期刊
MICROBES AND INFECTION
卷 14, 期 1, 页码 17-25出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.micinf.2011.08.019
关键词
Surfactant; Collectin; Phospholipid; Infection
资金
- US Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Biomedical Laboratory Research and Development
- US Department of Veterans Affairs
- National Institutes of Health [HL096376, HL097376, HL098174]
Pulmonary surfactant is a complex surface-active substance comprised of key phospholipids and proteins that has many essential functions. Surfactant's unique composition is integrally related to its surface-active properties, its critical role in host defense, and emerging immunomodulatory activities ascribed to surfactant lipids. Together these effector functions provide for lung stability and protection from a barrage of potentially virulent infectious pathogens. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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