Article
Sport Sciences
Peter Krustrup, Magni Mohr, Lars Nybo, Dimitrios Draganidis, Morten B. Randers, Georgios Ermidis, Christina Orntoft, Line Roddik, Dimitrios Batsilas, Athanasios Poulios, Niels Ortenblad, Georgios Loules, Charikleia K. Deli, Alexios Batrakoulis, Jakob L. Nielsen, Athanasios Z. Jamurtas, Ioannis G. Fatouros
Summary: The study investigated skeletal muscle metabolism and repeated sprint performance changes in elite female football players during match play. The results showed marked glycogen depletion in both fiber types at the end of the match, potentially explaining fatigue. Repeated sprint ability decreased after intense periods in both halves, possibly due to muscle metabolite perturbations.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2022)
Article
Multidisciplinary Sciences
Hamish Ferguson, Chris Harnish, Sebastian Klich, Kamil Michalik, Anna Katharina Dunst, Tony Zhou, J. Geoffrey Chase
Summary: The current convention that peak power is the main determinant of sprint cycling performance is challenged by this study. It compares two common durations of sprint cycling performance, not only based on peak power but also power over 20 minutes. Despite the belief that longer maximal efforts could hinder sprint cycling performance, the study finds strong relationships between 1-second power and longer durations up to 20 minutes, suggesting the importance of training durations from 1 second to 20 minutes to improve competition performance.
Article
Sport Sciences
Mathew J. Mildenhall, Ed Maunder, Daniel J. Plews, Michael I. Lindinger, Simeon P. Cairns
Summary: This study aimed to investigate the effect of plasma acidosis on mechanical performance and whether bicarbonate supplementation can attenuate plasma acidosis and arterial oxygen desaturation in elite cyclists. The results showed that plasma acidosis was not associated with the decline of peak power output, and bicarbonate supplementation failed to improve arterial oxygen desaturation or mechanical performance.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Physiology
Jeppe Panduro, Jeppe F. Vigh-Larsen, Georgios Ermidis, Susana Povoas, Jakob Friis Schmidt, Karen Sogaard, Peter Krustrup, Magni Mohr, Morten Bredsgaard Randers
Summary: This study aimed to examine the acute metabolic response in upper and lower body skeletal muscle to football training organized as small-sided games (SSG). The results showed changes in muscle glycogen and lactate concentration in both upper and lower body muscles after football training, but the acute metabolic changes did not explain the previously reported training effect in the upper extremities.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Physiology
M. Massidda, L. Flore, N. Kikuchi, M. Scorcu, F. Piras, P. Cugia, P. Cieszczyk, F. Tocco, C. M. Calo
Summary: The study investigated the influence of MCT1 T1470A polymorphism on repeated sprint ability and lactate accumulation in elite Italian male football players. The results showed that carriers of the major A-allele (Glu-490) in the dominant model exhibited significantly lower sprint times in the RSA test.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Cell Biology
Julia Brenmoehl, Elli Brosig, Nares Trakooljul, Christina Walz, Daniela Ohde, Antonia Noce, Michael Walz, Martina Langhammer, Stefan Petkov, Monika Roentgen, Steffen Maak, Christina E. E. Galuska, Beate Fuchs, Bjoern Kuhla, Siriluck Ponsuksili, Klaus Wimmers, Andreas Hoeflich
Summary: This study investigated the contribution of non-mitochondrial and mitochondrial metabolic pathways in contracting muscles during repeated training. The results showed that marathon mice displayed increased glucose and fatty acid oxidation, reduced lactate dehydrogenase activity, and inhibited lactate formation compared to trained control mice. This suggests that marathon mice have enhanced metabolic flexibility towards lipid catabolism regulated by lactate dehydrogenase.
