Article
Sport Sciences
Felipe Alves Ribeiro, Carlos Dellavechia de Carvalho, Julia Causin Andreossi, Douglas Rodrigues Messias Miranda, Marcelo Papoti
Summary: This study aimed to investigate the effects of a 6-week specific preparatory period and a 2-week taper period on neuromuscular fatigue profile in 100-m front crawl swimming performance. The results showed that performance improved after both the specific preparatory and taper periods, but neuromuscular fatigue was primarily developed by peripheral mechanisms and was not affected by the training period.
INTERNATIONAL JOURNAL OF SPORTS MEDICINE
(2023)
Article
Sport Sciences
Christopher D. Black, Kody R. Haskins, Michael G. Bemben, Rebecca D. Larson
Summary: This study found that carbohydrate mouth rinsing did not have any effect on central or peripheral fatigue after exercise, indicating that it did not attenuate fatigue during strength-based exercise. Despite larger declines in voluntary activation after low-intensity exercise, carbohydrate mouth rinsing had no effects compared to placebo on any measured variable.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2022)
Article
Physiology
Kenzo C. Kishimoto, Martin E. Heroux, Simon C. Gandevia, Jane E. Butler, Joanna Diong
Summary: This study demonstrated that maximal muscle activity can be estimated from muscle activity produced during submaximal voluntary activation. A simple mathematical relationship between voluntary muscle activation and muscle activity across a broad range of values was found, capable of estimating maximal muscle activity.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Pharmacology & Pharmacy
Fadhli Adesta, Caroline Mahendra, Kathleen Irena Junusmin, Arya Melissa Selva Rajah, Sharon Goh, Levana Sani, Alexandre Chan, Astrid Irwanto
Summary: The survey results indicate a general agreement among healthcare professionals on the benefits of PGx testing. However, there is a lack of self-efficacy and competency in utilizing PGx data. A 90-minute training significantly improves these issues, leading to a greater anticipation of PGx adoption.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Multidisciplinary Sciences
Malte J. Rasch, Charles Mackin, Manuel Le Gallo, An Chen, Andrea Fasoli, Frederic Odermatt, Ning Li, S. R. Nandakumar, Pritish Narayanan, Hsinyu Tsai, Geoffrey W. Burr, Abu Sebastian, Vijay Narayanan
Summary: In this study, a hardware-aware retraining approach is developed to examine the accuracy of analog in-memory computing across multiple network topologies and investigate sensitivity and robustness to a broad set of nonidealities. By introducing a realistic crossbar model, significant improvement is achieved compared to earlier retraining approaches. The results show that many larger-scale deep neural networks can be successfully retrained to show iso-accuracy with the floating point implementation, and nonidealities that add noise to the inputs or outputs have the largest impact on accuracy.
NATURE COMMUNICATIONS
(2023)
Article
Education & Educational Research
Jose Ramon Yuste, Andres Blanco-Di Matteo, Fernando Gruber
Summary: Training in infectious diseases has a significant impact on medical students' perception and knowledge of antibiotic resistance and the rational use of antibiotics. However, knowledge loss becomes a problem as time lapses after training.
BMC MEDICAL EDUCATION
(2022)
Article
Physics, Particles & Fields
Charles Burton, Spencer Stubbs, Peter Onyisi
Summary: In this study, the use of Mixture Density Networks (MDNs) for parameter estimation in situations where training data is only available for discrete values of a continuous parameter is demonstrated. The origins of biases are discussed, and corrective methods for each issue are proposed to address performance-limiting problems that may arise.
EUROPEAN PHYSICAL JOURNAL C
(2021)
Article
Geochemistry & Geophysics
Tao He, Bangyu Wu, Xu Zhu
Summary: In this letter, a multi-stage training process is proposed to train multiple U-net models, each focusing on interpolating different missing components with a small amplitude range, improving the accuracy of interpolation results.
IEEE GEOSCIENCE AND REMOTE SENSING LETTERS
(2022)
Article
Agriculture, Dairy & Animal Science
Adriana Garzon, Rafael Portillo, Gregory Habing, Noelia Silva-del-Rio, Betsy M. Karle, Richard V. Pereira
Summary: This study developed and evaluated an on-farm educational program for dairy farmworkers to improve their knowledge and skills in antimicrobial stewardship for adult cattle. The results showed significant improvement in knowledge and attitudes after completing the training.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Infectious Diseases
Naomi Weier, Dilip Nathwani, Karin Thursky, Thomas Tangden, Vera Vlahovic-Palcevski, Oliver Dyar, Bojana Beovi, Gabriel Levy Hara, Rahul Patel, Celine Pulcini, Syed Tabish R. Zaidi
Summary: This study identified 48 unique AMS training programmes globally through online survey and search, with less than half of respondents aware of available AMS programmes. Pharmacists showed higher awareness compared to medical doctors and other professionals. Most AMS training programmes were delivered online and targeted medical doctors. The main barriers to participation were training costs and lack of recognition by health professional societies.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Engineering, Electrical & Electronic
Minghui Huang, Shijun Xiang
Summary: This paper introduces a new direct cross downsampling (DCD) algorithm and its DCD-based interpolation methods. By comparing with the traditional direct downsampling (DD) algorithm, experimental results demonstrate the superiority of the DCD algorithm.
