Article
Physiology
Loic Lebesque, Gil Scaglioni, Alain Martin
Summary: This study aims to explore the effects of different torque-time integrals (TTI) on neuromuscular fatigability and highlights the importance of using sustained maximal voluntary contraction (MVC1-MIN) to assess neuromuscular fatigability.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Sport Sciences
Giuseppe Coratella, Emiliano Ce, Christian Doria, Marta Borrelli, Nicholas Toninelli, Susanna Rampichini, Eloisa Limonta, Stefano Longo, Fabio Esposito
Summary: Using the mechanomyographic (MMG) signal to detect voluntary activation (VA(MMG)), the study examined the effects of neural and mechanical factors on force output after passive stretching. The results showed that passive stretching increased dorsiflexion range but decreased joint passive stiffness, maximum voluntary contraction, VA, and VA(MMG).
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Sport Sciences
Manuel Dote-Montero, Ignacio Pelayo-Tejo, Pablo Molina-Garcia, Abraham Carle-Calo, Amador Garcia-Ramos, Luis J. Chirosa-Rios, Ignacio J. Chirosa-Rios, Francisco J. Amaro-Gahete
Summary: The most effective potentiation protocol to increase maximum strength is currently unknown. This study investigated the effects of post-tetanic potentiation (PTP) induced by whole-body electrostimulation (WB-EMS) and post-activation potentiation (PAP) induced by voluntary maximum isometric contractions on maximum isometric strength. The results showed that neither WB-EMS nor the combination of WB-EMS and PAP produced a significant increase in maximum isometric strength compared to the control and PAP alone.
Review
Sport Sciences
Stacey Woods, Caragh O'mahoney, James Maynard, Raffy Dotan, Gershon Tenenbaum, Edson Filho, Bareket Falk
Summary: Compared with adults, children activate their motor-unit pool less. Moreover, the degree of volitional muscle activation increase with age may be influenced by the muscle examined (upper vs lower extremity). However, more research is needed to elucidate the influence of this possible factor, as the current review contains limited data from upper body muscles. The developmental mechanism responsible for children's lower volitional muscle activation requires further research.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Physiology
Jan-Frieder Harmsen, Christopher Latella, Ricardo Mesquita, Alessandro Fasse, Moritz Schumann, Michael Behringer, Janet Taylor, Kazunori Nosaka
Summary: This study found that the acute effects of muscle cramping induced by maximal voluntary isometric contractions (MVIC) and neuromuscular electrical stimulation (NMES) on the amplitude of Hoffmann reflexes (H-reflex) and compound muscle action potentials (M-wave) were inconsistent. While MVIC-induced muscle cramps reduced H-reflex amplitude, muscle stretch to end cramping was a potential contributing factor, whereas NMES may potentiate H-reflexes and obscure cramp-related changes.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Physiology
Zengyuan Lin, Anthony J. J. Blazevich, Chris R. R. Abbiss, Jodie Cochrane Wilkie, Kazunori Nosaka
Summary: This study investigated muscle damage and neuromuscular function changes after simulated badminton singles matches. The results showed that knee extensor MVC torque and other measures decreased immediately after the match, but recovered within 24 hours. The number of lunges performed in a match was correlated with the decrease in MVC torque. Muscle soreness was more severe in the dominant leg compared to the non-dominant leg.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Sport Sciences
Cassio Ruas, Christopher Latella, Janet L. Taylor, G. Gregory Haff, Kazunori Nosaka
Summary: This study aimed to investigate whether the changes in maximal voluntary isometric contraction (MVIC) strength 1 to 3 days after unaccustomed eccentric exercise (ECC) were correlated with changes in central and peripheral neuromuscular parameters immediately post-ECC. The results indicated that the changes in rate of force development (RFD) and motor-evoked potentials (MEP)/maximal M-wave (M-MAX) immediately post-ECC were associated with the magnitude of decrease in MVIC strength at 1 to 3 days post-ECC. However, these markers were not sensitive for the practical detection of muscle damage based on individual data.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Physiology
James L. Nuzzo, David S. Kennedy, Harrison T. Finn, Janet L. Taylor
Summary: The contemporary procedure for assessing voluntary activation of the knee extensor muscles with TMS is invalid, but a modified procedure may improve validity in select individuals meeting rigorous eligibility criteria.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Przemyslaw Domaszewski, Pawel Pakosz, Mariusz Konieczny, Dawid Baczkowicz, Ewa Sadowska-Krepa
Summary: The study confirmed the effectiveness of caffeine supplementation in improving muscle activation time during sports. It demonstrated that a dose of 9 mg/kg of caffeine can significantly reduce contraction time and muscle displacement in professional athletes, who regularly consume caffeine-rich products.
Article
Sport Sciences
Haiko Bruno Zimmermann, Filipe Estacio Costa, Raphael Sakugawa, Brian MacIntosh, Fernando Diefenthaeler, Juliano Dal Pupo
Summary: The study found that plyometric conditioning activity can increase muscle peak torque and rate of torque development, consistent with postactivation potentiation (PAP); however, this training activity does not improve the voluntary force response of the muscles. This suggests that more research is needed to explore how to most effectively increase muscle isometric peak torque.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2022)
Article
Physiology
Emiliano Ce, Giuseppe Coratella, Christian Doria, Marta Borrelli, Susanna Rampichini, Eloisa Limonta, Stefano Longo, Fabio Esposito
Summary: This study proposes a novel approach based on MMG signal analysis to detect voluntary activation (VA) of the synergistic superficial heads of the quadriceps muscle. The results show that VA(MMG) can be effectively used to assess VA and provide additional information when multiple synergistic muscle heads are involved in fatiguing exercises.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Neurosciences
Thibault Roumengous, Bhushan Thakkar, Carrie L. L. Peterson
Summary: Spinal cord injuries (SCI) can lead to changes in the nervous system, including cortical changes. The measurement of voluntary cortical/subcortical drive to muscle using transcranial magnetic stimulation (VA(TMS)) is limited by technical challenges. This study investigated the effect of the motor evoked potential (MEP) ratio on VA(TMS) in individuals with tetraplegia and found that MEP ratio did not affect voluntary activation.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Physiology
Stefanos Volianitis, Peter Rasmussen, Nicolas C. Petersen, Niels H. Secher
Summary: This study evaluates the effect of hyperoxia on cerebral oxygenation and neuromuscular fatigue mechanisms of the elbow flexor muscles following ergometer rowing. The results indicate that hyperoxia can increase cerebral oxygenation and attenuate muscle fatigue after rowing, suggesting that this effect is peripheral rather than centrally mediated.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Takeshi Sugimoto, Tomohiro Nakamura, Sho Yokoyama, Toshia Fujisato, Satoshi Konishi, Takeshi Hashimoto
Summary: This study investigated the effects of electrical pulse stimulation (EPS)-evoked muscle contraction on irisin and CTSB secretion in 3D-engineered muscle (3D-EM). The results showed a significant increase in irisin secretion following EPS, while no significant difference was observed in CTSB secretion between the two groups. Irisin may be a contractile muscle-derived myokine, but CTSB is not secreted by EPS-evoked muscle contractile stimulation in 3D-EM.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Physiology
Kazutaka Ota, Kazushige Sasaki
Summary: This study aimed to investigate the influence of temperature on post-activation twitch potentiation. The findings showed that the magnitude of twitch potentiation varied with different temperature conditions, but temperature did not affect the twitch potentiation following submaximal contractions.
PHYSIOLOGICAL REPORTS
(2023)
Review
Pharmacology & Pharmacy
Jules A. A. C. Heuberger, April Henning, Adam F. Cohen, Bengt Kayser
Summary: The establishment of WADA has brought about changes in doping behavior and prevention over the past 22 years. However, deficiencies and limitations in the system have caused harm to sports, athletes, and society. This article advocates for more scientific evidence, improved governance, and enhanced education to address these issues and promote positive reform among stakeholders.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Johannes Burtscher, Gregoire P. Millet, Nicolas Place, Bengt Kayser, Nadege Zanou
Summary: Regular exercise has pronounced health benefits, with enhanced mitochondrial functions in skeletal muscle playing a central role in exercise-induced adaptations. Along with muscle, regular exercise also benefits the brain and is crucial in protecting against neurodegenerative diseases. Mitochondria seem to be central players in the communication routes from muscle to the brain induced by exercise.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Multidisciplinary Sciences
Pirkka-Pekka Laurila, Peiling Luan, Martin Wohlwend, Nadege Zanou, Barbara Crisol, Tanes Imamura de Lima, Ludger J. E. Goeminne, Hector Gallart-Ayala, Minho Shong, Julijana Ivanisevic, Nicolas Place, Johan Auwerx
Summary: Inhibition of sphingolipid synthesis, targeting multiple pathogenic pathways, shows promise as a potential treatment for muscular dystrophies.
