A novel approach to generate a recombinant toxoid vaccine against Clostridium difficile

Fidaxomicin for the Treatment of Clostridium difficile Infections

(2012) C. B. Whitman et al.   ANNALS OF PHARMACOTHERAPY

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

(2012) Ana Antunes et al.   NUCLEIC ACIDS RESEARCH

Secretion of Clostridium difficile Toxins A and B Requires the Holin-like Protein TcdE

(2012) Revathi Govind et al.   PLoS Pathogens

Clostridium difficile Toxin B Causes Epithelial Cell Necrosis through an Autoprocessing-Independent Mechanism

(2012) Nicole M. Chumbler et al.   PLoS Pathogens

Cytotoxicity ofClostridium difficiletoxin B does not require cysteine protease-mediated autocleavage and release of the glucosyltransferase domain into the host cell cytosol

(2012) Shan Li et al.   Pathogens and Disease

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B

(2011) Selda Genisyuerek et al.   MOLECULAR MICROBIOLOGY

Fidaxomicin versus Vancomycin forClostridium difficileInfection

(2011) Thomas J. Louie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Repetitive domain of Clostridium difficile toxin B exhibits cytotoxic effects on human intestinal epithelial cells and decreases epithelial barrier function

(2010) Mateja Zemljic et al.   ANAEROBE

The role of toxin A and toxin B in Clostridium difficile infection

(2010) Sarah A. Kuehne et al.   NATURE

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production

(2009) S. Underwood et al.   JOURNAL OF BACTERIOLOGY

A modular system for Clostridium shuttle plasmids

(2009) John T. Heap et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Production of Clostridium difficile toxin in a medium totally free of both animal and dairy proteins or digests

(2009) A. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells

(2008) R. Gerhard et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY