Article
Chemistry, Multidisciplinary
Shanyu Zhang, Zhenyuan Cao, Pingping Fan, Yuqin Wang, Wendong Jia, Liying Wang, Kefan Wang, Yao Liu, Xiaoyu Du, Chengzhen Hu, Panke Zhang, Hong-Yuan Chen, Shuo Huang
Summary: Saccharides play critical roles in cellular activities, and the identification of their complex and similar structures presents a technical challenge. Researchers have developed a nanopore sensing strategy that can identify saccharides based on minor structural differences. They also trained a machine learning algorithm for automatic event classification and achieved a high accuracy score.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Analytical
Kangkang Wang, Tingting Yao, Jiayu Xue, Yanqiu Guo, Xiaowei Xu
Summary: Hydrogen peroxide (H2O2), an important reactive oxygen species (ROS), is closely related to various pathological and physiological processes in living organisms. Excessive H2O2 can lead to diseases such as cancer, diabetes, and cardiovascular diseases, necessitating the detection of H2O2 in living cells. This study designed a new fluorescent probe that effectively detects H2O2 with high selectivity and measures cellular ROS levels, providing a potential monitoring tool for various diseases caused by H2O2 excess.
Review
Chemistry, Multidisciplinary
George T. Williams, Jonathan L. Kedge, John S. Fossey
Summary: This article discusses the importance of carbohydrate sensing in biomedical applications, outlining efforts to understand the complexity of carbohydrates to develop more selective sensors.
Article
Chemistry, Analytical
Yong Chang, Gang Liu, Shuang Li, Lin Liu, Qijun Song
Summary: In this study, an antibody and enzyme-free electrochemical method was proposed for the accurate and sensitive determination of recombinant glycoproteins. The method showed a wide linear detection range and a low detection limit, making it promising for applications in biopharmaceutical research, anti-doping analysis, and clinical diagnosis.
ANALYTICA CHIMICA ACTA
(2023)
Article
Environmental Sciences
Zhiyang Lin, Linhan Li, Kaige Song, Bin Yang, Guoqing Zhou, Gengrong Zhang, Jiang Teng, Erlong Wang, Xiaoqiang Liu, Fei Ling, Gaoxue Wang, Tianqiang Liu
Summary: Viruses pose a significant threat to humans when present in contaminated waters, especially for vulnerable populations. In this study, bench-scale experiments were conducted to evaluate the removal of a model virus (SVCV) in water using boronic acid-modified bacterial cellulose microspheres as adsorbents. The results showed that SVCV was effectively removed with a 3-log reduction in virus concentration within 3 hours. This research provides substantial evidence that bacterial cellulose-based materials have the potential for virus removal from water, which is of great importance.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Xue Tian, Lloyd C. Murfin, Luling Wu, Simon E. Lewis, Tony D. James
Summary: Small-molecule based fluorescent probes play an increasingly important role in detecting and imaging biological signaling molecules due to their simplicity, high selectivity, and real-time analysis capabilities. Various sensing mechanisms, including FRET, ICT, PeT, ESIPT, AIE, as well as dual/triple sensing mechanisms, are highlighted, but challenges remain. Future development should focus on improving small-molecule fluorescent probes for biosensing applications.
Article
Chemistry, Organic
Min Sik Eom, Byoung Yong Park, Seungyoon Kang, Min Su Han
Summary: A salicylimine-based fluorophore, Di-OH, was developed that selectively responded to boric acid over boronic acid. It was further applied for screening the conversion rate of a chemical reaction.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Biochemical Research Methods
Akira Matsumoto, Shigehito Osawa, Takahiro Arai, Yukie Maejima, Hidenori Otsuka, Yuji Miyahara
Summary: The study demonstrates a label-free, enzymatic-free, potentiometric determination of fetuin using boronic acid-based SA-recognition chemistry on a gold electrode. The method shows a micro M-order sensitivity comparable to blood-collected specimens, suggesting potential for developing a cost-effective hemodiagnostic technology with ease of downsizing and mass production.
BIOCONJUGATE CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Peng Yang, Xin Zhou, Jianhua Zhang, Jian Zhong, Fang Zhu, Xianhu Liu, Zhipeng Gu, Yiwen Li
Summary: Fluorescent polymer dots (PDs) were successfully prepared from natural polyphenols via one-pot co-polymerization under mild conditions without the use of organic solvents or harsh chemicals. The resulting PDs exhibited good photostability and biocompatibility, as well as high selectivity towards copper ions. This green and facile strategy opens up new possibilities for the design and preparation of natural molecule-based PDs for biomedical and environmental applications.
Article
Chemistry, Medicinal
Dongxue Zhan, Zhancun Bian, Haizhen Li, Ran Wang, Guiqian Fang, Qingqiang Yao, Zhongyu Wu
Summary: This study reports a novel water-soluble boronic acid sensor with double recognition sites. The sensor can sensitively recognize gallic acid and has no recognition ability towards other analytes. It has a fast response time and a high binding constant, making it a potential tool for the detection of gallic acid in actual samples.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Analytical
Xiang Xiong, Wenya Dang, Ruxin Luo, Ying Long, Chunyi Tong, Liqin Yuan, Bin Liu
Summary: This study developed a versatile nanoprobe based on rGO and DNA probe for simultaneous visualization of miR451a and miR-214-3p in living cells, showing excellent selectivity and sensitivity. In vitro experiments demonstrated good linearity of detection signals for miR-451a and miR-214-3p, and successful dual-color imaging in human breast cancer cells was achieved using the nanoprobe.