Article
Medicine, General & Internal
Vanessa Wellauer, Julia F. Item, Mario Bizzini, Nicola A. Maffiuletti
Summary: This study compared the effectiveness of a home-based NMES program to a sham-NMES program in patients following ACL reconstruction. The results showed that a 6-week home-based NMES program applied to the quadriceps of the nonoperative side prevented knee extensor muscle weakness 6 months after surgery.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Sport Sciences
Victor R. A. Cossich, Ubirata F. Gavilao, Rodrigo A. Goes, Jamila A. Perini, Conrado T. Laett, Nicola A. Maffiuletti
Summary: This study compared the inter-limb asymmetry in maximal and explosive knee extensor strength in professional soccer players and found that explosive knee extensor strength exhibited larger inter-limb asymmetry and better relations with self-reported knee function.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Editorial Material
Physiology
Ramona Ritzmann, Alessandro Del Vecchio, Stephane Baudry, Nicolas Place, Albert Gollhofer, Marco Narici, Christoph Centner
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Sport Sciences
Tiffany Astolfi, Fabienne Crettaz Von Roten, Bengt Kayser, Martial Saugy, Raphael Faiss
Summary: This study aimed to investigate the influence of regular breath-hold training on hematological variables. The results showed that there were significant variations in hematological values over time due to both breath-hold training and seasonal effects. However, compared to an active lifestyle, breath-hold training did not induce significant variations in hematological variables over one year.
JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
(2022)
Article
Cell Biology
Michael R. Deyhle, Chandler S. Callaway, Daria Neyroud, Andrew C. D'Lugos, Sarah M. Judge, Andrew R. Judge
Summary: In this study, the researchers found that anti-Ly6G treatment reduced cancer-induced skeletal muscle wasting in a pancreatic cancer model, possibly by decreasing the number of Ly6G+ cells in the tumor and skeletal muscle.
Article
Biology
Chris Donnelly, Timothee Popesco, Julie Rosse, Bengt Kayser, Nicola A. Maffiuletti, Nicolas Place
Summary: This study compared contralateral facilitation of plantar flexor strength during rest and different types of NMES stimulation. The results showed that neither conventional nor wide-pulse high-frequency NMES induced any contralateral facilitation of maximal voluntary strength.
Article
Physiology
Loic Espeit, Thomas Lapole, Guillaume Y. Millet, Vianney Rozand, Nicola A. Maffiuletti
Summary: The study compared the maximal evocable torque (MET) between conventional and wide-pulse neuromuscular electrical stimulation (NMES) at two different frequencies. The results showed that wide-pulse protocols led to greater MET and lower maximal tolerable current intensity compared to conventional NMES.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Physiology
Javier Rodriguez-Falces, Armando Malanda, Javier Navallas, Nicolas Place
Summary: This study aimed to experimentally assess the changes in the compound muscle action potential (M-wave) caused by brief voluntary and stimulated isometric contractions. Two methods of inducing muscle shortening were used under isometric condition, and the amplitude and duration of the M-wave phases were measured. The results showed that muscle shortening led to a decrease in the amplitude of the first phase and an increase in the amplitude of the second phase of the M-wave.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Sport Sciences
Darias Holgado, Leo Jolidon, Guillermo Borragan, Daniel Sanabria, Nicolas Place
Summary: A study analyzing neurophysiological and physical responses found that individualized mental fatigue tasks do not adversely affect neuromuscular function or physical exercise.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Rehabilitation
Mario Bizzini, Gianluca Schaub, Enea Ferrari, Samara Monn, Michael Leunig, Nicola C. Casartelli, Nicola A. Maffiuletti
Summary: This study aimed to examine hip muscle strength deficits in patients with femoroacetabular impingent syndrome (FAIS), with a special focus on potential sex and comparison-related differences. The results showed that women had 14-18% weaker hip muscle strength compared to men, while FAIS patients had 16-19% weaker hip muscle strength compared to healthy controls and 24-30% weaker hip muscle strength compared to athletes. Among FAIS patients, the involved hip abductors were 8.5% weaker than the uninvolved ones, with no inter-limb asymmetry observed for the other hip muscles.
PHYSICAL THERAPY IN SPORT
(2023)
Article
Cell Biology
Pirkka-Pekka Laurila, Martin Wohlwend, Tanes Imamura de Lima, Peiling Luan, Sebastien Herzig, Nadege Zanou, Barbara Crisol, Maroun Bou-Sleiman, Eleonora Porcu, Hector Gallart-Ayala, Michal K. Handzlik, Qi Wang, Suresh Jain, Davide D'Amico, Minna Salonen, Christian M. Metallo, Zoltan Kutalik, Thomas O. Eichmann, Nicolas Place, Julijana Ivanisevic, Jari Lahti, Johan G. Eriksson, Johan Auwerx
Summary: Age-related muscle dysfunction and sarcopenia can be prevented by inhibiting sphingolipid synthesis, which enhances muscle mass, strength, and exercise capacity. Inhibition of sphingolipid synthesis promotes myogenic potential and protein synthesis.