A single mutation in the core domain of the lac repressor reduces leakiness

Cell-free translation of peptides and proteins:from high throughput screening to clinical production

(2013) Christopher J Murray et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Expression in Escherichia coli: becoming faster and more complex

(2013) Renaud Vincentelli et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cell-free expression—making a mark

(2013) Frank Bernhard et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Allostery and the lac Operon

(2013) Mitchell Lewis   JOURNAL OF MOLECULAR BIOLOGY

Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression

(2012) Sarah Meinhardt et al.   NUCLEIC ACIDS RESEARCH

A synthetic biology approach to self-regulatory recombinant protein production in Escherichia coli

(2012) Martin Dragosits et al.   Journal of Biological Engineering

Altering Residues N125 and D149 Impacts Sugar Effector Binding and Allosteric Parameters inEscherichia coliLactose Repressor

(2011) Jia Xu et al.   BIOCHEMISTRY

Bacterial expression systems for recombinant protein production: E. coli and beyond

(2011) Rachel Chen   BIOTECHNOLOGY ADVANCES

Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology

(2011) Pietro Gatti-Lafranconi et al.   FEBS Journal

A Tale of Two Repressors

(2011) Mitchell Lewis   JOURNAL OF MOLECULAR BIOLOGY

Thermodynamic Analysis of Mutant lac Repressors

(2011) Robert Daber et al.   JOURNAL OF MOLECULAR BIOLOGY

Optimizing HIV-1 protease production in Escherichia coli as fusion protein

(2011) Federica Volontè et al.   Microbial Cell Factories

Increasing recombinant protein production in Escherichia coli K12 through metabolic engineering

(2011) Hendrik Waegeman et al.   New Biotechnology

Protein folding and aggregation in bacteria

(2010) Raimon Sabate et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Flexibility in the Inducer Binding Region Is Crucial for Allostery in theEscherichia coliLactose Repressor

(2009) Jia Xu et al.   BIOCHEMISTRY

Allostery in the LacI/GalR family: variations on a theme

(2009) Liskin Swint-Kruse et al.   CURRENT OPINION IN MICROBIOLOGY

A Novel Molecular Switch

(2009) Robert Daber et al.   JOURNAL OF MOLECULAR BIOLOGY

Components of the E. coli envelope are affected by and can react to protein over-production in the cytoplasm

(2009) Riccardo Villa et al.   Microbial Cell Factories

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Subdividing Repressor Function: DNA Binding Affinity, Selectivity, and Allostery Can Be Altered by Amino Acid Substitution of Nonconserved Residues in a LacI/GalR Homologue†

(2008) Hongli Zhan et al.   BIOCHEMISTRY

Evolving Lac repressor for enhanced inducibility

(2008) O. Satya Lakshmi et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Strict regulation of gene expression from a high-copy plasmid utilizing a dual vector system

(2008) David F. Gruber et al.   PROTEIN EXPRESSION AND PURIFICATION

Ligand-induced Conformational Changes and Conformational Dynamics in the Solution Structure of the Lactose Repressor Protein

(2007) Marc Taraban et al.   JOURNAL OF MOLECULAR BIOLOGY