Article
Geriatrics & Gerontology
Shu Yang, Guangyan Yang, Xinyu Wang, Lixing Li, Yanchun Li, Jiaqing Xiang, Lin Kang, Zhen Liang
Summary: This study revealed that miR-92b regulates glycogen and lactate metabolism in skeletal muscle through pathways involving miR-92b-3p/UGP2/glycogen synthesis and miR-92b-5p/MCT4/lactate extrusion.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Physiology
Nobukazu Kasai, Fumiya Tanji, Aya Ishibashi, Hayato Ohnuma, Hideyuki Takahashi, Kazushige Goto, Yasuhiro Suzuki
Summary: A single session of sprint interval training in hypoxia led to a significant decrease in muscle glycogen content without affecting power output. The relative change in muscle glycogen content was significantly higher in the hypoxia trial compared to the normoxia trial.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Bingyang Liu, Yang Gou, Takamasa Tsuzuki, Takako Yamada, Tetsuo Iida, Sixian Wang, Ryoichi Banno, Yukiyasu Toyoda, Teruhiko Koike
Summary: This study found that administration of d-Allulose improved aerobic performance and recovery from exhaustion in mice. It increased maximal aerobic speed, decreased blood lactate levels, and increased liver glycogen levels. It also improved insulin sensitivity. Overall, d-Allulose administration had similar effects to exercise training.
Article
Neurosciences
Carlos Rodriguez-Lopez, Alfredo Santalla, Pedro. L. Valenzuela, Alberto Real-Martinez, Monica Villarreal-Salazar, Irene Rodriguez-Gomez, Tomas Pinos, Ignacio Ara, Alejandro Lucia
Summary: This study compared the fat oxidation rate between patients with McArdle disease and healthy controls. The results showed that despite having a lower peak oxygen uptake, McArdle patients had a higher fat oxidation rate. This may be a compensatory adaptation due to the complete blockade of muscle glycogen metabolism in these patients.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Rehabilitation
J. A. Stewart, E. K. Merritt, D. E. Lidstone, J. M. McBride, K. A. Zwetsloot
Summary: The purpose of this study was to determine the impact of performing cycling before running in collegiate triathletes. It was found that mechanical efficiency of running was decreased and anaerobic energy expenditure was increased when a 40-km bout of cycling was performed immediately before running.
BMC SPORTS SCIENCE MEDICINE AND REHABILITATION
(2022)
Article
Sport Sciences
David Varillas-Delgado, Esther Morencos, Jorge Gutierrez-Hellin, Millan Aguilar-Navarro, Antonio Maestro, Teresa Perucho, Juan Del Coso
Summary: The influence of the rs8111989 polymorphism in the muscle-specific creatine kinase gene ( CKM ) on injury incidence is unknown. This study found that the CKM polymorphism did not affect injury incidence in high-performance football players. However, players with the GA genotype were more prone to severe injuries and muscle tears.
INTERNATIONAL JOURNAL OF SPORTS MEDICINE
(2023)
Article
Physiology
Rune Hokken, Simon Laugesen, Per Aagaard, Charlotte Suetta, Ulrik Frandsen, Niels Ortenblad, Joachim Nielsen
Summary: The study found that heavy weightlifting exercise results in substantial glycogen utilization from all three subcellular localizations in type 2 fibers, while primarily depleting intermyofibrillar glycogen stores in type 1 fibers. Therefore, a better understanding of the impact of resistance training on myocellular metabolism and performance requires focusing on compartmentalized glycogen utilization.
