Article
Microbiology
Eizo Takahashi, Sadayuki Ochi, Tamaki Mizuno, Daichi Morita, Masatomo Morita, Makoto Ohnishi, Hemanta Koley, Moumita Dutta, Goutam Chowdhury, Asish K. Mukhopadhyay, Shanta Dutta, Shin-Ichi Miyoshi, Keinosuke Okamoto
Summary: Three NAG vibrio strains isolated from pond water in Kolkata, India were found to potentially possess virulence factors that can induce severe syndrome, indicating a possible risk of future epidemics caused by these virulent NAG vibrios.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Infectious Diseases
Ying Zhao, Tingting He, Bowen Tu, Xujian Mao, Jingyi Jiang, Xia Jiang, Fengming Wang, Min Wang, Yu Wang, Hongyan Sun
Summary: This study reported a case of multi-organ lesions caused by non-O1/non-O139 Vibrio cholerae. The case indicated that under good sanitary conditions, serogroups may enhance pathogenicity by attacking the tight junction of small intestinal epithelial cells, leading to bacteremia and potential death within 48-72 hours. Therefore, laborers engaged in agricultural production may be at risk of V. cholerae infection through exposure to contaminated water sources.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Ecology
Yun Luo, Henghui Wang, Jie Liang, Huiqin Qian, Julian Ye, Lixia Chen, Xianqing Yang, Zhongwen Chen, Fei Wang, Sophie Octavia, Michael Payne, Xiaojun Song, Jianmin Jiang, Dazhi Jin, Ruiting Lan
Summary: This study investigated the presence of non-O1/non-O139 Vibrio cholerae in river water samples from Jiaxing and Jiande in Zhejiang, China, revealing multidrug resistance and diverse population structures. The findings suggest that these strains may pose a potential threat to human health, highlighting the importance of routine surveillance of non-O1/non-O139 V. cholerae in freshwater rivers.
Article
Immunology
Pan Lu, Jialiang Chen, Zhenpeng Li, Zhe Li, Jingyun Zhang, Biao Kan, Bo Pang
Summary: In this study, a CARID system was developed for rapid detection of toxigenic V. cholerae serogroups. The system showed rapid, sensitive, economically efficient, and portable features, and was suitable for detecting complex samples.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Katarzyna Schmidt, Holger C. Scholz, Sandra Appelt, Jana Michel, Daniela Jacob, Susann Dupke
Summary: Global warming has led to an increase in Vibrio species in various aquatic environments, and this study focuses on the virulence and resistance patterns of Vibrio cholerae non-O1/non-O139 strains from Germany and other European countries. The results show high genetic diversity among the non-O1/non-O139 isolates, with some closely related isolates suggesting an epidemiological link. The study identifies virulence genes and profiles in the isolates and reveals the presence of antibiotic resistance genes, including carbapenemase genes, in fresh water. Monitoring antimicrobial resistance is crucial for public health authorities to minimize risks for the human population.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Quantao Zhang, Thomas Alter, Eckhard Strauch, Jens Andre Hammerl, Keike Schwartz, Maria Borowiak, Carlus Deneke, Susanne Fleischmann
Summary: This study characterized the virulence potential of NOVC strains isolated from retail seafood at both genotypic and phenotypic levels. The results showed differences in the virulence potential among the analyzed strains, which may have implications for future seafood monitoring and risk assessment.
Article
Infectious Diseases
Jinrong Tang, Sheng Li, Manli Zhang, Fengzhi Li, Ying Tang, Fangfang Yang
Summary: This report presents a case of non-O1, non-O139 Vibrio cholerae infection in a patient with cirrhosis, highlighting the importance of paying attention to the pathogenicity of strains with few virulence genes.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Medicine, General & Internal
Mingjie Wu, Liangjing Zhou, Liping Cao
Summary: Acute hemorrhagic necrotizing enterocolitis (AHNE) is a rapidly progressive and extremely dangerous disease that can lead to multi-organ failure. This study reports a rare case caused by Vibrio cholerae and highlights the diagnostic and treatment process.
