Article
Geriatrics & Gerontology
Cillian P. McDowell, Louise Newman, Derek C. Monroe, John D. O'Connor, Silvin P. Knight, Rose Anne Kenny, Matt P. Herring
Summary: Individuals with generalized anxiety disorder (GAD) exhibit lower prefrontal cortical oxygenation, but this association is modified by physical activity (PA), suggesting that PA may help protect brain health in older adults with GAD.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Hospitality, Leisure, Sport & Tourism
Nicolas Kakouris, Numan Yener, Daniel T. P. Fong
Summary: This study systematically reviewed the literature to determine the incidence and prevalence of running-related musculoskeletal injuries. It found that there was no significant difference in injury incidence between ultramarathon runners and non-ultramarathon runners, and identified specific pathologies with high incidence proportions. The interpretation of epidemiological data in this area is limited by methodological issues.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2021)
Editorial Material
Oncology
Marwa Zerhouni, Elena Piskounova
Summary: This study investigates the impact of exercise on melanoma growth and metastasis, revealing that exercise can decrease metastatic spread and inhibit melanoma progression through systemic metabolic reprogramming. The study also discovers a direct link between metabolic reprogramming and mTOR signaling, providing novel opportunities for therapeutic intervention.
Review
Endocrinology & Metabolism
Sabrina E. Noel, Michelly P. Santos, Nicole C. Wright
Summary: Osteoporosis is a bone disease with racial and ethnic disparities in bone outcomes. Variations in bone density, prevalence of osteoporosis and fractures, as well as disparities in screening and treatment exist across different racial and ethnic groups. Suboptimal osteoporosis management and postfracture care may be experienced by non-Hispanic black, Hispanic, and Asian populations, highlighting the need for additional population-based studies.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Nan Zhang, Ziheng Jia, Tianshu Gu, Yi Zheng, Yunpeng Zhang, Wenhua Song, Ziliang Chen, Guangping Li, Gary Tse, Tong Liu
Summary: This study explores the causal relationships between genetically predicted risk factors and frailty, finding significant associations between genetic liability to certain diseases and lifestyle factors with increased risk of frailty. It also identifies a negative association between college education and high-density lipoprotein cholesterol level with frailty risk.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2023)
Article
Endocrinology & Metabolism
Marko T. Korhonen, Urho M. Kujala, Jyrki Kettunen, Olga V. Korhonen, Jaakko Kaprio, Seppo Sarna, Timo Tormakangas
Summary: Maintenance of vigorous exercise habits from young to old age is considered protective against hip fractures. This study found that continuing high-intensity exercise in old age is associated with a lower hazard rate of hip fractures, although this protective effect diminishes with age.
JOURNAL OF BONE AND MINERAL RESEARCH
(2022)
Article
Geriatrics & Gerontology
Andrea Mayo, Martin Senechal, Jonathan Boudreau, Mathieu Belanger, Danielle R. Bouchard
Summary: This study found that the sum of all physical activities is related to physical function for aging adults, regardless of current physical activity guidelines. Therefore, the current guidelines may not fully consider factors that could improve physical function in older adults.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Review
Geriatrics & Gerontology
Maria B. Renke, Anna B. Marcinkowska, Sylwester Kujach, Pawel J. Winklewski
Summary: A literature review found no direct evidence to support a link between exercise-induced increase in brain perfusion and better cognitive functioning, but further research is needed to confirm this.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Sport Sciences
Anny Fredette, Jean-Sebastien Roy, Kadija Perreault, Frederique Dupuis, Christopher Napier, Jean-Francois Esculier
Summary: This study aims to synthesize the current evidence on the incidence of running-related injuries (RRIs) and their association with training parameters. The study included 36 articles involving 23,047 runners. Overall, RRIs have a high incidence, but the current evidence does not consistently link RRIs with specific training parameters.
JOURNAL OF ATHLETIC TRAINING
(2022)
Article
Neurosciences
Keyin Shen, Xingran Liu, Dandan Chen, Jingru Chang, Ying Zhang, Xianjuan Kou
Summary: Autophagy is a crucial cellular process implicated in Alzheimer's disease and aging. miR-130a plays a key role in regulating brain autophagy and cell senescence, with exercise being able to reverse impaired autophagy resulted from aging. Overexpression of miR-130a can attenuate cell senescence and impaired autophagy, suggesting a potential therapeutic approach for brain aging.
BRAIN RESEARCH BULLETIN
(2021)
Article
Cardiac & Cardiovascular Systems
Matt T. Oberdier, Majd AlGhatrif, Fatemeh Adelnia, Marta Zampino, Christopher H. Morrell, Eleanor Simonsick, Kenneth Fishbein, Edward G. Lakatta, Mary M. McDermott, Luigi Ferrucci
Summary: In individuals without peripheral arterial disease, a greater decline in ABI over time is associated with a faster decline in thigh muscle mitochondrial oxidative capacity in the ipsilateral leg.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Endocrinology & Metabolism
Carrie-Anne Ng, David Scott, Markus J. Seibel, Robert G. Cumming, Vasi Naganathan, Fiona M. Blyth, David G. Le Couteur, Louise M. Waite, David J. Handelsman, Vasant Hirani
Summary: High-impact physical activities with bone strains of high magnitude and frequency can benefit bone health in older men. Engaging in activities with high and rapid impact helps maintain higher bone mineral density and reduce the risk of falls, while high energy expenditure is associated with a reduced falls risk. Integrating traditional physical activity data with bone loading estimates may enhance the understanding of the relationships between physical activity and bone health.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Borja del Pozo Cruz, Matthew Ahmadi, Elif Inan-Eroglu, Bo-Huei Huang, Emmanuel Stamatakis
Summary: This study explores the dose-response associations of device-assessed physical activity with mortality and incidence of cardiovascular disease (CVD) in adults with hypertension. The findings highlight the importance of physical activity for individuals with hypertension and provide novel insights for developing physical activity guidelines for this high-risk group.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Geriatrics & Gerontology
Annesofie Thorup Olesen, Lasse Alchow-Moller, Rune Duus Bendixen, Michael Kjaer, Rene Bruggebusch Svensson, Jesper Lovind Andersen, S. Peter Magnusson
Summary: The study showed that ten weeks of high intensity training could attenuate age-related loss of muscle mass and function, with greater effects observed in old mice in the HR group. The HR running increased fiber CSA and shifted fiber types in the older mice, suggesting its effectiveness in counteracting sarcopenia.
EXPERIMENTAL GERONTOLOGY
(2021)
Article
Geriatrics & Gerontology
Deepti Chugh, Chitra C. Iyer, Prameela Bobbili, Anton J. Blatnik, Brian K. Kaspar, Kathrin Meyer, Arthur H. M. Burghes, Brian C. Clark, W. David Arnold
Summary: The combination of exercise and FST overexpression has positive effects on neuromuscular junction transmission and muscle mass in aging mice, but does not affect motor unit degeneration.
NEUROBIOLOGY OF AGING
(2021)