期刊
MICROFLUIDICS AND NANOFLUIDICS
卷 11, 期 1, 页码 87-92出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s10404-011-0776-7
关键词
Nano-microfluidics; Droplet; Attoliter; Monodisperse; Capillary focusing
资金
- Dutch Ministry of Economic Affairs
We demonstrate a robust method to produce monodisperse femtoliter to attoliter droplets by using a nano-microfluidic device. Two immiscible liquids are forced through a nanochannel where a steady nanoscopic liquid filament forms, thinning close to the nanochannel exit to a microchannel due to the capillary focusing. When the nanoscopic filament enters the microchannel, monodisperse droplets are formed by capillary instability. In a certain range of physical parameters and geometrical configurations, the droplet size is only determined by the nanochannel height and independent of liquid flow rates and ratios, surfactants, and continuous phase viscosity. By using nanochannels with a height of 100-900 nm, 0.4-3.5 mu m diameter droplets (volume down to 30 aL) have been produced. The generated droplets are stable for at least weeks.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据