Uncovering the global host cell requirements for influenza virus replication via RNAi screening

Influenza virus is reliant on numerous host cell functions during its replication cycle. RNA interference technology, applied on a genome-wide level, has identified human host factors that are necessary for efficient virus replication and provides new insight into how influenza virus interacts with its host at the molecular level. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.