Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development

CD4+ T Cells Modulate Expansion and Survival but Not Functional Properties of Effector and Memory CD8+ T Cells Induced by Malaria Sporozoites

(2011) Michael G. Overstreet et al.   PLoS One

Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

(2011) Ian A. Cockburn et al.   PLoS Pathogens

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Genetically engineered, attenuated whole-cell vaccine approaches for malaria

(2010) Ashley Vaughan et al.   Human vaccines & immunotherapeutics

From the circumsporozoite protein to the RTS,S/AS candidate vaccine

(2010) Joe Cohen et al.   Human vaccines & immunotherapeutics

Malaria Vaccine Design: Immunological Considerations

(2010) Michael F. Good et al.   IMMUNITY

Protein-DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses

(2010) X. Wu et al.   JOURNAL OF IMMUNOLOGY

Differential Effector Pathways Regulate Memory CD8 T Cell Immunity against Plasmodium berghei versus P . yoelii Sporozoites

(2010) Noah S. Butler et al.   JOURNAL OF IMMUNOLOGY

Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation

(2010) Kevin N. Couper et al.   PLoS Pathogens

Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

(2010) Ian A. Cockburn et al.   PLoS Pathogens

CpG-enhanced CD8+ T-cell responses to peptide immunization are severely inhibited by B cells

(2009) Michael G. Overstreet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel Subset of CD8 + Dendritic Cells Localized in the Marginal Zone Is Responsible for Tolerance to Cell-Associated Antigens

(2009) C.-H. Qiu et al.   JOURNAL OF IMMUNOLOGY

Genetically Attenuated Parasite Vaccines Induce Contact-Dependent CD8+ T Cell Killing of Plasmodium yoelii Liver Stage-Infected Hepatocytes

(2009) A. Trimnell et al.   JOURNAL OF IMMUNOLOGY

Langerin+CD8 + Dendritic Cells Are Critical for Cross-Priming and IL-12 Production in Response to Systemic Antigens

(2009) K. J. Farrand et al.   JOURNAL OF IMMUNOLOGY

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

(2009) Kent E. Kester et al.   JOURNAL OF INFECTIOUS DISEASES

Dendritic cell subsets in primary and secondary T cell responses at body surfaces

(2009) William R Heath et al.   NATURE IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Immunization with Radiation-Attenuated Plasmodium berghei Sporozoites Induces Liver cCD8α+DC that Activate CD8+T Cells against Liver-Stage Malaria

(2009) Ousman Jobe et al.   PLoS One

In Vivo Induction of Immune Responses to Pathogens by Conventional Dendritic Cells

(2008) María López-Bravo et al.   IMMUNITY

Inflammasomes: guardians of cytosolic sanctity

(2008) Mohamed Lamkanfi et al.   IMMUNOLOGICAL REVIEWS

Effector CD8+ T Lymphocytes against Liver Stages of Plasmodium yoelii Do Not Require Gamma Interferon for Antiparasite Activity

(2008) S. Chakravarty et al.   INFECTION AND IMMUNITY

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY

Processing of the circumsporozoite protein in infected hepatocytes is not dependent on aspartic proteases

(2008) S. E. BONGFEN et al.   PARASITE IMMUNOLOGY

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

(2008) M. L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria

(2008) N. W. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA