Protein kinases CK1 and CK2 as new targets for neurodegenerative diseases

Identification of casein kinase-1 phosphorylation sites on TDP-43

(2009) Fuyuki Kametani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2

(2009) Giorgio Cozza et al.   BIOCHEMICAL JOURNAL

Synthesis and kinase inhibitory activity of novel substituted indigoids

(2009) Anne Beauchard et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2

(2009) Alessandra Gianoncelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Protein Kinase CK2 in Health and Disease

(2009) K. Niefind et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) J. H. Trembley et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

New Protein Kinase CK2 Inhibitors: Jumping out of the Catalytic Box

(2009) Renaud Prudent et al.   CHEMISTRY & BIOLOGY

Neurochemical Approaches in the Laboratory Diagnosis of Parkinson and Parkinson Dementia Syndromes: A Review

(2009) Sarah Jesse et al.   CNS Neuroscience & Therapeutics

Trends in the Molecular Pathogenesis and Clinical Therapeutics of Common Neurodegenerative Disorders

(2009) Yahya Choonara et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophosphorylation of carboxy-terminal residues inhibits the activity of protein kinase CK1α

(2009) Mauricio Budini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

3,4-Diaryl-isoxazoles and -imidazoles as Potent Dual Inhibitors of p38α Mitogen Activated Protein Kinase and Casein Kinase 1δ†

(2009) Christian Peifer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress

(2009) Florence Chaverneff et al.   JOURNAL OF NEUROCHEMISTRY

Selective Inhibition of Casein Kinase 1  Minimally Alters Circadian Clock Period

(2009) K. M. Walton et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Targeting protein kinases in central nervous system disorders

(2009) Laura K. Chico et al.   NATURE REVIEWS DRUG DISCOVERY

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

(2009) G. Pigino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic transmission block by presynaptic injection of oligomeric amyloid beta

(2009) H. Moreno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of casein kinase I ε/δ produces phase shifts in the circadian rhythms of Cynomolgus monkeys

(2009) Jeffrey Sprouse et al.   PSYCHOPHARMACOLOGY

Protein kinase inhibitors: contributions from structure to clinical compounds

(2009) Louise N. Johnson   QUARTERLY REVIEWS OF BIOPHYSICS

Different expression patterns of CK2 subunits in the brains of experimental animals and patients with transmissible spongiform encephalopathies

(2008) Jian-Ming Chen et al.   ARCHIVES OF VIROLOGY

Casein Kinase I epsilon positively regulates the Akt pathway in breast cancer cell lines

(2008) Cristina Modak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The selectivity of inhibitors of protein kinase CK2: an update

(2008) Mario A. Pagano et al.   BIOCHEMICAL JOURNAL

Tumorigenesis and neurodegeneration: two sides of the same coin?

(2008) John F. Staropoli   BIOESSAYS

Identification of novel protein kinase CK1 delta (CK1δ) inhibitors through structure-based virtual screening

(2008) Giorgio Cozza et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The CK2α/CK2β Interface of Human Protein Kinase CK2 Harbors a Binding Pocket for Small Molecules

(2008) Jennifer Raaf et al.   CHEMISTRY & BIOLOGY

Identification of Polyoxometalates as Nanomolar Noncompetitive Inhibitors of Protein Kinase CK2

(2008) Renaud Prudent et al.   CHEMISTRY & BIOLOGY

ATP-Noncompetitive Inhibitors of CDK-Cyclin Complexes

(2008) Mar Orzáez et al.   ChemMedChem

Protein Kinase CK2 in Human Diseases

(2008) Barbara Guerra et al.   CURRENT MEDICINAL CHEMISTRY

Hemoglobin Neurotoxicity is Attenuated by Inhibitors of the Protein Kinase CK2 Independent of Heme Oxygenase Activity

(2008) Jing Chen-Roetling et al.   CURRENT NEUROVASCULAR RESEARCH

Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo

(2008) C Brockschmidt et al.   GUT

Roscovitine-Derived, Dual-Specificity Inhibitors of Cyclin-Dependent Kinases and Casein Kinases 1

(2008) Nassima Oumata et al.   JOURNAL OF MEDICINAL CHEMISTRY

Specificity and Regulation of Casein Kinase-Mediated Phosphorylation of α-Synuclein

(2008) Elisa A. Waxman et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Protein kinase CK2 modulates synaptic plasticity by modification of synaptic NMDA receptors in the hippocampus

(2008) Rie Kimura et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mass Spectrometry Analysis of a Protein Kinase CK2β Subunit Interactome Isolated from Mouse Brain by Affinity Chromatography

(2008) Giorgio Arrigoni et al.   JOURNAL OF PROTEOME RESEARCH

Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

(2008) Dianne Baunbæk et al.   Marine Drugs

Expanding the chemical diversity of CK2 inhibitors

(2008) Renaud Prudent et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo

(2008) Silvio E. Perea et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Identification of chemical inhibitors of protein-kinase CK2 subunit interaction

(2008) Béatrice Laudet et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A structural insight into CK2 inhibition

(2008) Marco Mazzorana et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Protein kinase CK2 links extracellular growth factor signaling with the control of p27Kip1 stability in the heart

(2008) Ludger Hauck et al.   NATURE MEDICINE

Setting Clock Speed in Mammals: The CK1ɛ tau Mutation in Mice Accelerates Circadian Pacemakers by Selectively Destabilizing PERIOD Proteins

(2008) Qing-Jun Meng et al.   NEURON

A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine

(2008) Camron D. Bryant et al.   PSYCHOPHARMACOLOGY

Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest

(2008) Wan Seok Yang et al.   GENOME BIOLOGY

Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2

(2007) James S. Duncan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Localization of CKII β subunits in Lewy bodies of Parkinson's disease

(2007) Myung Yi Ryu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole

(2002) Roberto Battistutta et al.   PROTEIN SCIENCE