Article
Microbiology
Murari Bhandari, Irani U. U. Rathnayake, Flavia Huygens, Amy V. V. Jennison
Summary: This study characterized V. cholerae strains from Queensland, Australia and compared them to environmental strains. The study revealed that Queensland waterways can harbor diverse V. cholerae strains with virulence genes, which may be shared through gene transfer. The findings emphasize the importance of routine monitoring and genomic analysis of these strains.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Lili Yan, Yinzhe Jin, Beiyu Zhang, Yingwei Xu, Xu Peng, Si Qin, Lanming Chen
Summary: This study investigated the impact of aquatic animal matrices on the growth and pathogenicity of Vibrio cholerae. It found that these matrices significantly increased bacterial biomass and induced distinct secretomes and proteomes, including virulence- and resistance-associated proteins.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Xiaojian Gao, Zirui Zhang, Qieqi Qian, Qiyun Chen, Shuwen Gu, Jie Li, Yingjie Zhang, Congcong Wu, Qun Jiang, Xiaojun Zhang
Summary: Non-O1/O139 Vibrio cholerae can survive under starvation stress for a long period of time and cause disease by altering cell structure, upregulating stress resistance-related genes, and downregulating flagellum assembly-related genes. This knowledge can contribute to the development of intervention strategies for controlling non-O1/O139 V. cholerae infection in aquaculture.
MICROBIOLOGY SPECTRUM
(2022)
Article
Fisheries
Manoharmayum Shaya Devi, Prasenjit Paria, Vikash Kumar, Pranaya Kumar Parida, Praveen Maurye, Bijay Kumar Behera, Basanta Kumar Das
Summary: This study identified a non-pathogenic serotype of Vibrio cholerae isolated from an Indian wetland system, emphasizing the importance of proper management in preventing diseases in aquaculture.
Article
Microbiology
Mahendra Singh, N. Rupesh, Shashi Bhushan Pandit, Kausik Chattopadhyay
Summary: In this study, it was found that curcumin can neutralize the membrane-damaging activity of VCC, making it a potential inhibitor of this powerful bacterial toxin. Curcumin binds to VCC and reduces its ability to attack cell membranes, while the soluble extract of curcumin generated by heat treatment weakens the pore-forming activity of VCC.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Veterinary Sciences
Yifan Zhou, Shuwen Gu, Jie Li, Peng Ji, Yingjie Zhang, Congcong Wu, Qun Jiang, Xiaojian Gao, Xiaojun Zhang
Summary: This study sequenced the whole genome of non-O1/O139 Vibrio cholerae GXFL1-4, isolated from Macrobrachium rosenbergii, to investigate its virulence and antibiotic resistance. The results revealed a complex molecular mechanism of pathogenicity and antibiotic resistance in this strain. The findings provide important insights into the pathogenesis of non-O1/O139 V. cholerae and may contribute to the development of prevention and treatment strategies.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Infectious Diseases
Dongmei Yan, Mingzhong Sun, Lihua Xiao, Hongmei Chen, Qisi Zhang, Yaru Zhi, Qingping Fu
Summary: This study reports a rare case of intestinal coinfection with non-O1/O139 Vibrio cholerae and Salmonella typhimurium, along with V. cholerae septicemia. The data suggests that the presence of S. typhimurium may enhance the virulence of V. cholerae and inhibit the growth of S. typhimurium in vitro.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
(2023)
Article
Genetics & Heredity
Maria Belen Federico, Maria Belen Vallerga, Analia Radl, Natalia Soledad Paviolo, Jose Luis Bocco, Marina Di Giorgio, Gaston Soria, Vanesa Gottifredi
Article
Infectious Diseases
Paulo R. Cortes, Laura S. Chiapello, David Dib, Monica V. Herrero, Carmen T. Nuncira, Carlos De Petris, Jose Echenique
PLOS NEGLECTED TROPICAL DISEASES
(2016)
Article
Multidisciplinary Sciences
Jenniffer Puerta Suarez, Leonardo R. Sanchez, Florencia C. Salazar, Hector A. Saka, Rosa Molina, Andrea Tissera, Virginia E. Rivero, Walter D. Cardona Maya, Ruben D. Motrich
SCIENTIFIC REPORTS
(2017)
Article
Microbiology
German E. Pinas, Nicolas M. Reinoso-Vizcaino, Nubia Y. Yandar Barahona, Paulo R. Cortes, Rosario Duran, Chandan Badapanda, Ankita Rathore, Dario R. Bichara, Melina B. Cian, Nadia B. Olivero, Daniel R. Perez, Jose A. Echenique
