Article
Electrochemistry
Haruki Katori, Atsushi Kitada, Kazuhiro Fukami, Kuniaki Murase
Summary: In this study, the initial behavior of trivalent chromium electrodeposition was investigated using chloride-based hydrate-melts. Proton reduction and chromium hydroxide precipitation were observed in the very early stage of electrolysis. The reduction of chromium required a few seconds of induction time and was associated with proton depletion near the cathode. The use of hydrate-melts resulted in the high current efficiencies of chromium electrodeposits due to the suppression of hydrogen evolution.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Multidisciplinary Sciences
Bright O. Okonkwo, Chaewon Jeong, Hyeon Bae Lee, Changheui Jang, Ehsan Rahimi, Ali Davoodi
Summary: In this study, a trivalent chromium coating electrodeposited on 304L stainless steel was developed and optimized. The results showed that the grain sizes of the coatings decreased and the cracking density reduced with an increase in bath temperature. The mechanical and electrochemical tests demonstrated that the coatings deposited at a bath temperature of 80 degrees C had the best performance in terms of adhesion, wear resistance, and pitting resistance.
Article
Chemistry, Physical
Zhichun Cui, Yuezhong Di, Jianping Peng, Yaowu Wang, Naixiang Feng
Summary: The current research focuses on the mechanism of PEG in the preparation of magnesium hydroxide by electrolysis. PEG plays a crucial role in adjusting the growth mode and morphology of Mg(OH)2 crystals. When the PEG content reaches 0.4 g/L, the product has uniform particle size, reduces polarization of the electrode plate, and improves the economic benefit. However, low or high PEG content may have a negative impact on the product and economic benefits of the electrolytic reaction.
Review
Chemistry, Analytical
Xiaoyu Zhao, Haoqiang Gao, Yongdan Hou, Lemuel Gbologah, Xiangdong Zeng, Yanfei Wang
Summary: Quartz Crystal Microbalance (QCM) is a scientific instrument based on the piezoelectric effect of quartz crystals, offering versatile, reliable, and sensitive in-situ sensing capabilities for small quantity variations. QCM and Electrochemical-QCM (EQCM) techniques have been used for precise analysis and control of crystallization and electrodeposition processes, providing implicit information through complex frequency changes. The future applications of QCM in this field show great potential and promise.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Shuo Jin, Duhan Zhang, Arpita Sharma, Qing Zhao, Yiqi Shao, Pengyu Chen, Jingxu Zheng, Jiefu Yin, Yue Deng, Prayag Biswal, Lynden A. Archer
Summary: A method of crystal growth stabilization using polymer-salt complexes has been proposed to reshape the deposition of crystalline metals, allowing for exceptional morphological control and unprecedented cycle life in rechargeable batteries utilizing zinc as an anode material. Preliminary studies have demonstrated the practical benefits of this approach in Zn-I2 full battery cells.
Article
Materials Science, Coatings & Films
Ying Wang, Yanhong Liu, Guangbin Li, Mingmin Zheng, Yusha Li, Anlei Zhang, Yingchun Zhang
Summary: Electrodeposited Cr coatings on carbon steel substrates using trivalent Cr salt exhibit good corrosion resistance in simulated nuclear power plant environments. Annealing at 200 degrees C can further enhance the corrosion resistance of the coatings. The Cr coatings significantly improve the flow accelerated corrosion (FAC) resistance of carbon steel substrates, with better performance observed for coatings annealed at 200 degrees C.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Materials Science, Coatings & Films
Ali Mardanifar, Ali Mohseni, Soheil Mahdavi
Summary: Electrodeposition of cobalt-chromium coatings with a thickness of around 25 μm was achieved from a trivalent chromium bath, followed by heat treatment at temperatures ranging from 200-800°C. The study revealed that heat treatment at 400°C resulted in the highest hardness and best tribological behavior, while also improving corrosion resistance.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Physical
Yujue Wang, Xiangui Zheng, Xiuyan Li
Summary: Electrodeposition is an effective method for synthesizing nanostructured metals with controlled microstructure. In this study, two different molecular weight types of polyethylene glycol (PEG) were used as additives for nickel electrodeposition. The addition of PEG played a crucial role in determining the microstructure of the deposits. The results showed that the microstructure transition of the Ni film was influenced by the current density and the molecular weight of PEG, leading to significant grain refinement.
APPLIED SURFACE SCIENCE
(2023)
Article
Electrochemistry
Masahiko Matsumiya, Yusuke Tsuchida, Ryoma Kinoshita, Yuji Sasaki
Summary: The study focused on developing solvent extraction and electrodeposition processes for platinum group metals to reduce waste volume. The electrodeposition behavior of Pt(IV) complex in a phosphonium-based ionic liquid was investigated, revealing charge transfer reactions and confirming the metallic state of the electrodeposits. Consecutive solvent extraction and electrodeposition cycles in the Alamine336/IL system showed high extraction percentage and good current efficiency.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Multidisciplinary Sciences
Tianyi Huang, Simone B. Moos, Edward A. Boyle
Summary: Research findings in the eastern tropical North Pacific (ETNP) oxygen-deficient zone (ODZ) support theoretical and experimental studies predicting that lighter chromium is preferentially reduced in low-oxygen environments and residual dissolved chromium becomes heavier due to removal of particl-reactive Cr(III) on sinking particles. Microbial activity, dependent on sinking organic matter flux, may be the dominant mechanism for chromium transformation, rather than a simple inorganic chemical conversion.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Ahlem Meziadi, Navid Zuberi, Hendrick W. de Haan, Marc A. Gauthier
Summary: This study reveals that the inefficiency of bioconjugation reactions, such as protein PEGylation, is caused by the excluded volume effect (EVE) between methoxy poly(ethylene glycol) (mPEG) and proteins. The researchers found that this EVE leads to the self-assembly of proteins and reactive mPEG into separate protein-rich and mPEG-rich domains. By adding unreactive low-molecular weight mPEG as a co-solvent, the association between the larger protein and reactive mPEG can be promoted, resulting in improved reaction efficiency.
Article
Electrochemistry
L. Buker, R. Boettcher, M. Leimbach, T. Hahne, R. Dickbreder, A. Bund
Summary: This study investigates the electrodeposition of thick chromium layers (>1 µm) from a trivalent electrolyte, aiming to find a suitable electrolyte composition for the deposition of hard functional coatings. The influence of different carboxylic acids on the deposition was examined, and it was found that the electrolyte containing malonic acid showed the most promising results for technical applications. Compared to hexavalent chromium, the trivalent chromium layer exhibited similar properties in terms of crack formation, hardness, and layer thickness (>1 µm).
ELECTROCHIMICA ACTA
(2022)
Article
Biochemistry & Molecular Biology
Antonio Ragusa, Veronica Lelli, Giuseppina Fanelli, Alessandro Svelato, Sara D'Avino, Federica Gevi, Criselda Santacroce, Piera Catalano, Mauro Ciro Antonio Rongioletti, Caterina De Luca, Alessandra Gulotta, Sara Rinalducci, Anna Maria Timperio
Summary: The placenta plays a crucial role in facilitating nutrient absorption, waste elimination, and other functions between the fetus and the maternal environment. In this study, a combination of ultra-high-performance liquid chromatography and mass spectrometry was used to detect polyethylene glycol (PEG) compounds in human placenta samples for the first time.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Materials Science, Multidisciplinary
J. Manoj Prabhakar, Rama Srinivas Varanasi, Caue Correa da Silva, Saba, Arnoud de Vooys, Andreas Erbe, Michael Rohwerder
Summary: Novel two-layer chromium-based coatings, consisting of a first layer containing chromium, oxygen, and carbon (Cr-O-C) and an oxygen-rich chromium oxide (Cr-O) topcoat, were electrodeposited from trivalent chromium electrolyte. The complex structure and composition of the coatings were studied using complementary characterization techniques, revealing the amorphous and oxygen-deficient nature of the electrodeposited oxide. In situ ambient pressure X-ray photoelectron spectroscopy and Raman spectroscopy confirmed the metastable nature of the oxide after heating to 450 degrees C, while cathodic delamination of a weak model polymer on these samples was studied using in situ scanning Kelvin probe.