DIGITAL SIGNAL PROCESSING
(2022)
Article
Biophysics
Andrei L. Perez Olivera, Matthew C. Solan, Kiros Karamanidis, Katya N. Mileva, Darren C. James
Summary: The study found that voluntary exercises are limited in their ability to fully activate the strongest intrinsic foot muscle, but targeted neuromuscular electrical stimulation may be effective in overcoming this limitation.
JOURNAL OF BIOMECHANICS
(2022)
Article
Optics
Xiangbo Liu, Xiaobo Li, Shih-Chi Chen
Summary: In this Letter, a new method for calculating angle of polarization (AoP) loss is presented and applied in an enhanced color polarization demosaicking network. Experimental results demonstrate the effectiveness and superiority of the method, which has potential applications in the field of polarimetric imaging.
Article
Physiology
Tiril Toien, Havard Haglo, Stian Kwak Nyberg, Shalini Vasudev Rao, Astrid Kamilla Stunes, Mats Peder Mosti, Eivind Wang
Summary: Maximal strength training (MST) leads to significant improvements in strength and rate of force development, as well as increased efferent neural drive to maximally contracting skeletal muscle, without affecting SERCA expression.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Computer Science, Software Engineering
Bingcai Wu, Junyan Ma, Lutao Wei, Xiaoping Liao, Juan Lu
Summary: This paper proposes an improved feedrate scheduling scheme that processes S-shaped quartic and cubic feedrate profiles to ensure machining quality and efficiency, while satisfying the chord error constraints as much as possible.
COMPUTER-AIDED DESIGN
(2022)
Article
Physiology
Jayne C. Carberry, Peter G. R. Burke, Amal M. Osman, Lauriane Juge, Barbara Toson, Simon C. Gandevia, Jane E. Butler, Lynne E. Bilston, Danny J. Eckert
Summary: The movement patterns of tongue and upper airway dilator muscles during quiet breathing vary in people with obstructive sleep apnea (OSA). Our study found regional heterogeneity in genioglossus reflex responses in OSA patients, as well as variability in reflex morphology. The findings also suggest a possible association between the size of the pharyngeal airway and the amplitude of genioglossus reflex response to negative pressure.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Letter
Physiology
Martin E. Heroux, Annie A. Butler, Lucy S. Robertson, Georgia Fisher, Jean-Sebastien Blouin, Joanna Diong, Carmen Krewer, Francois Tremblay, Simon C. Gandevia
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Physiology
Billy L. Luu, R. H. Chaminda Lewis, Simon C. Gandevia, Claire L. Boswell-Ruys, Jane E. Butler
Summary: This study explored sensations of breathing following tetraplegia and found that the detection threshold for an added resistive load during inspiration was higher in tetraplegia group compared to able-bodied controls. However, for inspiratory loads above the detection threshold, the perceived magnitude of a resistive load as a function of the peak inspiratory pressure was greater in tetraplegia. Load magnitude perception was similar between participant groups when peak pressure was divided by maximal inspiratory pressure.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Review
Neurosciences
Lewis A. Ingram, Annie A. Butler, Stephen R. Lord, Simon C. Gandevia
Summary: Profiling performance in the physiological domains underpinning upper limb function provides insight into an individual's specific impairments. A battery of tests were used to create a core upper limb physiological profile assessment (PPA). Individual performance in each test can be compared to a reference population score, and a composite score provides an overview of overall upper limb function.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Neurosciences
Eduardo Martinez-Valdes, Roger M. Enoka, Ales Holobar, Kevin McGill, Dario Farina, Manuela Besomi, Francois Hug, Deborah Falla, Richard G. Carson, Edward A. Clancy, Catherine Disselhorst-Klug, Jaap H. van Dieen, Kylie Tucker, Simon Gandevia, Madeleine Lowery, Karen Sogaard, Thor Besier, Roberto Merletti, Matthew C. Kiernan, John C. Rothwell, Eric Perreault, Paul W. Hodges
Summary: The analysis of single motor unit (SMU) activity is crucial for understanding the neural strategies controlling muscle force. Traditionally, this analysis has been done invasively through intramuscular electromyography (EMG), but recent advances in signal processing techniques have enabled the identification of SMU activity in high-density surface electromyography (HDsEMG) recordings.
JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY
(2023)
Article
Neurosciences
Gabrielle Todd, Caroline D. Rae, Janet L. Taylor, Nigel C. Rogasch, Jane E. Butler, Michael Hayes, Robert A. Wilcox, Simon C. Gandevia, Karl Aoun, Adrian Esterman, Simon J. G. Lewis, Julie M. Hall, Elie Matar, Jana Godau, Daniela Berg, Christian Plewnia, Anna-Katharina Von Thaler, Clarence Chiang, Kay L. Double
Summary: Research has found that increased thickness of the substantia nigra in healthy older adults may be associated with changes in excitability of motor cortical circuitry. This finding has important implications for understanding brain changes in healthy older adults at risk of Parkinson's disease.
JOURNAL OF NEUROSCIENCE RESEARCH
(2023)
Letter
Neurosciences
Markus Amann, Simranjit Sidhu, Chris McNeil, Simon Gandevia
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Article
Multidisciplinary Sciences
Eric Yung-Sheng Su, Timothy J. Carroll, Dominic J. Farris, Glen A. Lichtwark
Summary: Through computer modeling and simulation, we explored the potential influence of accentuated eccentric loading (AEL) on enhanced power and energy storage during vertical jumping. However, our model did not show improved jump performance with AEL, and there was no additional tendon-loading effect compared to non-AEL condition.
Article
Clinical Neurology
Annie A. Butler, Joanna Diong, Kajsa Lidman, Johanna Adler, Daniel L. Wardman, Simon C. Gandevia, Martin E. Heroux
Summary: This study aimed to quantify the severity of proprioceptive deficits in people with essential tremor (ET) and estimate how these contribute to functional impairments. Results showed that upper limb function but not proprioception was impaired in ET, indicating that the central nervous system of people with ET is able to accommodate mild to moderate tremor in active proprioceptive tasks.
TREMOR AND OTHER HYPERKINETIC MOVEMENTS
(2023)
Article
Physiology
Patricio A. Pincheira, Dean L. Mayfield, Aaron S. Fox, Nicholas A. T. Brown, Timothy J. Carroll, Andrew G. Cresswell, Glen A. Lichtwark
Summary: This study investigated the effect of muscle force during active stretch on exercise-induced muscle damage. The results showed that adding 30% body weight during eccentric contractions did have some impact on muscle damage, but did not increase torque loss or intensify muscle soreness.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Geriatrics & Gerontology
Steven Phu, Michela Persiani, Brandon Tan, Matthew Brodie, Simon Gandevia, Daina L. Sturnieks, Stephen R. Lord
Summary: This study examined the effects of optic flow stimuli presented in different directions on postural stability in young and older adults. The results showed that optic flow stimuli increased postural sway and muscle activity, with a greater impact on older adults, particularly in the mediolateral plane for those at high risk of falls.
EXPERIMENTAL GERONTOLOGY
(2023)
Article
Biology
Cristian D. Riveros-Matthey, Timothy J. Carroll, Glen A. Lichtwark, Mark J. Connick
Summary: People tend to choose higher cadences than metabolic optimal during bicycling, which may allow for optimal muscle power. However, it is unclear whether this is consistent across different power outputs.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2023)
Editorial Material
Neurosciences
Markus Amann, Simranjit K. Sidhu, Chris J. McNeil, Simon C. Gandevia
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Correction
Physiology
B. L. Luu, R. H. C. Lewis, S. C. Gandevia, C. L. Boswell-Ruys, J. E. Butler
Summary: This study examined the sensations of breathing after tetraplegia. The findings showed that individuals with chronic tetraplegia had a higher detection threshold for added resistance during inspiration compared to able-bodied controls. However, both groups perceived larger loads as more effortful, with perception related to maximal inspiratory muscle force rather than absolute force.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Neurosciences
Lauriane Juge, Angela Liao, Jade Yeung, Fiona L. Knapman, Christopher Bull, Peter G. R. Burke, Elizabeth C. Brown, Simon C. Gandevia, Danny J. Eckert, Jane E. Butler, Lynne E. Bilston
Summary: This study investigated the relationship between inspiratory tongue dilatory movement and genioglossus muscle activity in individuals with and without obstructive sleep apnoea (OSA). The results showed that tongue movement cannot be predicted by genioglossus electromyography (EMG), especially in OSA patients, suggesting the involvement of other airway dilator muscles in tongue movement.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)