Article
Biochemistry & Molecular Biology
Yumiko Takahashi, Juli Sarkar, Jumpei Yamada, Yutaka Matsunaga, Yudai Nonaka, Mai Banjo, Ryo Sakaguchi, Terunaga Shinya, Hideo Hatta
Summary: The study compared the effects of level running and downhill running on post-exercise muscle glycogen repletion in mice, finding that the level running group showed significant glycogen supercompensation in muscles at 2 days post-exercise, while the downhill running group did not. The findings suggest that muscle glycogen repletion after exercise may be partly influenced by plasma insulin and skeletal muscle HK2 protein levels.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Physiology
Natalie R. Janzen, Jamie Whitfield, Lisa Murray-Segal, Bruce E. Kemp, John A. Hawley, Nolan J. Hoffman
Summary: Disrupting AMPK-glycogen interaction reduces maximal exercise capacity and skeletal muscle AMPK alpha and beta 2 content, and increases glycogen utilization.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Sport Sciences
Alex Pedersen, Morten B. Randers, Live S. Luteberget, Merete Moller
Summary: This study validates the use of session rating of perceived exertion (sRPE) as a measure of training load in youth team handball players. The results show strong correlations between sRPE load and heart rate expressed as Edwards Summated Heart Rate Zones (SHRZ) and PlayerLoad. sRPE load was also able to differentiate between high and low training load categories.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Youssif Merhi, Pablo F. Betancur, Teresa S. Ripolles, Charlotte Suetta, Morten R. Brage-Andersen, Sofie K. Hansen, Anders Frydenlund, Jens Vinge Nygaard, Peter H. Mikkelsen, Pablo P. Boix, Shweta Agarwala
Summary: Muscle atrophy is a common problem caused by immobilization and critical illness, leading to rehabilitation difficulties and increased mortality. This study presents a solution for preserving muscle mass through the use of a customized biocompatible neuromuscular electrical stimulation (NMES) device. The integration of dry and biocompatible electrodes into a compressive stocking textile was demonstrated, resulting in extended usage without skin irritation. Electrochemical analysis showed improved performance of the printed electrodes compared to commercial ones, and promising results were obtained in a hospital setting for muscle atrophy evaluation.
Article
Oncology
Troels Gammeltoft Dolin, Marta Kramer Mikkelsen, Henrik Loft Jakobsen, Anders Vinther, Bo Zerahn, Dorte Lisbet Nielsen, Julia Sidenius Johansen, Cecilia Margareta Lund, Charlotte Suetta
Summary: This study aimed to investigate the prevalence of preoperative sarcopenia and cachexia in older vulnerable patients with localized colorectal cancer. The results showed that 28% of patients had low muscle strength, 13% met the criteria for sarcopenia, and 33% had low muscle mass. There was an association between low muscle mass and cachexia, but no association between sarcopenia and cachexia.
JOURNAL OF GERIATRIC ONCOLOGY
(2023)
Article
Sport Sciences
Ivone Carneiro, Peter Krustrup, Carlo Castagna, Magni Mohr, Jose Magalhaes, Rita Pereira, Rute Santos, Sandra Martins, Joao Tiago Guimaraes, Eduardo Coelho, Susana Povoas
Summary: This study aimed to examine the dose-response of a recreational team handball exercise-based programme on cardiometabolic health and physical fitness in inactive middle-aged-to-elderly males without TH experience. The results showed that performing three 60-minute team handball exercise sessions per week can improve aerobic performance in middle-aged-to-elderly men, and it is more effective than training with a lower weekly frequency.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Sport Sciences
Zhen Li, Peter Krustrup, Morten Bredsgaard Randers, Bo Xu, Weixin Yang, Zhixiong Huang, Lijuan Mao
Summary: The aim of this study was to investigate the positive impact of the 11 for Health programme on the physical fitness of Chinese primary school students. The results showed that the experimental group, who participated in small-sided football sessions, exhibited greater improvements in systolic blood pressure, postural balance, standing long jump, 30-metre sprint, and Yo-Yo IR1C running performance compared to the control group. Additionally, both groups experienced an increase in physical activity enjoyment during the intervention period.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Sport Sciences
Rita Pereira, Peter Krustrup, Carlo Castagna, Eduardo Coelho, Eva Wulff Helge, Niklas Rye Jorgensen, Carolina Vila-Cha, Sandra Martins, Joao Tiago Guimaraes, Jose Magalhaes, Susana Povoas