Article
Electrochemistry
Minjie Hu, Youbin Wang, Zhiwen Chen, Shunyan Ning, Yuezhou Wei
Summary: The electrochemical behavior and electrodeposition mechanism of indium in acidic aqueous solution were investigated using cyclic voltammetry (CV) and chronoamperometry by electrochemical quartz crystal microbalance (EQCM). The CV curve of indium on Pt electrode showed additional reduction and oxidation peaks compared to that on glassy carbon (GC) electrode. EQCM results indicated simultaneous hydrogen reduction during indium electrodeposition on Pt electrode, while hydrogen evolution was suppressed on GC electrode. Passivation of indium and participation of low-valent indium ions were confirmed during the stripping of deposit on Pt electrode. The electrodeposition of indium on both GC and Pt followed progressive nucleation and three-dimensional growth controlled by diffusion, with calculated diffusion coefficients of In3+ on Pt and GC as (1.31 +/- 0.15)x10-5 cm2 s-1 and (1.2 +/- 0.1)x10-5 cm2 s-1, respectively. By separating the electrodeposition current using EQCM, the current characteristics of indium nucleation and growth can be reproduced, and the mass change signal recorded by EQCM fits well with the nonlinear fitting result.
ELECTROCHIMICA ACTA
(2023)
Article
Biochemical Research Methods
Shavkatjon Azizov, Mirkomil Sharipov, Jae-Min Lim, Salah M. Tawfik, Nuritdin Kattaev, Yong-Ill Lee
Summary: The study presents a novel microfluidic paper-based analytical device coupled with paper spray mass spectrometry for efficient and low-cost quantitative determination of C-18-ceramide as a prognostic biomarker. The device demonstrated high resistance to organic solvents and efficiency in sample analysis, achieving good recovery values in human serum samples. The method simplifies the experimental steps and operation process, allowing for the identification of subnanomolar concentrations of C-18-ceramide.
JOURNAL OF MASS SPECTROMETRY
(2021)
Review
Instruments & Instrumentation
Bui The Huy, Avvaru Praveen Kumar, Truong Thi Thuy, Nguyen Ngoc Nghia, Yong-Ill Lee
Summary: Upconversion fluorescence is the process of converting optical energy from low absorption energies to high emission energies. It has many advantages and is widely applied in the field of optics. Upconversion materials consist of low phonon host material and sensitizer-activator pair.
APPLIED SPECTROSCOPY REVIEWS
(2022)
Review
Chemistry, Multidisciplinary
Salah M. Tawfik, Shavkatjon Azizov, Mohamed R. Elmasry, Mirkomil Sharipov, Yong-Ill Lee
Summary: Nanomicelles as drug carriers show potential in selective and efficient drug delivery, forming organized structures through self-assembly and releasing drugs in response to various stimuli. The properties of core and corona forming blocks determine the size and shape of nanomicelles.
Article
Biochemical Research Methods
Ji-Yeon Kim, Woo Hong Joo, Dong-Soo Shin, Yong-Ill Lee, Chin Fen Teo, Jae-Min Lim
Summary: This study expanded the quantitative glycomic toolbox by optimizing the MILPIG approach in baker's yeast, demonstrating the requirement for carbon-13 labeled glucose incorporation and method robustness. The quantitation of the inhibitory effect of the N-linked glycosylation inhibitor tunicamycin on the yeast glycan expression profile was also performed.
ANALYTICAL BIOCHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Nguyen Ngoc Nghia, Bui The Huy, Pham Thanh Phong, Jin Sol Han, Dae Hyun Kwon, Yong-Ill Lee
Summary: A facile detection method of spermine was developed based on the fluorescence quenching of the ciprofloxacin-Tb3+ complex, showing high sensitivity and good linearity. Practical evaluation on human serum samples demonstrated the reliability and applicability of this method.
Article
Chemistry, Physical
Duy Quang Dao, Thi Chinh Ngo, Thi Thuy Huong Le, Quang Thang Trinh, Thi Le Anh Nguyen, Bui The Huy, Nguyen Ngoc Tri, Nguyen Tien Trung, Minh Tho Nguyen
Summary: SERS was employed to study the chemical enhancement mechanism of 2,4,5-T on a silver substrate, revealing stable adsorption configuration and electron transfer mechanism. The results are important for designing mobile sensors for rapid screening of toxic compounds.
JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Article
Chemistry, Multidisciplinary
Yuwei Liu, Xiaona Cui, Yong-Ill Lee, Hong-Guo Liu
Summary: This study systematically investigated the self-assembly behavior of polystyrene-block-poly(2-vinylpyridine) at the liquid/liquid interface. Different primary morphologies of aggregates were obtained depending on the molecular structure of the block copolymers and the amount of chloroauric acid. The findings provide valuable insights into the self-assembly behavior of block copolymers at interfaces and offer a facile approach for fabricating functional structures.
Review
Chemistry, Multidisciplinary
Zayakhuu Gerelkhuu, Yong-Ill Lee, Tae Hyun Yoon
Summary: This review describes the potential applications of upconversion nanomaterials (UCNMs) in biomedical fields, including drug delivery, bioimaging, biosensing, and photodynamic therapy. The mechanisms, synthesis methods, and biological toxicity of UCNMs are discussed, and the prospects for clinical applications are explored.
Article
Chemistry, Multidisciplinary
Seong-Soo Lee, Mirkomil Sharipov, Won June Kim, Yong-Ill Lee
Summary: Poly(ionic liquids) (PILs) have been widely used for CO2 capture due to their resemblance to ionic liquids and properties of polymers. In this study, the amine-functionalized poly(vinylimidazole)-based PIL (PVIm-NH2) was successfully prepared and characterized as a chemosensor for CO2 gas detection. The detection limit of PVIm-NH2 in the presence of triethylamine (TEA) was found to be 2.86 x 10-3 M with R2 = 0.9906. The mechanism of PVIm-NH2 generating N-heterocyclic carbenes (NHCs) in the presence of TEA and their reaction with CO2 gas to form a carboxylic acid was investigated. Structural modifications of PIL were also shown to make it a promising candidate for chemosensor applications.
Article
Biotechnology & Applied Microbiology
Salah M. Tawfik, Atef S. Kobisy, Emad A. Badr, Ahmed H. Elged, Yong-Ill Lee
Summary: Microbial corrosion caused by microorganisms in the petroleum industry is a significant problem that can have severe environmental and economic consequences. Therefore, the development of innovative nonionic porous antimicrobial materials with diverse hydrophobic conjugated motifs is highly desirable.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Review
Chemistry, Analytical
The Huy Bui, Joong Ho Shin
Summary: Perovskite materials have unique electronic and optical properties, making them highly suitable for electronic and optical devices. They show potential in sensor applications, including photodetection for medical diagnostics and gas sensing for industrial process control and environmental monitoring. However, the challenge lies in their stability in the presence of moisture or oxygen. This study provides a comprehensive evaluation of recent applications of perovskite materials-based sensors, giving valuable insights into their potential for innovative sensor technologies.
MICROCHEMICAL JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Phommachith Sonexai, Minh Van Nguyen, Bui The Huy, Yong -Ill Lee
Summary: The detection of harmful chemicals in the environment and for food safety is important, but traditional techniques are expensive and time-consuming. Surface-enhanced Raman spectroscopy (SERS) offers a powerful alternative for detecting low concentrations of chemical compounds and biomolecules. This study presents a reproducible method for producing Ag nanoparticles that can be used to create highly sensitive SERS substrates. The developed SERS substrate exhibits exceptional analytical performance and has the potential to be a valuable analytical tool for monitoring environmental contaminants.
BEILSTEIN JOURNAL OF NANOTECHNOLOGY
(2023)
Review
Chemistry, Analytical
The Huy Bui, Balamurugan Thangavel, Mirkomil Sharipov, Kuangcai Chen, Joong Ho Shin
Summary: Traditionally, analytical chemistry and diagnosis relied on wet laboratories and skilled professionals utilizing sophisticated instruments for sample handling and analysis. However, the development of novel materials and sensing techniques has led to a significant shift towards the use of standalone sensors, especially those integrated into smartphones. This review explores recent advancements in smartphone-based sensors, covering both optical and electrochemical sensing methods and highlighting their potential impact in chemical and biological analyses.
