Article
Neurosciences
Brenda Jeng, Katie L. J. Cederberg, Byron Lai, Jeffer E. Sasaki, Marcas M. Bamman, Robert W. Motl
Summary: The study showed a strong association between wrist-based activity counts and energy expenditure for both persons with PD and controls, with significantly different cut-points for quantifying time spent in MVPA between the two groups.
Article
Chemistry, Analytical
Sunku Kwon, Youngwon Kim, Yang Bai, Ryan D. Burns, Timothy A. Brusseau, Wonwoo Byun
Summary: This study evaluated the concurrent validity of the Apple Watch 3 in estimating moderate-to-vigorous physical activity (MVPA) time and active energy expenditure (AEE) in school-aged children under simulated and free-living conditions. The Apple Watch provided comparable estimates for MVPA time and AEE during the simulated free-living condition, but had relatively large variability in estimating AEE in children. The Apple Watch was statistically equivalent to the K5 within a certain range for MVPA time and AEE estimates.
Article
Pediatrics
Pilar Ferrer-Santos, Iris Iglesia, Borja Muniz-Pardos, Maria Luisa Miguel-Berges, Paloma Flores-Barrantes, Luis A. Moreno, Gerardo Rodriguez-Martinez
Summary: Most studies lack early stage information and accurate methods when analyzing the impact of moderate to vigorous physical activity (MVPA) on children's health. The CALINA study in Spain investigated the association between physical activity and body composition in children using objective methods and WHO recommendations, finding that active children had lower body fat percentages. Boys were more likely to meet the WHO PA recommendations compared to girls, and MVPA was associated with lower body fat in both genders. Further research is needed to determine the MVPA thresholds that benefit boys and girls across all body composition components.
Article
Sport Sciences
Einar Ylvisaker, Ada Kristine Ofrim Nilsen, Kjersti Johannessen, Eivind Aadland
Summary: This study aimed to determine the associations between weather and playground surface conditions and time spent outdoors and in moderate-to-vigorous physical activity (MVPA) in preschool children aged 3-6 years in Norway. The findings suggest that temperature and playground surface conditions were associated with children's levels of physical activity.
JOURNAL OF SPORTS SCIENCES
(2022)
Review
Neurosciences
Yanlin Wu, Jennifer L. Petterson, Nick W. Bray, Derek S. Kimmerly, Myles W. O'Brien
Summary: Research indicates that activPAL has high accuracy in measuring stepping activity, but lower accuracy in identifying physical activity intensity. Some studies suggest that activPAL tends to underestimate vigorous-intensity activity.
Article
Hospitality, Leisure, Sport & Tourism
Jonna Nilsson, Maria Ekblom, Martin Lovden
Summary: It has been found in a cross-sectional study of 115 healthy older adults that moderate-to-vigorous physical activity is positively associated with working memory and cardiorespiratory fitness is positively associated with episodic memory. These findings provide a foundation for further research on the relationship between cognition and physical activity in old age.
PSYCHOLOGY OF SPORT AND EXERCISE
(2022)
Article
Public, Environmental & Occupational Health
Chloe Bedard, Sara King-Dowling, Joyce Obeid, Brian W. Timmons, Mark A. Ferro
Summary: This study found that children with chronic physical illness and multimorbidity are insufficiently active, and their physical activity is correlated with factors such as age and physical health-related quality of life.