Article
Chemistry, Multidisciplinary
Andrew J. Carrod, Francesco Graglia, Louise Male, Cecile Le Duff, Peter Simpson, Mohamed Elsherif, Zubair Ahmed, Haider Butt, Guang-Xi Xu, Kenneth Kam-Wing Lo, Paolo Bertoncello, Zoe Pikramenou
Summary: Dual detection systems are beneficial for rapid and accurate data collection in sensing systems and in vitro testing. The newly introduced Ir-III complex with a boronic acid receptor site attached to a 2-phenylpyridine ligand serves as an ideal probe for sensitive detection of monosaccharide binding, showing potential for integration into devices.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Shuai Chen, Xuewei Zhang, Yongliang Yu, Jianhua Wang
Summary: A novel fluorescence sensor array was developed for rapid and accurate discrimination of glycoproteins and cancer cells, with simple operation. The study demonstrated successful discrimination of various glycoproteins and cell types at low concentrations, including potential application in cancer cell identification.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Applied
Xiaoli Qian, Hui Yu, Wenchao Zhu, Xufeng Yao, Wangwang Liu, Shikui Yang, Fangyuan Zhou, Yi Liu
Summary: The new fluorescence HOCl probe NFL-S combines high sensitivity and selectivity, successfully detecting endogenous HOCl and functioning in oxidative stress imaging.
Article
Chemistry, Multidisciplinary
Ines J. Marques, Pedro D. Vaz, Ana V. Girao, Mariela M. Nolasco, Carla D. Nunes
Summary: Silica-coated iron oxide and silica nanoparticles were prepared and derivatized with a europium complex to yield magneto-fluorescent and fluorescent nanomaterials. The fluorescence was enhanced by the anchored europium complex and maintained in cellular medium. These nanomaterials have potential applications as biosensors and in imaging.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Sarka Bidmanova, Mark-Steven Steiner, Martin Stepen, Kamila Vymazalova, Michael A. Gruber, Axel Duerkop, Jiri Damborsky, Zbynek Prokop, Otto S. Wolfbeis
ANALYTICAL CHEMISTRY
(2016)
Article
Chemistry, Multidisciplinary
Xinhong Song, Yiying Chen, Mingcong Rong, Zhaoxiong Xie, Tingting Zhao, Yiru Wang, Xi Chen, Otto S. Wolfbeis
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2016)
Article
Chemistry, Multidisciplinary
Lei Zhao, Xiaoqian Ge, Guihua Yan, Xiao Wang, Pengfei Hu, Liyi Shi, Otto S. Wolfbeis, Hongjie Zhang, Lining Sun
Article
Chemistry, Analytical
Verena Muhr, Markus Buchner, Thomas Hirsch, Dragana J. Jovanovic, Slobodan D. Dolic, Miroslav D. Dramicanin, Otto S. Wolfbeis
SENSORS AND ACTUATORS B-CHEMICAL
(2017)
Article
Chemistry, Multidisciplinary
Christoph Fenzl, Pranati Nayak, Thomas Hirsch, Otto S. Wolfbeis, Husam N. Alshareef, Antje J. Baeumner
Article
Nanoscience & Nanotechnology
Fangyuan Lin, Feiming Li, Zhiwei Lai, Zhixiong Cai, Yiru Wang, Otto S. Wolfbeis, Xi Chen
ACS APPLIED MATERIALS & INTERFACES
(2018)
Expression of Concern
Chemistry, Analytical
Otto S. Wolfbeis
Article
Chemistry, Multidisciplinary
Yongjiu Lei, Wenii Zhao, Yizhou Zhang, Qiu Jiang, Jr-Hou He, Antjej Baeumner, Otto S. Wolfbeis, Zhong Lin Wang, Khaled N. Salama, Husam N. Aishareef
Review
Chemistry, Analytical
Xu-dong Wang, Otto S. Wolfbeis
ANALYTICAL CHEMISTRY
(2020)
Review
Chemistry, Analytical
Veerappan Mani, Tutku Beduk, Walaa Khushaim, Ayse Elcin Ceylan, Suna Timur, Otto S. Wolfbeis, Khaled Nabil Salama
Summary: Salivary markers analysis has become a promising non-invasive approach for easy, safe, and pain-free monitoring, with the potential to impact clinical diagnosis and management. Advancements in sensing technology, novel materials, innovative fabrication technologies, and sampling accuracy have established saliva as a routine fluid for analysis, with applications in diagnosing various diseases.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Analytical
Otto S. Wolfbeis
Summary: Chameleon labels have the unique property of changing color and fluorescence when binding to amino groups of biomolecules, making them useful for labeling proteins and oligonucleotides with specificity. The review is divided into sections that cover introduction, classification, and reaction patterns of different types of fluorescent labels.
METHODS AND APPLICATIONS IN FLUORESCENCE
(2021)
Review
Chemistry, Multidisciplinary
Andreas Steinegger, Otto S. Wolfbeis, Sergey M. Borisov
Review
Biophysics
Abdellatif Ait Lahcen, Sakandar Rauf, Tutku Beduk, Ceren Durmus, Abdulrahman Aljedaibi, Suna Timur, Husam N. Alshareef, Aziz Amine, Otto S. Wolfbeis, Khaled N. Salama
BIOSENSORS & BIOELECTRONICS
(2020)
Proceedings Paper
Engineering, Electrical & Electronic
Rafiq Ahmad, Sandeep G. Surya, Josk Batista Sales, Hend Mkaouar, Sebastian Yuri Cavalcanti Catunda, Diomadson Rodrigues Belfort, Yongjiu Lei, Zhong Lin Wang, Antje Baeumner, Otto S. Wolfbeis, Husam N. Alshareef, Khaled N. Salama
Article
Materials Science, Multidisciplinary
Rafiq Ahmad, Otto S. Wolfbeis, Yoon-Bong Hahn, Husam N. Alshareef, Luisa Torsi, Khaled N. Salama
MATERIALS TODAY COMMUNICATIONS
(2018)