Article
Nanoscience & Nanotechnology
Mirkomil Sharipov, Soojin Hwang, Won June Kim, Bui The Huy, Salah M. Tawfik, Yong -Ill Lee
Summary: This study investigates the effect of solvent blends on the structure and phase of perovskites and develops a new synthetic approach for water-stable CsPbBr3 particles. Different solvent blends result in various lead bromide species and different forms of perovskites.
ADVANCES IN NANO RESEARCH
(2022)
Article
Chemistry, Analytical
Michel Rocha Baqueta, Augusto Cesar Costa-Santos, Ana Paula Rebellato, Gisele Marcondes Luz, Juliana Azevedo Lima Pallone, Federico Marini, Alexsandro Lara Teixeira, Douglas N. Rutledge, Patricia Valderrama
Summary: This study reports the essential element composition of new Brazilian Canephora coffees and applies chemometric tools for analysis. The results demonstrate the suitability of this method for origin and species discrimination based on the inorganic fraction of coffee.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mengjie Li, Jiapeng Wang, You Zhou, Yang Chen, Lingying Xia
Summary: A novel photoelectrochemical biosensor based on gold nanoparticles and specific structures was developed for highly sensitive detection of mercury ion. The multiple sandwich structures hindered electron supply and light harvesting, resulting in a weakened PEC signal, while the specific structures extinguished the PEC signal, enabling quantitative detection of Hg2+. The sensor exhibited high selectivity and stability, with potential applications in environmental detection, biological analysis, and medical research.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Mohamed A. Korany, Rasha M. Youssef, Marwa A. A. Ragab, Mostafa A. Afify
Summary: A stability-indicating fit-for-purpose method was developed for the determination of HC, TL, and PS in syrup dosage form. The method successfully separated CL from THY and quantified the analytes using HPLC-DAD. The robustness of the method was assessed through statistical analysis and self-validation.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Lingling Lin, Minyu Li, Ping Li, Chenqing Ye, Huanglong Zhuang, Shaohuang Weng, Feng Chen
Summary: This study developed a highly sensitive and selective electrochemical sensor for simultaneous detection of dopamine and uric acid. The sensor exhibited excellent anti-interference and stability, and could accurately measure dopamine and uric acid in human urine samples.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Peifang Chen, Caiyun Jiang, Zhouping Wang, Hong-zhen Lian, Xiaoyuan Ma
Summary: In this study, a high-performance SERS-active aptasensor was successfully developed for the quantitative analysis of AFB1 in cereal grains, which is of great significance in the field of food safety.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
E. Abas, C. Marina-Montes, C. Perez-Marin, J. Puimedon, J. Anzano
Summary: This study conducted a comprehensive measurement of natural and anthropogenic radionuclides in soil, water, and air in different locations around Deception Island in Antarctica. The results revealed significant levels of 210Pb and anthropogenic 137Cs in soil samples near old human settlements and facilities, as well as detectable levels of 137Cs and 60Co in water samples from old hunting areas. The findings also suggested potential resuspension processes based on higher-than-expected air quality results.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Joao Franciso Allochio, Nayara A. dos Santos, Nathalia dos S. Conceicao, Clara S. D. Baptista, Keyller B. Borges, Valdemar Lacerda Jr, Wanderson Roma
Summary: This study developed a fiber spray ionization mass spectrometry (FSI-MS) method, which shows great potential in detecting illicit drugs. Compared with paper spray ionization mass spectrometry (PSI-MS), FSI-MS demonstrates higher sensitivity in COC detection.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Dina A. Ahmed, Ola G. Hussein, Mamdouh R. Rezk, Mohamed Abdelkawy, Yasmin Rostom
Summary: The main goal of this study was to develop two green chromatographic techniques, HPLC and TLC, for the determination of alcaftadine (ALF) in pharmaceutical formulation and biological samples. The developed HPLC technique showed high efficiency and minimal environmental impact, successfully identifying ALF in the presence of its degradate. The TLC method provided a stability indicating study for ALF and was determined to be safe, green, and eco-friendly.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Abdullah Taner Bisgin