HEALTH EDUCATION & BEHAVIOR
(2022)
Article
Public, Environmental & Occupational Health
Markus Gerber, Serge A. Ayekoe, Johanna Beckmann, Bassirou Bonfoh, Kouadio Benal Kouassi, Bomey Clement Gba, Sylvain G. Traore, Jean T. Coulibaly, Dao Daouda, Rosa du Randt, Marceline F. Finda, Elihaika G. Minja, Stefanie Gall, Getrud J. Mollel, Christin Lang, Kurt Z. Long, Honorati Masanja, Ivan Mueller, Siphesihle Nqweniso, Fredros O. Okumu, Nicole Probst-Hensch, Uwe Puhse, Peter Steinmann, Cheryl Walter, Juerg Utzinger
Summary: The study compared physical activity and cardiorespiratory fitness levels among primary schoolchildren in different African countries, finding that higher levels of physical activity were associated with better cardiorespiratory fitness. Urbanization may increase the risk of insufficient physical activity among primary school girls.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Sport Sciences
Xinzheng Sun, Zhichao Wang, Xiangyin Fu, Changtao Zhao, Fatao Wang, Hui He
Summary: The validity of energy expenditure measurements taken by the Apple Watch 6 and Polar A370 was assessed in this study. The results showed that both devices provide similar levels of accuracy during treadmill and ground running exercise, but still have room for improvement.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2023)
Article
Public, Environmental & Occupational Health
Sandra Silva-Santos, Amanda Santos, Clarice Martins, Michael Duncan, Maria Joao Lagoa, Susana Vale, Jorge Mota
Summary: The study found a positive association between increased motor competence and moderate to vigorous physical activity, leading to decreased BMI in preschoolers. Preschoolers with higher levels of motor competence were more likely to spend more time in moderate to vigorous physical activity.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Chelsea L. Kracht, Sai S. Pochana, Amanda E. Staiano
Summary: This study used a longitudinal approach to examine the bidirectional relationship between moderate to vigorous physical activity (MVPA), sedentary behavior (SB), and depressive symptomatology in adolescents. The results showed that adolescents with less time spent in SB had lower depressive symptomatology at follow-up. Therefore, limiting time spent in SB in adolescence may improve future mental health.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2023)
Article
Psychology, Multidisciplinary
Juan L. Nunez, Jaime Leon, Alfonso Valero-Valenzuela, Luis Conte, Juan A. Moreno-Murcia, Elisa Huescar
Summary: This study found that physical self-concept did not directly influence MVPA in adolescents, while needs satisfaction and autonomous motivation were positively related to MVPA. Physical self-concept indirectly influenced adolescents' physical activity levels through needs satisfaction and autonomous motivation.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Yaru Hao, Rizal Razman
Summary: This study investigated the MVPA levels of children with intellectual disability (ID) during PE classes in China and found that they spent only 22.88% of the class time in MVPA. The MVPA levels varied by grade and gender, with fourth-grade children spending more time in MVPA and boys outperforming girls. The findings suggest the need for educators to reevaluate the PE curriculum and consider grade and gender when devising new content.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Yasmin Mossavar-Rahmani, Juan Lin, Stephanie Pan, Rebecca J. Song, Xiaonan Xue, Nicole L. Spartano, Vanessa Xanthakis, Daniela Sotres-Alvarez, David X. Marquez, Martha Daviglus, Jordan A. Carlson, Humberto Parada Jr, Kelly R. Evenson, Ana C. Talavera, Marc Gellman, Krista M. Perreira, Linda C. Gallo, Ramachandran S. Vasan, Robert C. Kaplan
Summary: This study examined the correlates of changes in physical activity in Hispanic/Latino adults and found that age, gender, education, and income were associated with changes in physical activity. The findings can inform targeted interventions for promoting physical activity.
Article
Multidisciplinary Sciences
Brenda Kitilya, George PrayGod, Robert Peck, John Changalucha, Kidola Jeremiah, Bazil Baltazar Kavishe, Henrik Friis, Suzanne Filteau, Daniel Faurholt-Jepsen, Rikke Krogh-Madsen, Soren Brage, Mette F. Olsen
Summary: In Mwanza, Tanzania, HIV-infected individuals have lower levels of physical activity and capacity compared to HIV-uninfected individuals. The correlates of physical activity and capacity differ between HIV-infected and HIV-uninfected individuals.
Article
Sport Sciences
Annie M. Skinner, Dimitris Vlachopoulos, Alan R. Barker, Sarah A. Moore, Alex Rowlands, Sonja Soininen, Eero A. Haapala, Juuso Vaisto, Kate Westgate, Soren Brage, Timo A. Lakka
Summary: The study aimed to assess the associations of physical activity (PA) volume, PA intensity distribution, and moderate-to-vigorous PA (MVPA) with bone mineral content, lean mass, and fat mass in children. The results showed that PA volume was positively associated with bone mineral content in both females and males, and positively associated with lean mass (males) or negatively associated with fat mass (males). PA intensity was negatively associated with bone mineral content in males. MVPA was positively associated with lean mass and negatively associated with fat mass in both females and males.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Endocrinology & Metabolism
Tessa Strain, Paddy C. Dempsey, Katrien Wijndaele, Stephen J. Sharp, Nicola Kerrison, Tomas I. Gonzales, Chunxiao Li, Eleanor Wheeler, Claudia Langenberg, Soren Brage, Nick Wareham
Summary: The research found a linear relationship between physical activity energy expenditure (PAEE) and incident type 2 diabetes (T2D), with higher levels of PAEE associated with lower odds of T2D. This association was stronger in men, and weaker in individuals with obesity and higher genetic susceptibility to obesity. For a given level of PAEE, engaging in more moderate-to-vigorous activity was associated with lower odds of T2D.
