标题
Sigma-2 Receptor Ligands and Their Perspectives in Cancer Diagnosis and Therapy
作者
关键词
-
出版物
MEDICINAL RESEARCH REVIEWS
Volume 34, Issue 3, Pages 532-566
出版商
Wiley
发表日期
2013-08-07
DOI
10.1002/med.21297
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Assessment of Cellular Proliferation in Tumors by PET Using 18F-ISO-1
- (2013) F. Dehdashti et al. JOURNAL OF NUCLEAR MEDICINE
- Inhibitory Effects of Sigma-2 Receptor Agonists on T Lymphocyte Activation
- (2013) Miguel A. Iñiguez et al. Frontiers in Pharmacology
- 7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands
- (2012) Samuel D. Banister et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of a novel 99mTc cyclopentadienyl tricarbonyl complex ([(Cp-R)99mTc(CO)3]) for sigma-2 receptor tumor imaging
- (2012) Xin Chen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Sigma-2 ligands induce tumour cell death by multiple signalling pathways
- (2012) C Zeng et al. BRITISH JOURNAL OF CANCER
- 2-Aminopyridine Derivatives as Potential σ2Receptor Antagonists
- (2012) Carmen Abate et al. ChemMedChem
- Classes of Sigma2 (σ2) Receptor Ligands: Structure Affinity Relationship (SAfiR) Studies and Antiproliferative Activity
- (2012) Carmen Abate et al. CURRENT PHARMACEUTICAL DESIGN
- Progesterone Regulation of Progesterone Receptor Membrane Component 1 (PGRMC1) Sumoylation and Transcriptional Activity in Spontaneously Immortalized Granulosa Cells
- (2012) John J. Peluso et al. ENDOCRINOLOGY
- S2RPgrmc1: the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling
- (2012) Ikhlas S A Ahmed et al. Expert Opinion on Drug Metabolism & Toxicology
- Neutrophil Gelatinase-associated Lipocalin (NGAL) Expression Is Dependent on the Tumor-associated Sigma-2 Receptor S2RPgrmc1
- (2012) Shakeel U. R. Mir et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysosomal Membrane Permeabilization is an Early Event in Sigma-2 Receptor Ligand Mediated Cell Death in Pancreatic Cancer
- (2012) John R Hornick et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Evidence for a genomic mechanism of action for progesterone receptor membrane component-1
- (2012) John J. Peluso et al. STEROIDS
- Electron-donating para-methoxy converts a benzamide-isoquinoline derivative into a highly Sigma-2 receptor selective ligand
- (2011) Abdol R. Hajipour et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Effect of structural modification in the amine portion of substituted aminobutyl-benzamides as ligands for binding σ1 and σ2 receptors
- (2011) Kuo-Hsien Fan et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Use of Multifunctional Sigma-2 Receptor Ligand Conjugates to Trigger Cancer-Selective Cell Death Signaling
- (2011) D. Spitzer et al. CANCER RESEARCH
- Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands
- (2011) Mine Yarim et al. Chemical Biology & Drug Design
- Synthesis and pharmacological evaluation of indole-based sigma receptor ligands
- (2011) Christophe Mésangeau et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers
- (2011) Carmen Abate et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients
- (2011) Shakeel U.R. Mir et al. INTERNATIONAL JOURNAL OF CANCER
- Synthesis and Biological Characterization of 3-Substituted-1H-indoles as Ligands of GluN2B-ContainingN-Methyl-d-aspartate Receptors
- (2011) Rosaria Gitto et al. JOURNAL OF MEDICINAL CHEMISTRY
- Fluorescent Derivatives of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a Tool for Uptake and Cellular Localization Studies in Pancreatic Tumor Cells
- (2011) Carmen Abate et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sigma-2 Receptor as Potential Indicator of Stem Cell Differentiation
- (2011) Jodi L. Haller et al. MOLECULAR IMAGING AND BIOLOGY
- SV119-gold nanocage conjugates: a new platform for targeting cancer cellsvia sigma-2 receptors
- (2011) Yucai Wang et al. Nanoscale
- Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
- (2011) Jinbin Xu et al. Nature Communications
- Radiosynthesis and biological evaluation of a promising σ2-receptor ligand radiolabeled with fluorine-18 or iodine-125 as a PET/SPECT probe for imaging breast cancer
- (2010) Zhude Tu et al. APPLIED RADIATION AND ISOTOPES
- A 3D-pharmacophore model for σ2 receptors based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives
- (2010) Erik Laurini et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Sigma Receptors in Oncology: Therapeutic and Diagnostic Applications of Sigma Ligands
- (2010) Aren van Waarde et al. CURRENT PHARMACEUTICAL DESIGN
- Early development of sigma-receptor ligands
- (2010) Sanju Narayanan et al. Future Medicinal Chemistry
- Pgrmc1 (Progesterone Receptor Membrane Component 1) Associates with Epidermal Growth Factor Receptor and Regulates Erlotinib Sensitivity
- (2010) Ikhlas S. Ahmed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Progesterone Receptor Membrane Component 1 (Pgrmc1): A Heme-1 Domain Protein That Promotes Tumorigenesis and Is Inhibited by a Small Molecule
- (2010) I. S. Ahmed et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Sigma receptors and their ligands in cancer biology: overview and new perspectives for cancer therapy
- (2010) Véronique Megalizzi et al. MEDICINAL RESEARCH REVIEWS
- The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine
- (2010) John R Hornick et al. Molecular Cancer
- F281, synthetic agonist of the sigma-2 receptor, induces Ca2+ efflux from the endoplasmic reticulum and mitochondria in SK-N-SH cells
- (2009) Giuseppe Cassano et al. CELL CALCIUM
- Exploring the Importance of Piperazine N-Atoms for σ2Receptor Affinity and Activity in a Series of Analogs of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28)†
- (2009) Francesco Berardi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma
- (2009) Hiroyuki Kashiwagi et al. Journal of Translational Medicine
- New N-substituted 9-azabicyclo[3.3.1]nonan-3α-yl phenylcarbamate analogs as σ2 receptor ligands: Synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents
- (2008) Wenhua Chu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Conversion of a Highly Selective Sigma-1 Receptor–Ligand to Sigma-2 Receptor Preferring Ligands with Anticocaine Activity
- (2008) Christophe Mésangeau et al. JOURNAL OF MEDICINAL CHEMISTRY
- PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling, P450 activation and drug binding
- (2008) Hannah J. Rohe et al. PHARMACOLOGY & THERAPEUTICS
- Tritium radiolabelling of PB28, a potent sigma-2 receptor ligand: pharmacokinetic and pharmacodynamic characterization
- (2007) Nicola Antonio Colabufo et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now