期刊
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
卷 45, 期 12, 页码 2346-2352出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/MSS.0b013e31829a726a
关键词
NIRS; MITOCHONDRIAL CAPACITY; OXIDATIVE METABOLISM; ENDURANCE TRAINING; DETRAINING
资金
- National Institutes of Health [HD-039676]
- University of Georgia Graduate School intramural grants
Purpose: Previous studies have used near-infrared spectroscopy (NIRS) to measure skeletal muscle mitochondrial capacity. This study tested the hypothesis that NIRS-measured mitochondrial capacity would improve with endurance exercise training and decline with detraining. Methods: Nine young participants performed 4 wk of progressively increasing endurance exercise training of the wrist flexor muscles followed by approximately 5 wk of inactivity. The rate of recovery of muscle oxygen consumption (m(V) over dotO(2)) was measured with NIRS every 3-7 d, indicating mitochondrial oxidative capacity. Results: A linear increase in mitochondrial capacity (NIRS rate constant) was found with a group average of 64% +/- 37% improvement after 4 wk of exercise training (P < 0.05). Mitochondrial capacity declined exponentially upon cessation of exercise training, with a mean half-time of approximately 7.7 d. Conclusions: Both the magnitude and the time course of mitochondrial adaptations to exercise training and detraining measured with NIRS was consistent with previous studies using both in vitro and in vivo techniques. These findings show that NIRS-based measurements can detect meaningful changes in mitochondrial capacity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据