Article
Sport Sciences
Tomas I. Gonzales, Kate Westgate, Stefanie Hollidge, Tim Lindsay, Katrien Wijndaele, Nita G. Forouhi, Simon Griffin, Nick Wareham, Soren Brage
Summary: This study examined the relationship between cardiorespiratory fitness and population subgroups and seasonal trends in a population-based cohort of UK adults. The findings showed that older generations are comparatively fitter than younger generations, but the decline in fitness with age is less steep than anticipated. Physical activity energy expenditure and BMI were found to be stronger determinants of cardiorespiratory fitness than other characteristics, emphasizing the importance of modifiable physical activity behaviors in public health interventions.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Biotechnology & Applied Microbiology
Rosa Lundbye Allesoe, Agnete Troen Lundgaard, Ricardo Hernandez Medina, Alejandro Aguayo-Orozco, Joachim Johansen, Jakob Nybo Nissen, Caroline Brorsson, Gianluca Mazzoni, Lili Niu, Jorge Hernansanz Biel, Valentas Brasas, Henry Webel, Michael Eriksen Benros, Anders Gorm Pedersen, Piotr Jaroslaw Chmura, Ulrik Plesner Jacobsen, Andrea Mari, Robert Koivula, Anubha Mahajan, Ana Vinuela, Juan Fernandez Tajes, Sapna Sharma, Mark Haid, Mun-Gwan Hong, Petra B. Musholt, Federico De Masi, Josef Vogt, Helle Krogh Pedersen, Valborg Gudmundsdottir, Angus Jones, Gwen Kennedy, Jimmy Bell, E. Louise Thomas, Gary Frost, Henrik Thomsen, Elizaveta Hansen, Tue Haldor Hansen, Henrik Vestergaard, Mirthe Muilwijk, Marieke T. Blom, Leen M. T. Hart, Francois Pattou, Violeta Raverdy, Soren Brage, Tarja Kokkola, Alison Heggie, Donna McEvoy, Miranda Mourby, Jane Kaye, Andrew Hattersley, Timothy McDonald, Martin Ridderstrale, Mark Walker, Ian Forgie, Giuseppe N. Giordano, Imre Pavo, Hartmut Ruetten, Oluf Pedersen, Torben Hansen, Emmanouil Dermitzakis, Paul W. Franks, Jochen M. Schwenk, Jerzy Adamski, Mark McCarthy, Ewan Pearson, Karina Banasik, Simon Rasmussen, Soren Brunak
Summary: The application of multiple omics technologies in biomedical cohorts can reveal patient-level disease characteristics and individualized response to treatment. We developed a deep-learning-based framework, MOVE, to integrate and analyze multi-omics data from a cohort of newly diagnosed type 2 diabetes patients. By using in silico perturbations, we identified drug-omics associations in the multi-modal datasets with higher sensitivity than univariate statistical tests.