Article
Immunology
Alejandro J. Moyano, Ana C. Racca, Gaston Soria, Hector A. Saka, Veronica Andreoli, Andrea M. Smania, Claudia Sola, Jose L. Bocco
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2018)
Article
Multidisciplinary Sciences
Marianela C. Serradell, Lucia L. Rupil, Roman A. Martino, Cesar G. Prucca, Pedro G. Carranza, Alicia Saura, Elmer A. Fernandez, Pablo R. Gargantini, Albano H. Tenaglia, Juan P. Petiti, Renata R. Tonelli, Nicolas Reinoso-Vizcaino, Jose Echenique, Luciana Berod, Eliane Piaggio, Bertrand Bellier, Tim Sparwasser, David Klatzmann, Hugo D. Lujan
NATURE COMMUNICATIONS
(2019)
Article
Microbiology
Maria E. Panzetta, Agustin L. Lujan, Robert J. Bastidas, Maria T. Damiani, Raphael H. Valdivia, Hector A. Saka
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Microbiology
Nicolas M. Reinoso-Vizcaino, Melina B. Cian, Paulo R. Cortes, Nadia B. Olivero, Mirelys Hernandez-Morfa, German E. Pinas, Chandan Badapanda, Ankita Rathore, Daniel R. Perez, Jose Echenique
Article
Paleontology
Dario Alejandro Ramirez, Hector Alex Saka, Rodrigo Nores
Summary: This study confirmed at least one individual in a mass grave in Cordoba, Argentina, was a victim of the fifth cholera pandemic by analyzing ancient DNA samples. The combination of multiple lines of evidence strengthened the understanding of the presence, effects, and potential evolutionary paths of the disease in the past.
INTERNATIONAL JOURNAL OF PALEOPATHOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Maria Fernanda Suarez, Jose Echenique, Juan Manuel Lopez, Esteban Medina, Mariano Iros, Horacio M. Serra, M. Elizabeth Fini
Summary: Genomic analysis reveals differences in genetic stability and immune response between pterygium and pinguecula, both of which are associated with inflammation. While DEGs are linked to cancer, both conditions remain benign, showing well-differentiated and non-invasive characteristics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Nadia B. Olivero, Ana S. Gonzalez-Reiche, Viviana E. Re, Gonzalo M. Castro, Maria B. Pisano, Paola Sicilia, Maria G. Barbas, Zenab Khan, Adriana van de Guchte, Jayeeta Dutta, Paulo R. Cortes, Mirelys Hernandez-Morfa, Victoria E. Zappia, Lucia Ortiz, Ginger Geiger, Daniela Rajao, Daniel R. Perez, Harm van Bakel, Jose Echenique
Summary: This study describes the association of clinical characteristics with the clinical outcomes of survivors and non-survivors of COVID-19 patients, and the specific mutations found in the genome sequences of SARS-CoV-2 in each patient group. The results show the selective nature of SARS-CoV-2 mutations in different patient groups and provide new genomic data on the virus evolution.
Article
Microbiology
Mirelys Hernandez-Morfa, Nicolas M. Reinoso-Vizcaino, Nadia B. Olivero, Victoria E. Zappia, Paulo R. Cortes, Andrea Jaime, Jose Echenique
Summary: This study reveals the fluoroquinolone persistence mechanism in Streptococcus pneumoniae, which is induced by oxidative stress and allows the bacteria to survive in host cells. The findings suggest that persistence may influence antibiotic therapy and contribute to the evolution of fluoroquinolone resistance.
MICROBIOLOGY SPECTRUM
(2022)
Article
Biology
Julieta Martino, Sebastian Omar Siri, Nicolas Luis Calzetta, Natalia Soledad Paviolo, Cintia Garro, Maria F. Pansa, Sofia Carbajosa, Aaron C. Brown, Jose Luis Bocco, Israel Gloger, Gerard Drewes, Kevin P. Madauss, Gaston Soria, Vanesa Gottifredi
Summary: Inhibiting ROCK independently triggers synthetic lethality in BRCA2-deficient cells, which is different from the synthetic lethality caused by PARP inhibitors. Cytokinesis failure induces mitotic abnormalities and synthetic lethality in BRCA2-deficient cells.
Article
Infectious Diseases
Flavio G. Lipari, Daniela Hernandez, Mario Vilaro, Juan P. Caeiro, Hector Alex Saka
REVISTA CHILENA DE INFECTOLOGIA
(2020)
Review
Developmental Biology
Juan Pablo Mackern-Oberti, Ruben Dario Motrich, Maria Teresa Damiani, Hector Alex Saka, Cristian Andres Quintero, Leonardo Rodolfo Sanchez, Tamara Moreno-Sosa, Carolina Olivera, Cecilia Cuffini, Virginia Elena Rivero