Revisiting Human IL-12Rβ1 Deficiency

A 475 years-old founder effect involving IL12RB1: A highly prevalent mutation conferring Mendelian Susceptibility to Mycobacterial Diseases in European descendants

(2009) J. Yancoski et al.   INFECTION GENETICS AND EVOLUTION

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

(2009) Matteo Fumagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

(2009) Heather R. Conti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-12/-23 receptor beta 1 deficiency in an infant with draining BCG lymphadenitis

(2009) Suna Asilsoy et al.   PEDIATRICS INTERNATIONAL

A role for interleukin-12/23 in the maturation of human natural killer and CD56+ T cells in vivo

(2008) S. Guia et al.   BLOOD

Influenza Virus Vaccination Induces Interleukin-12/23 Receptor  1 (IL-12/23R 1)-Independent Production of Gamma Interferon (IFN- ) and Humoral Immunity in Patients with Genetic Deficiencies in IL-12/23R 1 or IFN-  Receptor I

(2008) T. de Boer et al.   Clinical and Vaccine Immunology

Simultaneous presentation of 2 rare hereditary immunodeficiencies: IL-12 receptor β1 deficiency and ataxia-telangiectasia

(2008) Mohammad Ehlayel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases

(2008) Saleh Al-Muhsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chinese Patients with Defective IL-12/23-Interferon-γ Circuit in Taiwan: Partial Dominant Interferon-γ Receptor 1 Mutation Presenting as Cutaneous Granuloma and IL-12 Receptor β1 Mutation as Pneumatocele

(2008) Wen-I Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disseminated Mycobacterium avium Infection in a Patient with a Novel Mutation in the Interleukin-12 Receptor-β1 Chain

(2008) Filomeen Haerynck et al.   JOURNAL OF PEDIATRICS

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

(2008) Craig L Leonardi et al.   LANCET

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

(2008) Kim A Papp et al.   LANCET

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

(2008) J. Z. Li et al.   SCIENCE