NATURE BIOTECHNOLOGY
(2023)
Article
Anthropology
Dirk L. Christensen, Kate Westgate, Lewis Griffiths, Joseph Sironga, Venance P. Maro, Jorn W. Helge, Steen Larsen, Ib C. Bygbjerg, Kaushik L. Ramaiya, Jorgen Jensen, Soren Brage
Summary: This study aimed to objectively quantify the metabolic intensity of traditional jumping-dance activity performed by Maasai men and assess its associations with habitual physical activity and cardiorespiratory fitness. The findings showed that the intensity of jumping-dance activity was moderate, but on average seven times higher than habitual physical activity.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2023)
Review
Sport Sciences
Leandro Garcia, Matthew Pearce, Ali Abbas, Alexander Mok, Tessa Strain, Sara Ali, Alessio Crippa, Paddy C. Dempsey, Rajna Golubic, Paul Kelly, Yvonne Laird, Eoin McNamara, Samuel Moore, Thiago Herick de Sa, Andrea D. Smith, Katrien Wijndaele, James Woodcock, Soren Brage
Summary: This study aims to estimate the dose-response associations between non-occupational physical activity and chronic disease outcomes and mortality. The results show that even small increases in non-occupational physical activity can significantly reduce the risk of various diseases and mortality compared to being inactive.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Health Care Sciences & Services
Dharani Yerrakalva, Samantha Hajna, Marc Suhrcke, Katrien Wijndaele, Kate Westgate, Kay-Tee Khaw, Nick Wareham, Soren Brage, Simon Griffin
Summary: This study examines the associations between changes in objectively-measured physical behaviours and follow-up quality of life in older adults. The results show that higher levels of physical activity and lower levels of sedentary time are associated with higher quality of life. Therefore, this relationship should be considered in future cost effectiveness analyses to promote more activity interventions.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2023)
Correction
Biotechnology & Applied Microbiology
Rosa Lundbye Allesoe, Agnete Troen Lundgaard, Ricardo Hernandez Medina, Alejandro Aguayo-Orozco, Joachim Johansen, Jakob Nybo Nissen, Caroline Brorsson, Gianluca Mazzoni, Lili Niu, Jorge Hernansanz Biel, Cristina Leal Rodriguez, Valentas Brasas, Henry Webel, Michael Eriksen Benros, Anders Gorm Pedersen, Piotr Jaroslaw Chmura, Ulrik Plesner Jacobsen, Andrea Mari, Robert Koivula, Anubha Mahajan, Ana Vinuela, Juan Fernandez Tajes, Sapna Sharma, Mark Haid, Mun-Gwan B. Hong, Petra Musholt, Federico De Masi, Josef Vogt, Helle Krogh Pedersen, Valborg Gudmundsdottir, Angus Jones, Gwen Kennedy, Jimmy Bell, E. Louise Thomas, Gary Frost, Henrik Thomsen, Elizaveta Hansen, Tue Haldor Hansen, Henrik Vestergaard, Mirthe T. Muilwijk, Marieke M. Blom, Leen 't Hart, Francois Pattou, Violeta Raverdy, Soren Brage, Tarja Kokkola, Alison Heggie, Donna McEvoy, Miranda Mourby, Jane Kaye, Andrew Hattersley, Timothy McDonald, Martin Ridderstrale, Mark Walker, Ian N. Forgie, Giuseppe Giordano, Imre Pavo, Hartmut Ruetten, Oluf Pedersen, Torben Hansen, Emmanouil W. Dermitzakis, Paul M. Franks, Jochen Schwenk, Jerzy I. Adamski, Mark McCarthy, Ewan Pearson, Karina Banasik, Simon Rasmussen, Soren Brunak
NATURE BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Tomas Gonzales, Justin Jeon, Timothy Lindsay, Kate Westgate, Ignacio Perez-Pozuelo, Stefanie Hollidge, Katrien Wijndaele, Kirsten Rennie, Nita Forouhi, Simon Griffin, Nick Wareham, Soren Brage
Summary: This study evaluates the relationship between resting heart rate (RHR) and cardiorespiratory fitness, finding associations between RHR and fitness, exploring factors that influence this relationship, and demonstrating the utility of RHR for remote population monitoring. The results suggest that RHR is a valid biomarker of cardiorespiratory fitness, and that physical activity and adiposity influence the relationship between RHR and fitness.
