Cytoprotective Signaling and Gene Expression in Endothelial Cells and Macrophages-Lessons for Atherosclerosis

Plaque neovascularization: defense mechanisms, betrayal, or a war in progress

(2012) Pedro R. Moreno et al.   Annals of the New York Academy of Sciences

The Transcription Factor Erg Controls Endothelial Cell Quiescence by Repressing Activity of Nuclear Factor (NF)-κB p65

(2012) Nicola H. Dryden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ETS-related Gene (ERG) Controls Endothelial Cell Permeability via Transcriptional Regulation of the Claudin 5 (CLDN5) Gene

(2012) Lei Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme Induces Heme Oxygenase 1 via Nrf2

(2011) Joseph J. Boyle et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis

(2011) G. M. Birdsey et al.   BLOOD

Intravital Microscopy on Atherosclerosis in Apolipoprotein E–Deficient Mice Establishes Microvessels as Major Entry Pathways for Leukocytes to Advanced Lesions

(2011) Einar E. Eriksson   CIRCULATION

Dexamethasone Arterializes Venous Endothelial Cells by Inducing Mitogen-Activated Protein Kinase Phosphatase-1

(2011) Mustafa Zakkar et al.   CIRCULATION

Disturbed Blood Flow Induces RelA Expression via c-Jun N-Terminal Kinase 1

(2011) Simon Cuhlmann et al.   CIRCULATION RESEARCH

Activating Transcription Factor 1 Directs Mhem Atheroprotective Macrophages Through Coordinated Iron Handling and Foam Cell Protection

(2011) Joseph J. Boyle et al.   CIRCULATION RESEARCH

Intraplaque haemorrhages as the trigger of plaque vulnerability

(2011) J.-B. Michel et al.   EUROPEAN HEART JOURNAL

Hemoglobin Directs Macrophage Differentiation and Prevents Foam Cell Formation in Human Atherosclerotic Plaques

(2011) Aloke V. Finn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

c-Jun N-Terminal Kinase Primes Endothelial Cells at Atheroprone Sites for Apoptosis

(2010) Hera Chaudhury et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Transcription Factor Erg Inhibits Vascular Inflammation by Repressing NF-κB Activation and Proinflammatory Gene Expression in Endothelial Cells

(2010) Andrea Sperone et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ERG is required for the differentiation of embryonic stem cells along the endothelial lineage

(2010) Vesna Nikolova-Krstevski et al.   BMC DEVELOPMENTAL BIOLOGY

The Alternative Pathway Is Critical for Pathogenic Complement Activation in Endotoxin- and Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2010) Talat H. Malik et al.   CIRCULATION

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

Minireview: Global Regulation and Dynamics of Ribonucleic Acid

(2010) Jack D. Keene   ENDOCRINOLOGY

Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium

(2010) Shahir S. Hamdulay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Coronary Intraplaque Hemorrhage Evokes a Novel Atheroprotective Macrophage Phenotype

(2009) Joseph J. Boyle et al.   AMERICAN JOURNAL OF PATHOLOGY

Decay-Accelerating Factor Suppresses Complement C3 Activation and Retards Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

(2009) Viola W.Y. Leung et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State

(2009) Mustafa Zakkar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions

(2009) Marcienne M. WRIGHT et al.   BIOCHEMICAL JOURNAL

PPARδ and PGC1α act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress

(2009) Faisal Ali et al.   CARDIOVASCULAR RESEARCH

Macrophage-Specific Expression of Mannose-Binding Lectin Controls Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

(2009) Robert A. Matthijsen et al.   CIRCULATION

Heme Oxygenase 1 Determines Atherosclerotic Lesion Progression Into a Vulnerable Plaque

(2009) Caroline Cheng et al.   CIRCULATION

Antiinflammatory Effects of the ETS Factor ERG in Endothelial Cells Are Mediated Through Transcriptional Repression of the Interleukin-8 Gene

(2009) Lei Yuan et al.   CIRCULATION RESEARCH

Induction of the Cytoprotective Enzyme Heme Oxygenase-1 by Statins Is Enhanced in Vascular Endothelium Exposed to Laminar Shear Stress and Impaired by Disturbed Flow

(2009) Faisal Ali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme Oxygenase-1 and the Vascular Bed: From Molecular Mechanisms to Therapeutic Opportunities

(2008) Agnieszka Loboda et al.   ANTIOXIDANTS & REDOX SIGNALING

PPARs and the Cardiovascular System

(2008) Milton Hamblin et al.   ANTIOXIDANTS & REDOX SIGNALING

Brief Report: Accelerated Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice Lacking the Membrane-Bound Complement Regulator CD59

(2008) Sheng Yun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin

(2008) A. R. Kinderlerer et al.   BLOOD

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin

(2008) G. M. Birdsey et al.   BLOOD

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Atheroprotective Signaling Mechanisms Activated by Steady Laminar Flow in Endothelial Cells

(2008) Bradford C. Berk   CIRCULATION

Peroxisome Proliferator-Activated Receptor β/δ Goes Vascular

(2008) David Bishop-Bailey   CIRCULATION RESEARCH

Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis

(2008) Mustafa Zakkar et al.   CIRCULATION RESEARCH

The role of complement in atherosclerosis

(2008) Dorian O Haskard et al.   CURRENT OPINION IN LIPIDOLOGY

KLF2-dependent, Shear Stress-induced Expression of CD59

(2008) Anne R. Kinderlerer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

(2008) Peter F Davies   Nature clinical practice. Cardiovascular medicine