Summary: A multicomponent exercise training protocol (recreational team handball training) has long-term positive effects on global health status in inactive postmenopausal women. After 36 weeks of training, participants in the exercise group showed improvements in cardiovascular, bone, metabolic health, body composition, and physical fitness markers.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Neurosciences
Javier Botella, Camilla T. Schytz, Thomas F. Pehrson, Rune Hokken, Simon Laugesen, Per Aagaard, Charlotte Suetta, Britt Christensen, Niels Ortenblad, Joachim Nielsen
Summary: This study investigated the mitochondrial structural characteristics in skeletal muscle of strength athletes compared to untrained controls. The results showed that strength athletes had increased mitochondrial cristae density, decreased mitochondrial size, and increased surface-to-volume ratio in their mitochondrial pool, despite similar mitochondrial volume density. In addition, resistance exercise led to mild mitochondrial stress but did not increase the number of damaged mitochondria. Moreover, the study found that acute resistance exercise increased the expression of markers of mitochondrial biogenesis, fission, and mitochondrial unfolded protein responses (UPRmt), and strength-trained individuals showed an enrichment of the UPRmt in their basal transcriptome. These findings suggest that strength athletes have a unique mitochondrial remodeling that minimizes the space required for mitochondria.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Multidisciplinary Sciences
Susana Povoas, Peter Krustrup, Carlo Castagna
Summary: The criterion validity and sensitivity of heart-rate recovery (HRRec) in profiling cardiorespiratory fitness were examined in male recreational football players. The results showed that HRRec is not a reliable indicator of cardiorespiratory fitness and training status in this population.
Article
Multidisciplinary Sciences
Ivone Carneiro, Peter Krustrup, Carlo Castagna, Rita Pereira, Susana Povoas
Summary: This study examined the physical and physiological demands and perceived experience of recreational team handball for middle-aged/elderly men and women, comparing same- vs. mixed-gender 6v6 game formats. The results showed that mixed-gender matches are more demanding for women in terms of heart rate and physical exertion, while same-gender matches require higher cardiovascular and activity profile demands for men. However, team handball is a high-intensity and motivating exercise mode for both genders, regardless of the gender game format.
Article
Sport Sciences
May-Britt Skoradal, Maria Hammer Olsen, Mads Madsen, Malte Nejst Larsen, Magni Mohr, Peter Krustrup
Summary: This study investigated the popularity and effects of the 11 for Health program on well-being and health knowledge for 10-12-year-old Faroese children. The results showed that the program improved physical well-being, social support, and health knowledge. The program was also highly rated by the children.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Physiology
Morten B. Randers, Marie Hagman, Jesper F. Christensen, Susana Povoas, Jens Jung Nielsen, Peter Krustrup
Summary: The purpose of this study was to compare the effects of street football training and grass football training on the health and exercise performance of young men. The results showed that street football training improved submaximal exercise capacity, while grass football training had positive effects on submaximal exercise capacity and cardiorespiratory fitness.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Sport Sciences
Ivone Carneiro, Peter Krustrup, Carlo Castagna, Rita Pereira, Niklas Rye Jorgensen, Eduardo Coelho, Susana Povoas
Summary: The study aimed to analyze the effects of different weekly exercise volumes on the bone health, body composition, and physical fitness of inactive middle-to-older-aged males. The results showed that the intervention groups that performed 2-3 weekly training sessions had the greatest improvements in bone health, body composition, and physical fitness.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Article
Sport Sciences
Hallur Thorsteinsson, Jeppe F. Vigh-Larsen, Jeppe Panduro, Bjorn Fristrup, Daniel Zornow Kruse, Lasse Gliemann, Marte Egeland, Jens L. Olesen, Per Aagaard, Morten B. Randers, Peter Krustrup, Lars Nybo, Kristian Overgaard, Magni Mohr
Summary: The present study aimed to evaluate the acute decrements and subsequent recovery of skeletal muscle glycogen levels, muscle function, and repeated-sprint ability following ice hockey game-play. The results showed that muscle glycogen content and muscle function decreased significantly after the game, but the impact on repeated-sprint ability was minimal and fully recovered within 1-2 days postgame.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)