Technical Note: Homogeneity of Gafchromic® EBT2 film

Methods: A scan protocol established for EBT film and published previously was used. The uniformity of the film coloration was investigated for unirradiated and irradiated EBT2 film sheets. The dose response of EBT2 film was measured and the influence of film inhomogeneities on dose determination was evaluated. Results: Inhomogeneities in pixel values of up to +/- 3.7% within one film were detected. The relative inhomogeneities were found to be approximately independent of the dose. Nonuniformities of the film response lead to uncertainties in dose determination of +/- 8.7% at 1 Gy. When using net optical densities for dose calibration, uncertainties in dose determination amount to more than +/- 6%. Conclusions: EBT2 films from the lot investigated in this study show response inhomogeneities, which lead to uncertainties in dose determination exceeding the commonly accepted tolerance levels. It is important to test further EBT2 lots regarding homogeneity before using the film in clinical routine.