with organic electrochemical transistors for sensing applications.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Multidisciplinary
Jingjie Du, Botao Zhang, Meng Jiang, Qihao Zhang, Keyi Zhang, Yan Liu, Lianjun Wang, Wan Jiang
Summary: The development of flexible thermoelectric devices presents exciting opportunities for wearable applications in various fields. However, scaling up nanotechnology-enabled thermoelectric materials and reducing manufacturing costs remain challenging. This study introduces an inkjet printing method to fabricate high-performance flexible thermoelectric devices. The use of a templated-directed chemical transformation process allows the synthesis of metal chalcogenide nanowires, which are turned into printable inks. The resulting inkjet-printed flexible films and devices show significantly improved performance compared to state-of-the-art inkjet-printed thermoelectrics, indicating the potential of this printing platform for scalable manufacturing of next-generation flexible thermoelectric devices.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Pavel Yazhgur, Nicolas Muller, Frank Scheffold
Summary: This article demonstrates the use of photonic ball dispersions as inkjet printing inks, increasing color purity and suppressing multiple scattering.
Article
Chemistry, Analytical
Zhaoxuan Fan, Yucheng Sun, Jin-Ming Lin
Summary: This study developed a method for molecular detection using a self-assembled inkjet printer. By generating discrete droplets, the inkjet printer enabled low-cost and practical droplet digital loop-mediated isothermal amplification. The results showed that this method successfully quantified HPV16.
Article
Nanoscience & Nanotechnology
Niclas Weigel, Max J. Maennel, Julian Thiele
Summary: The study focuses on developing resins for high-resolution additive manufacturing of flexible micromaterials through projection micro-stereolithography (P mu SL). The best-candidate resin allows for 3D-printing transparent microchannels with a minimum cross section and exhibits proper solvent resistance. The mechanical properties are suitable for 3D-printing microfluidic devices with integrated functional units, expanding the library of functional resins for P mu SL printing towards flexible materials with micrometer resolution.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Analytical
T. C. Hinkley, S. Garing, S. Singh, A-L M. Le Ny, K. P. Nichols, J. E. Peters, J. N. Talbert, S. R. Nugen
Article
Multidisciplinary Sciences
Troy C. Hinkley, Sangita Singh, Spencer Garing, Anne-Laure M. Le Ny, Kevin P. Nichols, Joseph E. Peters, Joey N. Talbert, Sam R. Nugen
SCIENTIFIC REPORTS
(2018)
Article
Chemistry, Analytical
Troy C. Hinkley, Spencer Garing, Paras Jain, John Williford, Anne-Laure M. Le Ny, Kevin P. Nichols, Joseph E. Peters, Joey N. Talbert, Sam R. Nugen
Review
Biochemical Research Methods
Caitlin M. Carmody, Julie M. Goddard, Sam R. Nugen
Summary: Bacteriophages are versatile viruses with potential applications in agriculture and public health. Their capsids can be modified genetically or chemically to enhance specificity and stability for various functions.
BIOCONJUGATE CHEMISTRY
(2021)
Article
Microbiology
Anqi Chen, Danhui Wang, Sam R. Nugen, Juhong Chen
Summary: Utilizing an enzyme-based fluorescent assay, the study demonstrated a sensitive method for detecting the presence of E. coli in food samples, providing a straightforward approach to detect potential biological contamination. The engineered phages showed a detection limit of 10 CFU/mL and could be applied to detect E. coli strains from environmental samples.
Article
Nanoscience & Nanotechnology
Kathryn A. Hufziger, Emma L. Farquharson, Brenda G. Werner, Qingmin Chen, Julie M. Goddard, Sam R. Nugen
Summary: The current techniques for bacteriophage immobilization onto magnetic particles are limited in cost-effectiveness and specificity. This study presents a plasmid-based technique that incorporates a silica-binding protein into the phage capsid, enabling targeted binding to silica without modifying the phage genome. By improving immobilization density, this technique offers a step toward reducing cost and increasing specificity in phage immobilization methods.
ACS APPLIED BIO MATERIALS
(2022)
Article
Microbiology
Emma L. Farquharson, Sam R. Nugen
Summary: The complete genome sequence and annotation of bacteriophage Ac3 is presented in this study. The host range of Ac3 was evaluated using spot tests and plaque assays, revealing its ability to adsorb to 59.7% of Escherichia coli strains and replicate within 37.5% of the strains. This research provides a solid starting point for future investigations.
PHAGE-THERAPY APPLICATIONS AND RESEARCH
(2022)
Article
Microbiology
Caitlin M. Carmody, Emma L. Farquharson, Sam R. Nugen
Summary: This study presents the complete genome sequence and host range determination of phage SV76, highlighting its requirement for specific receptor binding proteins. SV76 is closely related to T2 and exhibits similar host ranges within ECOR, laying a foundation for future studies on T4-like phages and their biotechnological applications.
PHAGE-THERAPY APPLICATIONS AND RESEARCH
(2022)
Article
Education, Scientific Disciplines
Alexandra J. Macbeth, Hannah S. Zurier, Erin Atkins, Sam R. Nugen, Julie M. Goddard
Summary: Connecting the public to STEM concepts is crucial for technological advancement and inspiring future scientists, impacting both the communicator and the audience's understanding of scientific topics. Increasing public awareness about scientific issues through STEM engagement can lead to informed policy and consumer choices, particularly in fields such as food science where new technologies face initial resistance.
JOURNAL OF FOOD SCIENCE EDUCATION
(2021)
Article
Nanoscience & Nanotechnology
Hannah S. Zurier, Michelle M. Duong, Julie M. Goddard, Sam R. Nugen
ACS APPLIED BIO MATERIALS
(2020)
Article
Chemistry, Analytical
Michelle M. Duong, Caitlin M. Carmody, Sam R. Nugen
Article
Cell Biology
Elsi M. Pulkkinen, Troy C. Hinkley, Sam R. Nugen
INTEGRATIVE BIOLOGY
(2019)
Article
Chemistry, Analytical
Danhui Wang, Troy Hinkley, Juhong Chen, Joey N. Talbert, Sam R. Nugen
Article
Biotechnology & Applied Microbiology
Sangita Singh, Troy Hinkley, Sam R. Nugen, Joey N. Talbert
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2018)
Meeting Abstract
Chemistry, Multidisciplinary
Troy Hinkley, Sam Nugen
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2017)