Article
Endocrinology & Metabolism
John R. Speakman, Jasper M. A. de Jong, Srishti Sinha, Klaas R. Westerterp, Yosuke Yamada, Hiroyuki Sagayama, Philip N. Ainslie, Liam J. Anderson, Lenore Arab, Kweku Bedu-Addo, Stephane Blanc, Alberto G. Bonomi, Pascal Bovet, Soren Brage, Maciej S. Buchowski, Nancy F. Butte, Stefan G. J. A. Camps, Jamie A. Cooper, Richard Cooper, Sai Krupa Das, Peter S. W. Davies, Lara R. Dugas, Ulf Ekelund, Sonja Entringer, Terrence Forrester, Barry W. Fudge, Melanie Gillingham, Santu Ghosh, Annelies H. Goris, Michael Gurven, Lewis G. Halsey, Catherine Hambly, Hinke H. Haisma, Daniel Hoffman, Sumei Hu, Annemiek M. Joosen, Jennifer L. Kaplan, Peter Katzmarzyk, William E. Kraus, Robert F. Kushner, William R. Leonard, Marie Loef, Corby K. Martin, Eric Matsiko, Anine C. Medin, Erwin P. Meijer, Marian L. Neuhouser, Theresa A. Nicklas, Robert M. Ojiambo, Kirsi H. Pietilaeinen, Jacob Plange-Rhule, Guy Plasqui, Ross L. Prentice, Susan B. Racette, David A. Raichlen, Eric Ravussin, Leanne M. Redman, Susan B. Roberts, Michael C. Rudolph, Luis B. Sardinha, Albertine J. Schuit, Analiza M. Silva, Eric Stice, Samuel S. Urlacher, Giulio Valenti, Ludo M. Van Etten, Edgar A. Van Mil, Brian M. Wood, Jack A. Yanovski, Tsukasa Yoshida, Xueying Zhang, Alexia J. Murphy-Alford, Cornelia U. Loechl, Anura Kurpad, Amy H. Luke, Herman Pontzer, Matthew S. Rodeheffer, Jennifer Rood, Dale A. Schoeller, William W. Wong
Summary: Obesity is caused by prolonged positive energy balance, and the contribution of reduced activity levels to energy expenditure is still debated. Our study shows that total energy expenditure (TEE) adjusted for body composition and age has declined since the late 1980s, while adjusted activity energy expenditure has increased over time in both sexes. The decline in adjusted basal energy expenditure (BEE) is identified as a previously unrecognized factor. These findings suggest that the increasing obesity in the United States/Europe is not likely fueled by reduced physical activity leading to lowered TEE.
Article
Health Care Sciences & Services
Natascha H. Pedersen, Anders Grontved, Jan C. Brond, Niels C. Moller, Kristian T. Larsen, Birgit Debrabant, Sofie Koch, Jens Troelsen, Soren Brage, Jasper Schipperijn, Jacob Hjelmborg, Niels Wedderkopp, Lars B. Christiansen, Peter L. Kristensen
Summary: A new Danish school policy requiring 45 minutes of physical activity daily during school hours was introduced in 2014. This study evaluated the effect of this nationwide policy on physical activity in Danish children and adolescents. The results showed that the policy interrupted the decreasing trend of physical activity during school hours and increased physical activity among students.
LANCET REGIONAL HEALTH-EUROPE
(2023)
Editorial Material
Endocrinology & Metabolism
David E. Kloecker, Soren Brage, Nicholas J. Wareham
Article
Nutrition & Dietetics
Zhu Liduzi Jiesisibieke, Jenna Panter, Mengyao Wang, Shiu Lun Au Yeung, Shan Luo, Haeyoon Jang, Eric Yuk Fai Wan, Soren Brage, Youngwon Kim
Summary: The use of cars as a mode of transportation is associated with an increased risk of coronary heart disease (CHD), but it is unknown whether the association varies based on genetic susceptibility to CHD. This study aimed to investigate the associations between genetic susceptibility, modes of transport, and CHD incidence. The results showed that exclusive car use was associated with a higher risk of CHD across all levels of genetic susceptibility. Using alternatives to the car should be encouraged for the prevention of CHD, especially for individuals at high genetic risk.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2023)
Article
Sport Sciences
Sehrish Naveed, Taisa Sallinen, Aino-Maija Eloranta, Hannamari Skog, Henna Jalkanen, Soren Brage, Ulf Ekelund, Heikki Pentikaeinen, Kai Savonen, Timo A. Lakka, Eero A. Haapala
Summary: In this study, a combined dietary and physical activity intervention in children did not have an effect on cognition. However, improvements in diet quality and participation in organized sports and reading were associated with improved cognition.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Multidisciplinary Sciences
Lina Cai, Tomas Gonzales, Eleanor Wheeler, Nicola D. Kerrison, Felix R. Day, Claudia Langenberg, John R. B. Perry, Soren Brage, Nicholas J. Wareham
Summary: Higher cardiorespiratory fitness is associated with lower risk of type 2 diabetes. Genetic determinants in cardiorespiratory fitness and candidate genes related to cardiac muscle development and muscle contractility were identified. Higher genetically predicted fitness is causally associated with lower risk of type 2 diabetes independent of adiposity.
NATURE COMMUNICATIONS
(2023)