Codon-biased translation can be regulated by wobble-base tRNA modification systems during cellular stress responses

Role of Metabolic H2O2Generation

(2014) Helmut Sies   JOURNAL OF BIOLOGICAL CHEMISTRY

Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry

(2014) Dan Su et al.   Nature Protocols

Adaptive Translation as a Mechanism of Stress Response and Adaptation

(2013) Tao Pan   Annual Review of Genetics

A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

(2013) Ulrike Begley et al.   EMBO Molecular Medicine

A Role for tRNA Modifications in Genome Structure and Codon Usage

(2012) Eva Maria Novoa et al.   CELL

Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response

(2012) Ashish Patil et al.   CELL CYCLE

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression

(2012) Andrew J Oler et al.   EMBO JOURNAL

Misacylation of tRNA with methionine in Saccharomyces cerevisiae

(2012) E. Wiltrout et al.   NUCLEIC ACIDS RESEARCH

Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications

(2012) Ashish Patil et al.   RNA Biology

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

(2012) Clement T.Y. Chan et al.   Nature Communications

The gene-specific codon counting database: a genome-based catalog of one-, two-, three-, four- and five-codon combinations present in Saccharomyces cerevisiae genes

(2012) Sudheer Tumu et al.   Database-The Journal of Biological Databases and Curation

Transfer RNA Methytransferases and Their Corresponding Modifications in Budding Yeast and Humans: Activities, Predications, and Potential Roles in Human Health

(2011) William L. Towns et al.   DNA AND CELL BIOLOGY

Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice

(2011) T. Hoshino et al.   JOURNAL OF NEUROSCIENCE

Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

(2011) Pavel Ivanov et al.   MOLECULAR CELL

Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation

(2011) D. Graczyk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp60 and heme oxygenase-1 (Hsp32) in acute myocardial infarction

(2011) Giuseppina Novo et al.   Translational Research

Molecular Basis of RNA Polymerase III Transcription Repression by Maf1

(2010) Alessandro Vannini et al.   CELL

An Evolutionarily Conserved Mechanism for Controlling the Efficiency of Protein Translation

(2010) Tamir Tuller et al.   CELL

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding

(2010) L. Songe-Moller et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA repair defects sensitize cells to anticodon nuclease yeast killer toxins

(2010) Roland Klassen et al.   MOLECULAR GENETICS AND GENOMICS

Synonymous but not the same: the causes and consequences of codon bias

(2010) Joshua B. Plotkin et al.   NATURE REVIEWS GENETICS

The RNA modification database, RNAMDB: 2011 update

(2010) W. A. Cantara et al.   NUCLEIC ACIDS RESEARCH

A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress

(2010) Clement T. Y. Chan et al.   PLoS Genetics

3′ processing of eukaryotic precursor tRNAs

(2010) Richard J. Maraia et al.   Wiley Interdisciplinary Reviews-RNA

Aminoacyl-tRNA Synthesis and Translational Quality Control

(2009) Jiqiang Ling et al.   Annual Review of Microbiology

A Novel Human AlkB Homologue, ALKBH8, Contributes to Human Bladder Cancer Progression

(2009) K. Shimada et al.   CANCER RESEARCH

Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1

(2009) Yuehua Wei et al.   EMBO JOURNAL

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

(2009) A. Huber et al.   GENES & DEVELOPMENT

Regulation of RNA Polymerase III Transcription InvolvesSCH9-dependent andSCH9-independent Branches of the Target of Rapamycin (TOR) Pathway

(2009) JaeHoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress inSaccharomyces cerevisiae

(2009) Debrah M. Thompson et al.   JOURNAL OF CELL BIOLOGY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Innate immune and chemically triggered oxidative stress modifies translational fidelity

(2009) Nir Netzer et al.   NATURE

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Stress induces tRNA cleavage by angiogenin in mammalian cells

(2008) Hanjiang Fu et al.   FEBS LETTERS

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1

(2008) I. Chernyakov et al.   GENES & DEVELOPMENT

It's a mod mod tRNA world

(2008) Richard J Maraia et al.   Nature Chemical Biology

tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia

(2008) Birgit S Budde et al.   NATURE GENETICS

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Aminoacyl tRNA synthetases and their connections to disease

(2008) S. G. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA