Bone Fracture Enhances Trauma Brain Injury

DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury

(2015) A. Liesz et al.   JOURNAL OF NEUROSCIENCE

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Clinical evidence of inflammation driving secondary brain injury

(2015) Holly E. Hinson et al.   Journal of Trauma and Acute Care Surgery

Activation of NF-κB Mediates Astrocyte Swelling and Brain Edema in Traumatic Brain Injury

(2014) Arumugam R. Jayakumar et al.   JOURNAL OF NEUROTRAUMA

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(2014) Fleur Schaper et al.   MOLECULAR MEDICINE

Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1–RAGE interaction

(2014) Yu Okuma et al.   NEUROPHARMACOLOGY

Taurine improves functional and histological outcomes and reduces inflammation in traumatic brain injury

(2014) Y. Su et al.   NEUROSCIENCE

The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation

(2014) D. J. Weber et al.   Science Translational Medicine

Immune Activation Promotes Depression 1 Month After Diffuse Brain Injury: A Role for Primed Microglia

(2013) Ashley M. Fenn et al.   BIOLOGICAL PSYCHIATRY

Intracellular Hmgb1 Inhibits Inflammatory Nucleosome Release and Limits Acute Pancreatitis in Mice

(2013) Rui Kang et al.   GASTROENTEROLOGY

Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection

(2013) H. Yanai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice

(2013) Benjamin L. Woolbright et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Anti-high mobility group box-1 antibody therapy for traumatic brain injury

(2012) Yu Okuma et al.   ANNALS OF NEUROLOGY

Cerebrospinal Fluid Levels of High-Mobility Group Box 1 and Cytochrome C Predict Outcome after Pediatric Traumatic Brain Injury

(2012) Alicia K. Au et al.   JOURNAL OF NEUROTRAUMA

Expression of HMGB1 and RAGE in rat and human brains after traumatic brain injury

(2012) Tie-Lei Gao et al.   Journal of Trauma and Acute Care Surgery

Systemic Inflammatory Effects of Traumatic Brain Injury, Femur Fracture, and Shock: An Experimental Murine Polytrauma Model

(2012) C. Probst et al.   MEDIATORS OF INFLAMMATION

Severe Stroke Induces Long-Lasting Alterations of High-Mobility Group Box 1

(2012) Juliane Schulze et al.   STROKE

Coexpression of Angiopoietin-1 with VEGF Increases the Structural Integrity of the Blood–Brain Barrier and Reduces Atrophy Volume

(2011) Fanxia Shen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Beneficial Effects of Ethyl Pyruvate through Inhibiting High-Mobility Group Box 1 Expression and TLR4/NF-κB Pathway after Traumatic Brain Injury in the Rat

(2011) Xingfen Su et al.   MEDIATORS OF INFLAMMATION

Role of interleukin-1β in postoperative cognitive dysfunction

(2010) Mario Cibelli et al.   ANNALS OF NEUROLOGY

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

(2010) Jenna M. Ziebell et al.   Neurotherapeutics

Role of microglia in neurotrauma

(2010) David J. Loane et al.   Neurotherapeutics

HMGB1 IS MARKEDLY ELEVATED WITHIN 6 HOURS OF MECHANICAL TRAUMA IN HUMANS

(2009) Erik D. Peltz et al.   SHOCK

IL-6 predicts organ dysfunction and mortality in patients with multiple injuries

(2009) Michael Frink et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Traumatic brain injury: Can the consequences be stopped?

(2008) E. Park et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats

(2008) Akira Utagawa et al.   EXPERIMENTAL NEUROLOGY

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA