4.6 Review

Non-apoptotic functions of cell death effectors in inflammation and innate immunity

期刊

MICROBES AND INFECTION
卷 14, 期 14, 页码 1241-1253

出版社

ELSEVIER
DOI: 10.1016/j.micinf.2012.06.005

关键词

Innate immunity; Apoptosis; Pattern recognition receptors; Mitochondria

资金

  1. Canadian Institutes of Health Research (CIHR)
  2. Canadian Cancer Society Research Institute (CCSRI)
  3. Canada Foundation for Innovation (CFI)
  4. Burroughs Wellcome Fund
  5. CHIR/Canadian Association for Gastroenterology (CAG)/Abbott fellowship

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Innate immunity and cell death are essential host defense mechanisms. Mounting evidence reveals that these processes an: closely linked. The aim of this review is to highlight the close relationship between the pathways governing these processes, particularly how regulators of cell death control the induction of the innate immune response. (C) 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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