Summary: A green, speedy, and handy method for separation and determination of four commonly used food colorants was established using vortex assisted sequential-simultaneous liquid phase micro-extraction (VA-SS-LPME). The method does not require any instrumental chromatographic techniques. The procedure includes sequential separation steps using different extractants and simultaneous UV-vis spectrophotometric determination steps. The method is environmentally friendly and applicable for determination of colorants in food and pharmaceuticals.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Yifan Zhang, Tong Zhang, Wenjing Ba, Li Liu, Yuan Rao, Xiaodan Zhang, Hanhan Zhang, Xiu Jin
Summary: This paper proposes a novel spectral transfer modelling method based on neural network architecture searching for the asymptomatic prediction of Akizuki pear cork spot disorder. The experiments show that the model by this method is more effective, achieving an accuracy of 82.61%.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Krzysztof Greda, Maja Welna, Anna Szymczycha-Madeja, Pawel Pohl
Summary: For the first time, a dispersive micro-solid phase extraction (D-mu SPE) based on graphene oxide was used for the ultrasensitive determination of Cd. With this method, Cd can be efficiently extracted from a mixture of alkali and alkaline earth metals without the need for an elution step. The combination of D-mu SPE and SAGD OES significantly reduces matrix effects and improves the tolerance of Cd to alkali metals. The method shows simplicity in the measurement system and the commercially available nanosorbent used.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
P. K. Fathima Anjila, G. R. Tharani, Anand Sundaramoorthy, Venkat Kumar Shanmugam, Karthikeyan Subramani, Shanmugavel Chinnathambi, Ganesh N. Pandian, Vimala Raghavan, Andrews Nirmala Grace, Singaravelu Ganesan, Mangaiyarkarasi Rajendiran
Summary: This work proposes a rapid and sensitive spectroscopic method for detecting melamine in food products using rare-earth Terbium-doped Graphene Quantum Dots (Tb-GQDs) synthesized by microwave and simple chemical conjugation methods. The synthesized Tb-GQDs show a spherical shape with a size of approximately 6 nm and a quantum yield of 52%. The maximum detection limit for melamine concentration in milk and milk products is found to be 0.31 μM. The dual emitting Tb-GQDs provide a sensitive and effective platform for real-time detection of melamine in food samples, particularly in milk, and show promising potential in the food industry.
MICROCHEMICAL JOURNAL
(2024)
Review
Chemistry, Analytical
Piyush Dey, Mandeep Kaur, Akhil Khajuria, Dilmeet Kaur, Manpreet Singh, Hema Kumari Alajangi, Neha Singla, Gurpal Singh, Ravi Pratap Barnwal
Summary: Environmental issues, such as the uncontrolled release of dangerous pollutants, have significant impacts on human health. Traditional methods for detecting pollutants require specialized personnel and equipment, but nanotechnology has improved the performance of biosensors. This article discusses the use of nanotechnology in pollutant detection and the associated techniques.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Sa Dong, Qiuyun Shi, Lingjun Guan, Yulong Wang, Pengyan Liu, Cunzheng Zhang, Jianguo Feng
Summary: In this study, a highly sensitive indirect competitive chemiluminescence enzyme immunoassay (icCLEIA) method was developed for the determination of sodium pentachlorophenolate (PCP-Na) and its metabolite pentachlorophenol (PCP). The method showed high specificity and affinity with a detection limit of 0.0032 ng/mL for PCP-Na and 0.0192 ng/mL for PCP. The method had no cross reaction with other chlorophenols compounds except for PCP. The average recoveries in chicken, pork and fish samples were 81.3-105.8% with low coefficient of variation (CV).
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Analytical
Palaniappan Ilayaraja, Murugan Manivannan, Paramasivam Parthiban
Summary: Nirmatrelvir, an antiviral drug used for the treatment of COVID-19, has been recommended by the World Health Organization. We developed an optimized analytical method for the quantification of Nirmatrelvir and its products, with high sensitivity and a wide linear range. The method also meets the requirements for greenness evaluation.
MICROCHEMICAL JOURNAL
(2024)
